- Oral microbiology and periodontitis research
- Dental materials and restorations
- Periodontal Regeneration and Treatments
- Dental Implant Techniques and Outcomes
- Endodontics and Root Canal Treatments
- Oral Health Pathology and Treatment
- Dental Research and COVID-19
- Dental Radiography and Imaging
- Mesenchymal stem cell research
- Additive Manufacturing and 3D Printing Technologies
- 3D Printing in Biomedical Research
- Proteoglycans and glycosaminoglycans research
- Bone Tissue Engineering Materials
- Immune Response and Inflammation
- Photopolymerization techniques and applications
- Inflammatory mediators and NSAID effects
- Streptococcal Infections and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Eosinophilic Esophagitis
- Bone and Dental Protein Studies
- Salivary Gland Disorders and Functions
- S100 Proteins and Annexins
- Microscopic Colitis
- Dental Erosion and Treatment
- Infective Endocarditis Diagnosis and Management
Ludwig-Maximilians-Universität München
2016-2025
LMU Klinikum
2019-2025
Poliklinik für Zahnerhaltung und Parodontologie
2023
Abstract Objective This study investigated the effect of eluates conventional and 3D‐printed resin materials for manufacturing temporary dental restorations on gingival keratinocytes. Methods Three‐dimensional (3D)‐printed materials: 3Delta temp (Deltamed), NextDent MFH (Nextdent), Freeprint (Detax), GC (GC), were compared to Grandio disc (Voco) Luxatemp (DMG). Human keratinocytes (IHGKs) exposed XTT assays performed at 24 h, 48 72 or 144 h. For quantification proinflammatory response,...
This study aims to analyse the association between baseline microbial load of selected periodontopathogenic bacteria collected from gingival crevicular fluid (GCF) and primary outcome steps I II therapy.
Abstract Background Amelogenin is an extracellular matrix protein well known for its role in the organization and mineralization of enamel. Clinically, it used periodontal regeneration and, due to finding also predentin intercellular spaces dental pulp cells, has recently been suggested capping procedures. The aim this study was analyse vitro effect recombinant human full-length amelogenin on growth differentiation stem cells (hDPSCs). Methods Human DPSCs were treated with a supplement at...
Oral bacteria and odontogenic oral infections are responsible for a high portion of cases with infective endocarditis. Hence, health in patients congenital heart disease (CHD) gains particular importance. This case-control study compared the status 112 adults CHD 168 healthy control subjects. In addition, patient group was stratified according to complexity defect recommendation antibiotic prophylaxis during invasive dental procedures. Considering caries experience, significantly lower mean...
Abstract Objectives Evaluation of cumulative survival and complication rate monolithic lithium disilicate inlays partial crowns performed by supervised undergraduate students up to 8.3 years clinical service. Materials methods In this retrospective study 143 posterior restorations (IPS e.max Press) were examined according the FDI criteria. A standardised questionnaire was used determine patient satisfaction. The aesthetic outcome evaluated dentists dental technicians using intraoral...
While HA is present naturally in periodontal tissues, its molecular weight can vary widely vivo. The objective of this study was to directly compare the biological reactions ligament cells four distinct weights hyaluronic acid (HA).Immortalized human (PDL-hTERT) were cultured for 21 days culture medium alone (control) or enriched with osteogenic supplements (OS group). Other 4 experimental groups OS addition different (HMW, MMW, LMW, and ULMW). cell morphology examined daily. WST1 assays...
Neutrophil granulocytes have been proposed to play a major role in the mediation of periodontitis-associated tissue destruction. Their recruitment and activation are regulated by chemokine CXCL8. This study aimed delineate dependency CXCL8 expression gingival crevicular fluid (GCF) saliva on periodontal status, bacterial infection, smoking, patients with periodontitis.The cohort comprised 279 subjects untreated periodontitis. Probing pocket depth (PPD), recession, bleeding probing (BOP),...
To determine the ultrastructural changes of titanium surfaces dental implants induced by tip periodontal probes.A total 40 samples smooth and rough were randomly assigned for treatment with metal or plastic probes under application angles 20° 60°. Titanium have been evaluated CLSM prior following to experimental probing determining various standardized 2D 3D roughness parameters.The average profile surface (Ra Sa) showed no significant difference between treated untreated on areas...
ABSTRACT Objective To investigate the association between interleukin‐8 (IL‐8) levels in gingival crevicular fluid (GCF) and total oral (TOF) responsiveness to steps 1 2 of periodontal therapy. Materials Methods One‐hundred fifty‐nine patients affected by periodontitis received At baseline, TOF GCF samples were collected analysed for IL‐8 (Il‐8 /IL‐8 ) using flow cytometry. Therapy outcomes relative proportions residual pockets (PPD%), pocket closure (PC) rates probing depth (PPD)...
ABSTRACT Aim To analyse whether some selected inflammatory biomarkers collected from venous blood and gingival crevicular fluid (GCF) were associated with the outcome of non‐surgical periodontal therapy. Materials Methods Two‐hundred nine patients affected by periodontitis enrolled in study, who had undergone steps I II therapy as well a re‐instrumentation (NSRI) pockets after 6 months. Serum (SE), plasma (PL) GCF samples quantitatively analysed for following biomarkers: active matrix...
Oxidative stress (OS) is a common feature of many inflammatory diseases, oral pathologies, and aging processes. The impact OS on periodontal ligament cells (PDLCs) in relation to including has been investigated different studies. However, its orthodontic tooth movement (OTM) remains poorly understood. This study used an vitro model with human PDLCs previously exposed H2O2 investigate the effects under static compressive force which simulated conditions OTM. Human were treated varying...