A5017053144- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Cardiovascular Issues in Pregnancy
- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Pulmonary Hypertension Research and Treatments
- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Medical Practices and Rehabilitation
- Cardiac pacing and defibrillation studies
- Cardiac Arrest and Resuscitation
- Coronary Artery Anomalies
- Infective Endocarditis Diagnosis and Management
- Congenital Diaphragmatic Hernia Studies
- Cardiac Health and Mental Health
- Cardiac Arrhythmias and Treatments
- Aortic Disease and Treatment Approaches
- Tracheal and airway disorders
- Cardiovascular Effects of Exercise
- Oral microbiology and periodontitis research
- Obesity, Physical Activity, Diet
- Streptococcal Infections and Treatments
- Nutrition and Health in Aging
- COVID-19 and Mental Health
- Connective tissue disorders research
University of Vienna
2021-2025
Deutsches Herzzentrum München
2016-2024
Technical University of Munich
2017-2024
München Klinik
2016-2022
German Centre for Cardiovascular Research
2021
Deutsches Herzzentrum der Charité
2016-2019
St. George's University
2018
As a result of improved surgical and therapeutical management, more than 90% patients with congenital heart disease (CHD) reach adulthood. However, the natural course CHD is complicated by noncardiac medical problems. Aim study was to evaluate comorbidities in contemporary cohort adults (ACHD).In tertiary care center for ACHD, 821 consecutive patients, admitted outpatient clinic, were evaluated clinically relevant comorbidities.The consecutively included (age: range, 15-80 years; 56% female)...
Aim The Fontan circulation is highly dependent on ventilation, improving pulmonary blood flow and cardiac output. A reduced ventilatory function reported in these patients. extent of this impairment its relation to exercise capacity quality life unknown objective study. Methods This multicenter retrospective/cross-sectional study included 232 patients (140 females, age 25.6 ± 10.8 years) after palliation (19.8% atrioventricular connection; 20.3% atriopulmonary 59.9% total cavopulmonary...
Introduction: Pulmonary hypertension (PH) is a common complication in patients with congenital heart disease (CHD), aggravating the natural, post-operative, or post-interventional course of underlying anomaly. The various CHDs differ substantially characteristics, functionality, and clinical outcomes among each other compared diseases pulmonary hypertension. Objective: To describe current management strategies for adults PH relation to different types CHD based on real-world data. Methods...
Due to advances in the diagnosis and treatment of congenital heart disease (CHD), number adults who are surviving with (ACHD) is constantly growing. Until recently, psychological effects CHD had been widely neglected. Current research provides evidence for an increased risk emotional distress ACHD. The concept illness identity attempts explain how patients experience integrate their into identities. present study investigated relation clinical parameters functioning. Psychometric properties...
Since 1968, thousands of patients with a morphologically or functionally univentricular heart have been treated total cavopulmonary connection/Fontan operation. Because the resulting passive pulmonary perfusion, blood flow is assisted by pressure shift during respiration. Respiratory training known to improve exercise capacity and cardiopulmonary function. However, there are limited data on whether respiratory can also physical performance after Fontan surgery. The aim present study was...
Background: Due to the increase in survival rates for congenital heart disease (CHD) last decades, over 90% of patients today reach adulthood. Currently, there are more than 300,000 adults with CHD (ACHD) living Germany. They have an increased need specialized medical care, since almost all ACHD chronic and suffer from specific symptoms, risks, sequelae. Primary care physicians (PCPs) play a crucial role referring specialists or institutions. This cross-sectional study is intended clarify...
Background: The number of adults with congenital heart disease (ACHD) is steadily rising due to increased survival rate and improved medical resources. Accordingly, more than 330,000 ACHD are currently living in Germany. Almost all them require lifelong specialized follow-up for their chronic disease, often accompanied by residua, sequelae, or comorbidities. Primary care physicians (PCPs) a crucial factor directing patients specialists institutions, but despite efforts, the under low,...
Objective The present cross-sectional study investigated quality of life (QOL) in a large cohort German adults with congenital heart disease (ACHDs) association patient-related and clinical variables. Design Cross-sectional survey. Participants Between 2016 2019, representative sample 4014 various forms defect (CHD) was retrospectively analysed. Inclusion criteria were confirmed diagnosis CHD; participant aged 18 years older; necessary physical, cognitive language capabilities to complete...
In patients with congenital heart disease (CHD), there is little data on the diagnostic and prognostic relevance of hand grip strength (HGS) for clinical assignment, while in general population loss muscle mass an important risk factor cardiovascular which conversely associated morbidity all-cause mortality. This study aimed to assess degree dysfunction using HGS as a biomarker large group CHD who often develop dysfunction.In total, 385 (27.6±13.1 years, 43% female) were included assigned 5...
Objectives This study aimed to provide a perspective for the interpretation of exercise capacity (peakVO 2 ) in patients with repaired Tetralogy Fallot (patients rTOF) by describing course peakVO from aged 6–63 years. Methods A retrospective was performed between September 2001 and December 2016 German Heart Centre Munich, Germany, University Medical Groningen, Netherlands. total 1175 cardiopulmonary tests (CPETs) were collected 586 rTOF, 46% female. Maximal exertion verified using...
In Deutschland leben rund 200 000 Erwachsene mit angeborenen Herzfehlern, die sich nicht in Behandlung von zertifizierten Spezialisten befinden, obwohl den letzten Jahren entsprechende Versorgungsstrukturen flächendeckend geschaffen wurden 1 2. Für diese Patienten besteht eine unerhebliche medizinische Unterversorgung potenziellen Auswirkungen auf Morbidität und Mortalität.
Marfan syndrome (MFS) is a genetically determined multiorgan disease that leads to severe physiological and psychological impairments in adult life. Little consensus exists regarding quality of life (QOL) individuals with MFS. The present study sought investigate QOL representative cohort adults MFS.Patient-reported outcome measures from sample 102 MFS (39.3±13.1 years age; 40.2% female) were retrospectively analyzed compared those different congenital heart defects (CHD), at the German...
Background The respiratory benefits of muscle strength are well-known in heart-healthy populations, but recommendations and research often focus instead on aerobic fitness (peak oxygen uptake) or total activity. Independent thus may be underestimated, especially congenital heart disease where perceived dangers certain types exercise outweigh benefits. To assess whether it is plausible that pulmonary populations also apply disease, we simultaneously correlated these patients’ lung function...
Pulmonary arterial hypertension (PAH) is common in congenital heart disease (CHD). Because clinical-trial data on PAH associated with CHD (PAH-CHD) remain limited, registry the long-term course are essential. This analysis aimed to update information from COMPERA-CHD management strategies based real-world data.The prospective international pulmonary COMPERA has since 2007 enrolled more than 10,000 patients. a sub-registry for patients PAH-CHD.A total of 769 PAH-CHD 62 specialized centers 12...
A growing number of adults with congenital heart disease (ACHD) pose a particular challenge for health care systems across the world. Upon turning into 18 years, under German national system, ACHD patients are required to switch from pediatric an adult cardiologist or ACHD-certified provider. To date, reliable data investigating treatment situation in Germany not available.An online survey was conducted collaboration patient organizations address life and conditions provision Germany. were...
Oral bacteria and odontogenic oral infections are responsible for a high portion of cases with infective endocarditis. Hence, health in patients congenital heart disease (CHD) gains particular importance. This case-control study compared the status 112 adults CHD 168 healthy control subjects. In addition, patient group was stratified according to complexity defect recommendation antibiotic prophylaxis during invasive dental procedures. Considering caries experience, significantly lower mean...