A5014635820- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Environmental law and policy
- Cardiac Imaging and Diagnostics
- Aortic Disease and Treatment Approaches
- Legal Issues in South Africa
- International Environmental Law and Policies
- Cardiovascular Function and Risk Factors
- Human Rights and Development
- Medical History and Research
- Cardiovascular and Diving-Related Complications
- Coronary Interventions and Diagnostics
- Congenital Heart Disease Studies
- Medical and Health Sciences Research
- Cardiac Arrhythmias and Treatments
- Historical Medical Research and Treatments
- Pulmonary Hypertension Research and Treatments
- Cardiac Structural Anomalies and Repair
- International Maritime Law Issues
- Global Peace and Security Dynamics
- Climate Change, Adaptation, Migration
- Cardiac pacing and defibrillation studies
- Medicine and Dermatology Studies History
- Climate Change Policy and Economics
- Syphilis Diagnosis and Treatment
Heart and Diabetes Center North Rhine-Westphalia
2014-2025
Bielefeld University
2025
University of Southampton
2021-2024
University of the Western Cape
2012-2021
Ruhr University Bochum
2008-2018
Groote Schuur Hospital
2018
University of Cape Town
2018
North-West University
2010-2017
Erasmus MC
2016
Werner-Wicker-Klinik
2015
Pulmonary hypertension (PH) is hemodynamically classified as pre-capillary (as seen in idiopathic pulmonary arterial [IPAH]) or post-capillary heart failure with preserved ejection fraction [HFpEF]). Overlaps between these conditions exist. Some patients present risk factors for left disease but PH, whereas HFpEF may have combined pre- and PH. This study sought to further characterize similarities differences among patient populations either PH-HFpEF IPAH. We used registry data analyze...
The term idiopathic pulmonary arterial hypertension (IPAH) is used to categorize patients with pre-capillary of unknown origin. There considerable variability in the clinical presentation these patients.Using data from Comparative, Prospective Registry Newly Initiated Therapies for Pulmonary Hypertension, we performed a cluster analysis 841 IPAH based on age, sex, diffusion capacity lung carbon monoxide (DLCO; <45% vs ≥45% predicted), smoking status, and presence comorbidities (obesity,...
New-onset conduction disturbances still represent a considerable problem after transcatheter aortic valve implantation (TAVI). The aim of this study was to identify calcification patterns with an elevated risk for permanent pacemaker (PPI) TAVI and investigate underlying mechanisms in ex vivo setting. One hundred sixty-two patients who underwent the Edwards SAPIEN XT® or Medtronic CoreValve® at our institution were analysed. calcium load device landing zone quantified 3mensio®, PPI...
AimsCalcification of the device landing zone is linked to paravalvular regurgitation after transcatheter aortic valve implantation (TAVI). The mechanisms remain incompletely understood and performance next-generation heart valves (THV) has not been investigated. We evaluated impact calcification patterns on residual (AR) TAVI with different THV in patients severe stenosis.
Echocardiographic speckle tracking or two-dimensional (2D) strain analysis is a new tool to assess myocardial function. This prospective controlled study evaluates systolic right ventricular (RV) function by 2D in adult patients with atrial septal defect (ASD) before and 3 months after percutaneous closure. Assessment of global longitudinal (GLS), rate (GLSR), regional peak (PSS) ventricle was performed 33 ASD patients. The data were compared those from 34 age-matched adults patent foramen...
Drug Prescribing for Patients with Chronic Kidney Disease in General Practice: a Cross-Sectional Study
Percutaneous closure of atrial septal defects is well established in children and adults has been found to improve symptoms positively influence right-heart remodeling. The aim this study was evaluate the efficacy long-term outcome adult patients older than 60 years.The population comprised 96 age group 84 years. performed effectively all patients. Functional capacity according New York Heart Association functional class peak oxygen uptake (VO(2)max) cardiopulmonary exercise testing improved...
AimTo investigate the putative modifying effect of dual antiplatelet therapy (DAPT) use on incidence stent thrombosis at 3 years in patients randomized to Endeavor zotarolimus-eluting (E-ZES) or Cypher sirolimus-eluting (C-SES).
Introduction: Pulmonary hypertension (PH) is a common complication in patients with congenital heart disease (CHD), aggravating the natural, post-operative, or post-interventional course of underlying anomaly. The various CHDs differ substantially characteristics, functionality, and clinical outcomes among each other compared diseases pulmonary hypertension. Objective: To describe current management strategies for adults PH relation to different types CHD based on real-world data. Methods...
Abstract Background Impaired renal function can increase cardiac troponin levels due to reduced elimination, potentially affecting its diagnostic utility. Limited data exist on high-sensitivity I (hs-cTnI) kinetics after surgery relative function. This study evaluates how impaired influences hs-cTnI following surgery, distinguishing between patients with and without postoperative myocardial infarction (PMI). Methods We conducted a retrospective analysis of adult who underwent elective at our...
Ebstein's anomaly is frequently associated with interatrial communications. In patients severe tricuspid regurgitation standard treatment the surgical repair or replacement of valve and patch closure atrial septal defect. We sought to evaluate feasibility short-term outcome interventional device communications in Ebstein mild moderate various degrees clinical symptoms. this case series 9 could be performed safely 8 improved their exercise capacity condition. However, need selected carefully...