A5017764831- Congenital Heart Disease Studies
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Coronary Artery Anomalies
- Cardiovascular Issues in Pregnancy
- Tracheal and airway disorders
- Cardiac Arrhythmias and Treatments
- Congenital Diaphragmatic Hernia Studies
- Cardiovascular Effects of Exercise
- Cardiac pacing and defibrillation studies
- Mechanical Circulatory Support Devices
- Heart Failure Treatment and Management
- Cardiovascular and Diving-Related Complications
- Cardiovascular Conditions and Treatments
- Cardiovascular and exercise physiology
- Cardiac Arrest and Resuscitation
- Vascular anomalies and interventions
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Renal and Vascular Pathologies
- Heart Rate Variability and Autonomic Control
- Cardiac Imaging and Diagnostics
- Respiratory Support and Mechanisms
Deutsches Herzzentrum München
2016-2025
Technical University of Munich
2016-2025
Deutsches Herzzentrum der Charité
2010-2024
358 (Finland)
2023
Faculty of 1000 (United States)
2023
German Centre for Cardiovascular Research
2022
St. George's University
2018
Rigshospitalet
2018
München Klinik
1999-2016
Universität Innsbruck
1960-2015
previous studies have established an association between exercise intolerance and increased morbidity mortality in congenital heart disease patients. We aimed to clarify if is associated with poor outcome Fontan patients identify risk factors for mortality, transplantation, cardiac-related hospitalization.a total of 321 (57% male, mean age 20.9 ± 8.6 years) who underwent cardiopulmonary testing (CPET) at four major European centres 1997 2008 were included. During a median follow-up 21...
Dysfunction of valved conduits in the right ventricular outflow tract (RVOT) limits durability and enforces repeated surgical interventions. We report on our combined two-centre experience with percutaneous pulmonary valve implantation (PPVI). One hundred two patients RVOT dysfunction [median weight: 63 kg (54.2–75.9 kg), median age: 21.5 years (16.2–30.1 years), diagnoses: TOF/PA 61, TAC 14, TGA 9, other 10, AoS post-Ross-OP 8] were scheduled for PPVI since December 2006. Percutaneous was...
Previous studies have shown that older Fontan patients and those with an underlying morphologically right ventricle lower exercise capacity. We sought to assess the natural history of capacity after operation in individual patients, identify factors influencing rate decrease over time.We studied, longitudinally, 53 cardiopulmonary tests (average 3.2 +/- 1.1 for each patient). Age at first test was 14 6 years. Time intervals between ranged from 1 16 years (average, 7.7 4.0 years). The...
The aim of this study is to compare self-reported health-related quality-of-life (HRQoL) with the objective exercise performance in patients congenital heart disease (CHD) according diagnosis. 564 (255 females, 14–73 years) various CHD (62 shunt, 66 left obstruction, 33 PS/PR, 47 Ebstein, 96 Fallot, 98 TGA after atrial switch, 38 other TGA, 31 Fontan, 32 palliated/native cyanotic, 61 others) and a group 53 healthy controls (18 14–57 completed QoL questionnaire (SF-36) performed...
AimsWe compared flow and wall shear stress (WSS) patterns in the ascending aorta of individuals with either bicuspid aortic valve (BAV) or tricuspid (TAV) using four-dimensional cardiovascular magnetic resonance (4D-CMR). BAV are known to be associated dilation dissection aorta. However, cause vessel disease patients BAVs is unknown. Inborn connective tissue also secondary increased WSS because altered blood discussed as causes for can estimated non-invasively by 4D-CMR.
AimsPatients with congenital heart disease usually show diminished exercise capacity and quality of life. However, there is only little information about daily activity, a marker for lifestyle, capacity, the prevention arteriosclerosis. This study investigated life, their interaction univentricular physiology after total cavopulmonary connection (TCPC).
<h3></h3> The European Paediatric Pulmonary Vascular Disease (PVD) Network is a registered, non-profit organisation that strives to define and develop effective, innovative diagnostic methods treatment options in all forms of paediatric pulmonary hypertensive vascular disease, including specific such as arterial hypertension (PAH)-congenital heart (PH) associated with bronchopulmonary dysplasia, persistent PH the newborn, related cardiac dysfunction. <h3>Methods</h3> writing group members...
This study aims to evaluate the clinical outcome following total cavopulmonary connection (TCPC) and identify factors affecting early late outcome.Between May 1994 March 2015, 434 patients underwent TCPC with 50 lateral tunnels 374 extracardiac conduits. The outcome, exercise capacity liver examination results were retrospectively reviewed.Thirty-day survival was 98.2%, estimated rate at 15 years 92.3%. Freedom from tachyarrhythmia 91.0%. Other morbidities included bradyarrhythmia in 17,...
Abstract OBJECTIVES We aimed to determine the incidence of postoperative complete atrioventricular block, time recovery or permanent pacemaker implantation, and predictors for block after congenital heart surgery. METHODS Patients who underwent open surgery from January 2001 2024 were analyzed identified using a logistic regression model. RESULTS Among 9765 surgeries, 333 (3.4%) complicated by 193 patients (1.9%) implantation. The highest rates found in repair congenitally corrected...
This study aimed to evaluate the relationship between pulmonary artery size and venovenous collaterals during staged single ventricle reconstruction. Patients who underwent Fontan palliation 2003 2023 were reviewed. The index development of was determined. Furthermore, impact on in-hospital morbidities after procedure evaluated. A total 377 patients included. Median age at bidirectional cavopulmonary shunt connection 4.2 (3.3-6.2) months 2.1 (1.7-2.6) years, respectively. Venovenous observed...
To investigate aortic dimensions in women with Turner syndrome (TS) relation to valve morphology, blood pressure, karyotype, and clinical characteristics.
Pulmonary hypertension (PH) is a condition of multiple aetiologies with underestimated prevalence and incidence. Indeed, despite access to modern therapies, pulmonary hypertensive vascular disease (PHVD) remains progressive, usually life-limiting condition, severely impacting on the patients' well-being. We herein provide practical, expert consensus recommendations initial diagnostic work-up, clinical management follow-up children adolescents PH/PHVD, including algorithm. The major topics...
Background: Percutaneous pulmonary valve implantation (PPVI) has become an important treatment of right ventricular outflow tract dysfunction. Studies directly comparing the long-term outcome PPVI with Melody to surgical replacement (SPVR) are lacking. Methods: All patients treated and SPVR between January 2006 December 2018 in our center were enrolled into a database investigated standard follow-up protocol. The current study compares outcomes means survival, reinterventions, infectious...
<b>Objectives:</b> To compare self reported quality of life with measured exercise capacity in patients congenital heart disease. <b>Design:</b> Prospective cross sectional clinical study <b>Setting:</b> Tertiary referral centre for cardiology <b>Patients and methods:</b> 149 (60 female, 14–60 years old) various defects completed a health related questionnaire (medical outcomes 36 item short form). Then they performed cardiopulmonary test on bicycle sitting position. <b>Results:</b> Peak...