A5034373000- Lipid metabolism and disorders
- Liver Disease Diagnosis and Treatment
- Growth Hormone and Insulin-like Growth Factors
- Diet, Metabolism, and Disease
Islamic Azad University, Tehran
2022-2023
Background: Considering the role of visfatin in nonalcoholic fatty liver disease (NAFLD), a growing global epidemic, this article explores potential association between gene (NAMPT) and NAFLD. Methods: We used PCR-restriction fragment length polymorphism method to genotype rs1319501 promoter variant NAMPT 154 patients with biopsy-proven NAFLD 158 controls case–control genetic study. Results: The 'CC+TC' comparison 'TT' occurred less frequently cases than controls, difference remained...
Nonalcoholic fatty liver disease (NAFLD) is an emerging global chronic encompassing a wide spectrum of disorders ranging from simple steatosis to nonalcoholic steatohepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. Considering the strong association between NAFLD insulin resistance, vital role insulin-like growth factor 1 (IGF1) in IR, we hypothesized that IGF1 gene polymorphism might be associated with NAFLD.A total 302 subjects, including 149 patients biopsy-proven 153...