About
Contact & Profiles
A5068802171
Research Areas
- Monoclonal and Polyclonal Antibodies Research
- Protein Structure and Dynamics
- Neuropeptides and Animal Physiology
- RNA and protein synthesis mechanisms
- Lipid Membrane Structure and Behavior
- Cancer-related gene regulation
- Peptidase Inhibition and Analysis
- Radiopharmaceutical Chemistry and Applications
- Glycosylation and Glycoproteins Research
- Ubiquitin and proteasome pathways
- Carbohydrate Chemistry and Synthesis
- Bacterial Infections and Vaccines
University of Virginia
2022-2024
10.1016/j.bpj.2023.11.1875
article
EN
Biophysical Journal
2024-02-01
N -glycosylation is a common posttranslational modification of secreted proteins in eukaryotes. This targets asparagine residues within the consensus sequence, N–X–S/T. While this sequence required for glycosylation, initial transfer high-mannose glycan by oligosaccharyl transferases A or B (OST-A OST-B) can lead to incomplete occupancy at given site. Factors that determine extent are not well understood, and understanding them may provide insight into function these important enzymes. Here,...
10.1073/pnas.2202992119
article
EN
cc-by-nc-nd
Proceedings of the National Academy of Sciences
2022-10-17
10.1016/j.bpj.2021.11.446
article
EN
publisher-specific-oa
Biophysical Journal
2022-02-01
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