A5035890991- Genomics and Phylogenetic Studies
- Microbial Natural Products and Biosynthesis
- Plant Pathogens and Fungal Diseases
- Fungal Biology and Applications
- Genetic diversity and population structure
- Plant-Microbe Interactions and Immunity
- Plant and Fungal Species Descriptions
- Identification and Quantification in Food
- Medicinal Plant Extracts Effects
- Natural product bioactivities and synthesis
- Plant Disease Resistance and Genetics
- Plant and animal studies
- Molecular Biology Techniques and Applications
- Lichen and fungal ecology
- Mycorrhizal Fungi and Plant Interactions
- Plant Parasitism and Resistance
- Nematode management and characterization studies
- Phytochemical Studies and Bioactivities
- Aquatic Invertebrate Ecology and Behavior
- Silymarin and Mushroom Poisoning
- Insect and Arachnid Ecology and Behavior
- Plant and fungal interactions
- Marine Biology and Ecology Research
- Plant biochemistry and biosynthesis
- Ginseng Biological Effects and Applications
National Institute of Biological Resources
2016-2025
Ministry of Environment
2024
Hallym University
2023
Seoul National University Hospital
2023
Seoul National University
2022
Abstract Cytoplasmic chloroplast (cp) genomes and nuclear ribosomal DNA (nR) are the primary sequences used to understand plant diversity evolution. We introduce a high-throughput method simultaneously obtain complete cp nR using Illumina platform whole-genome sequence. applied 30 rice specimens belonging nine Oryza species. Concurrent phylogenomic analysis of several same AA genome species provides insight into evolution domestication cultivated rice, clarifying three ambiguous but...
There are three main dietary groups in mammals: carnivores, omnivores, and herbivores. Currently, there is limited comparative genomics insight into the evolution of specializations mammals. Due to recent advances sequencing technologies, we were able perform in-depth whole genome analyses representatives these groups. We investigated carnivory by comparing 18 representative genomes from across Mammalia with carnivorous, omnivorous, herbivorous specializations, focusing on Felidae (domestic...
Background The freshwater mussel Cristaria plicata (Bivalvia: Eulamellibranchia: Unionidae), is an economically important species in molluscan aquaculture due to its use pearl farming. have been listed as endangered South Korea the loss of natural habitats caused by anthropogenic activities. decreasing population and a lack genomic information on concerning for environmentalists conservationists. In this study, we conducted de novo transcriptome sequencing annotation analysis C. using...
Because most efforts to understand the molecular mechanisms underpinning fungal pathogenicity have focused on studying function and role of individual genes, relatively little is known about how transcriptional machineries globally regulate coordinate expression a large group genes involved in pathogenesis. Using quantitative real-time PCR, we analyzed patterns 206 transcription factor (TF) rice blast fungus Magnaporthe oryzae under 32 conditions, including multiple infection-related...
Three Apiaceae species Ledebouriella seseloides, Peucedanum japonicum, and Glehnia littoralis are used as Asian herbal medicines, with the confusingly similar common name "Bang-poong". We characterized complete chloroplast (cp) genomes 45S nuclear ribosomal DNA (45S nrDNA) sequences of two accessions for each species. The cp G. littoralis, L. P. japonicum were 147,467, 147,830, 164,633 bp, respectively. Compared to other species, genome had a huge inverted repeat expansion segmental...
Mulberry (Morus alba L.) is used in traditional Chinese medicine and the sole food source of silkworm. Here, 21 cDNAs encoding phenylpropanoid biosynthetic genes triterpene were isolated from mulberry. The expression levels involved these pathways accumulation rutin, betulin, betulinic acid, important secondary metabolites, investigated different plant organs. Most highly expressed leaves and/or fruit, most downregulated during fruit ripening. rutin was more than fivefold higher other...
Roots of Glehnia littoralis have been used to heal stroke as a traditional medicine. Even though many studies on this plant conducted, the secondary metabolites produced by its endophytes and their bioactivities not investigated thus far. Therefore, new meroditerpenoid named sartorypyrone E (1) eight known compounds (2-9) were isolated from extracts cultured Neosartorya fischeri JS0553, an endophyte G. littoralis. The identified using spectroscopic methods chemical reaction, based comparison...
Significance We sequenced and analyzed the genome of endangered whale shark, largest fish on Earth, compared it to genomes 84 other species ranging from yeast humans. found strong scaling relationships between genomic physiological features. posit that these relationships, some which were remarkably general, mold integrate metabolic constraints pertaining body size ecological variables such as temperature depth. Unexpectedly, we also neural genes is strongly correlated with lifespan in most...
Six new isochroman derivatives (annulohypoxylomans A–C, 1–3; annulohypoxylomanols A and B, 6 7; annulohypoxyloside, 8), an isocoumarin (annulohypoxylomarin A, 4), azaphilone derivative (xylariphilone, 5) were isolated from ethyl acetate extract derived cultures of the endophytic fungus JS540 found in leaves Zizania caduciflora. The strain was identified as Annulohypoxylon truncatum. structures compounds elucidated by one- two-dimensional nuclear magnetic resonance mass spectrometry...
Ambrosia fungi are well-known for their symbiotic interactions with ambrosia beetles, acting as a sole food source of larvae and adult beetles. As first step to reveal these interactions, extensive survey on the fungal symbionts beetles dwelling in Korea. Eight species isolated from 15 beetle were not known presence Seven belonged two orders Ascomycota; Microascales (Ambrosiella beaveri, A. catenulate, roeperi) Ophiostomatales (Leptographium verrucosum, Raffaelea cyclorhipidii, R. subfusca,...
Vespa mandarinia found in the forests of East Asia, including Korea, occupies highest rank arthropod food web within its geographical range. It serves as a source nutrition form amino acid mixture and is listed threatened species, although no conservation measures have been implemented. Here, we performed de novo assembly V. transcriptome by Illumina HiSeq 4000 sequencing. Over 60 million raw reads 59,184,811 clean were obtained. After assembly, total 66,837 unigenes clustered, 40,887,...
The lichen-forming fungus Cladonia metacorallifera strain KoLRI002260 is capable of producing a number secondary metabolites, including usnic, didymic, and squamatic acids, which have antitumor, antioxidant, antibiotic activities. draft genome assembly has size 36,682,060 bp, with G+C content 44.91%, consists 30 scaffolds.
Glutamate neurotoxicity has been implicated in neuronal death both acute CNS injury and chronic neurodegenerative diseases. Five unique cyclic depsipeptides with neuroprotective activity, colletotrichamides A-E (1-5), were isolated from cultures of a halophyte Suaeda japonica-associated fungus, Colletotrichum gloeosporioides JS419. Spectroscopic analysis revealed that they glycosylated lipodepsipeptides. Their relative configurations determined by ROESY J-based configuration analysis,...
The lichen-forming fungus Cladonia macilenta strain KoLRI003786 is capable of producing an acetylcholinesterase inhibitor, biruloquinone, which effectively prevents neurodegeneration in Alzheimer's disease. Laying the foundation to unravel biruloquinone biosynthetic pathway, we present 37.11-Mb draft genome sequence KoLRI003786.
Valeriana fauriei is commonly used in the treatment of cardiovascular diseases many countries. Several constituents with various pharmacological properties are present roots species. Although researches on V. have been done since a long time, further studies discipline make limit due to inadequate genomic information. Hence, Illumina HiSeq 2500 system was conducted obtain transcriptome data from shoot and root fauriei.
Colletotrichum sp. JS-0367 was isolated from Morus alba (mulberry), identified, and cultured on a large scale for chemical investigation. One new anthraquinone (1) three known anthraquinones (2–4) were identified using spectroscopic methods including 1D/2D-NMR HRESIMS. Although the neuroprotective effects of some have been reported, biological activities four in this study not reported. Therefore, these compounds determined against murine hippocampal HT22 cell death induced by glutamate....
ABSTRACT Here we report a draft genome sequence of Caloplaca flavorubescens strain KoLRI002931, isolated from the bark gingko tree at Mt. Deogyu, Muju, South Korea. The is 34,455,815 bp, with GC content 41.89%, consisting 36 scaffolds.
Mastoparans from the venom of social wasps have attracted considerable attention as effective antibiotic candidates. In this study, mastoparan V1 (MP-V1) Vespula vulgaris was first disclosed to a peptide amino acid sequence distinct typical mastoparans and its biochemical properties antimicrobial effects were compared with those MP-L, -X(V) -B. Circular dichroism (CD) spectroscopy revealed that MP-V1 form more stable α-helical conformations in lipid membrane-like environments than MP-L...
Satsuma myomphala is critically endangered through loss of natural habitats, predation by enemies, and indiscriminate collection. It a protected species in Korea but lacks genomic resources for an understanding varied functional processes attributable to evolutionary success under habitats. For assessing the genetic information S. myomphala, we performed first time, de novo transcriptome sequencing annotation expressed sequences using Illumina Next-Generation Sequencing (NGS) platform...
Glutamate toxicity has been implicated in neuronal cell death both acute CNS injury and chronic diseases. In our search for neuroprotective agents obtained from natural sources that inhibit glutamate toxicity, an endophytic fungus, Fusarium solani JS-0169 isolated the leaves of Morus alba, was found to show potent inhibitory activity. Chemical investigation cultures fungus afforded isolation six compounds, including one new γ-pyrone (1), a known γ-pyrone, fusarester D (2), four...
The Lycaenidae butterflies, Protantigius superans and Spindasis takanosis, are endangered insects in Korea known for their symbiotic association with ants. However, necessary genomic transcriptomics data lacking these species, limiting conservation efforts. In this study, the P. S. takanosis transcriptomes were deciphered using Illumina HiSeq 2500 sequencing. transcriptome included a total of 254,340,693 245,110,582 clean reads assembled into 159,074 170,449 contigs 107,950 121,140 unigenes,...
An aquatic gastropod belonging to the family Neritidae, Clithon retropictus is listed as an endangered class II species in South Korea. The lack of information on its genomic background limits ability obtain functional data resources and inhibits informed conservation planning for this species. In present study, transcriptomic sequencing de novo assembly C. generated a total 241,696,750 high-quality reads. These assembled 282,838 unigenes with mean N50 lengths 736.9 1201 base pairs,...
Fungal endophytes have attracted attention due to their functional diversity. Secondary metabolites produced by Pestalotiopsis sydowiana from a halophyte, Phragmites communis Trinus, were investigated. Eleven compounds, including four penicillide derivatives (1-4) and seven α-pyrone analogues (5-10) isolated cultures of P. sydowiana. The compounds identified based on spectroscopic data. inhibitory activities against the 20S proteasome evaluated. Compounds 1-3, 5, 9-10 showed modest...