Coronal plane alignment of the knee (CPAK) has recently been proposed as a simple and universal classification system to determine suitability particular phenotype specific strategy for replacement surgery. Although racial differences may affect alignment, there are no reports on distribution this system. We aimed clarify CPAK in patients with osteoarthritis who underwent total arthroplasty (TKA) Japan. Consecutive primary TKA were analyzed retrospectively. The knees categorized according...

Countermeasures against the spread of COVID-19 have become an urgent issue in educational settings, where many group activities are necessary. Educators key to preventing settings. Infection prevention behavior requires comprehensive and complex measures such as self-restraint. disinfection care, hand washing, wearing masks recommendation implementation vaccination. Improvement knowledge, skills, preventive actions educators vis-à-vis could allow for continued provision services while...

Model-assisted designs have garnered significant attention in recent years due to their high accuracy identifying the maximum tolerated dose (MTD) and operational simplicity. To identify MTD, they employ estimated limiting toxicity (DLT) probabilities via isotonic regression with pool-adjacent violators algorithm (PAVA) after trials been completed. PAVA adjusts independently DLT Bayesian binomial model at each level using posterior variances ensure monotonicity that increases dose. However,...

For analyzing square tables having same row and column classifications, analysts are often interested in whether or not the relation between variables is symmetric asymmetric regarding main-diagonal cells of table. However, for dataset grip strength test, may be them anti-diagonal cells, instead cells. This study proposes anti-diagonals-parameter symmetry model that represents structure Furthermore, this provides a separation anti-symmetry using an orthogonal test statistic model. shows...

For analyzing contingency tables, we are usually interested in whether or not the independence model holds. On other hand, for analysis of square having structure symmetry asymmetry with respect to main diagonals cells This study proposes a generalized sum-asymmetry including exponential and relative sum-symmetry models. indicates that cumulative probability sum classes row column variables is s within upper right cell table, exponentially higher than lower left cell. Additionally, this...

Abstract Ferroptosis is a form of regulated cell death that induced by inhibiting glutathione peroxidase 4 (GPX4), which eliminates lipid peroxidation. induction influenced the environment. However, cellular states altering ferroptosis susceptibility remain largely unknown. We found melanoma lines became resistant to as density increased. Comparative transcriptome and metabolome analyses revealed density‐dependent resistance was coupled with shift toward lipogenic phenotype accompanied...

Abstract For the analysis of square contingency tables with same row and column ordinal classifications, this study proposes an index for measuring degree departure from symmetry model using new cumulative probabilities. The proposed is constructed based on Cressie Read’s power divergence, or weighted average Patil Taillie’s diversity index. This derives a plug-in estimator approximate confidence interval expected to reduce bias more than existing index, even when sample size not large....

Abstract For the analysis of square contingency tables with ordinal classifications, marginal homogeneity (MH) model is one important models. Some measures for analyzing degree departure from MH have been proposed. This study proposes a new measure using continuation odds. Continuation odds may be considered as discrete time hazard. The proposed expressed in form Cressie-Read’s power-divergence (including Kullback-Leibler divergence) or Patil and Taillie’s diversity index Shannon entropy)....

Potential impairment of exercise capacity is prevalent even in patients undergoing hemodialysis without frailty. Cardiopulmonary testing (CPET) can detect physiological reserves such as cardiopulmonary, muscle, and autonomic function. We hypothesized that these indices could accurately determine the prognosis on analyzed them based their relationship to

For square contingency tables with ordered categories, the present article proposes a two-dimensional measure vector existing indexes to elements that can simultaneously analyze degree of asymmetry and directionality for two kinds asymmetries. The proposed would be useful asymmetry, while distinguishing Also, visually comparing degrees in several using confidence region.

For square contingency tables with ordered categories, Iki, Tahata and Tomizawa [12] considered the ridit score type quasi-symmetry model. The present paper proposes an extension of that model having one more parameter. Using proposed model,

The study identifies appropriate risk expressions by healthcare professionals in communicating the risks of driving-impairing medicine to patients, gauging changed patient behavior, preventing traffic accidents due drugs, and improving drug adherence.An online questionnaire survey was conducted on participants' perception driving-related risks, awareness, as well reports professionals' warning messages regarding drugs.Approximately 80 % participants were aware effects pharmaceutical drugs...

Twelve one-day-old chicks were experimentally inoculated with Chlamydia psittaci derived from turkeys. Acute chlamydial septicemic lesions induced by the inoculation into air sac and trachea. No produced esophageal injection. Clinically, affected showed emaciation mouth breathing, inactive while some birds died. Grossly, they had hepatomegaly, splenomegaly airsacculitis. Histopathologically, fibrinopurulent airsacculitis, pneumonia bronchitis, multiple fibrinous serositis in hepatic splenic...

Hypermobile lateral meniscus is difficult to diagnose with imaging due its absence of tears or anomalies. We aimed clarify the accuracy preoperative diagnosis using magnetic resonance (MRI).The MRI status posterosuperior popliteomeniscal fascicle (sPMF), anteroinferior (iPMF), and popliteal hiatus were examined retrospectively on sagittal images in hypermobile group (n = 22) an age- gender-matched control 44). These statuses evaluated by a logistic regression analysis assess their degree...

Objective: This study aimed to determine the usefulness and effects of a pictogram for alerting patients about drugs that affect driving in order prevent traffic injury maintain good adherence.Method: The participants comprised 600 men women aged 20–79 (49.58 ± 16.21) years, registered with an Internet research company. All were licensed drive car taking prescribed medication. outcome measures were: 1) awareness existing pictogram, 2) perceived risk after viewing 3) 4) medication-taking...

The cause of spasmodic dysphonia, a dystonic disorder the larynx, remains unclear. Recently, TAFII250, TATA-box binding protein associated factor, was suggested to be involved in dystonia parkinsonism. There is possibility that TAFII250 but little information available about expression laryngeal nervous system. In this study, we investigated localization rat system by immunohistochemistry. TAFII250-immunoreactivity detected nodose ganglion and superior cervical ganglion. these nuclei,...

Abstract Background A simple, non-quantitative, and cost-effective diagnostic tool would enable the diagnosis of flatfoot without need for specialized training. simple footprint assessment board that investigates which toe cord passes through from centre point heel to most lateral medial contour has been developed assess flatfoot. The purpose this study was verify validity a Methods Thirty-five consecutive patients with foot pain, injury, or any associated symptoms who underwent computed...

Summary In the existing decomposition theorem, sum-symmetry model holds if and only both exponential global symmetry models hold. However, this theorem does not satisfy asymptotic equivalence for test statistic. To address aforementioned gap, study establishes a in which weighted global-sum-symmetry The proposed satisfies We demonstrate advantages of by applying it to datasets comprising real data artificial data.

For square contingency tables, a double symmetry model having matrix structure that combines both and point was proposed. Also, an index which represents the degree of departure from However, this cannot simultaneously characterize symmetry. measuring symmetry, present paper proposes bivariate vector can

PurposeTo compare tomosynthesis and computed tomography (CT) for evaluating bone plug integration after anterior cruciate ligament (ACL) reconstruction with a bone–patellar tendon–bone (BPTB) graft.MethodsData of consecutive adult patients who underwent ACL BPTB were analyzed. Bone between the tunnel was evaluated by CT, which both performed 3 months postoperatively. The obtained data modalities reconstructed slice thickness 2 mm. Evaluation separately using coronal- sagittal-reconstructed...

Measures that represent the degree of departure from symmetry, global and conditional symmetry have been proposed to analyze square contingency tables. Additionally, a refined estimator measure has suggested. This study provides estimators measures for shows relationship between estimator. The can be obtained by second-order term in Taylor series expansion. Simulations studies demonstrate as sample size increases, approach true values faster than former estimators.