A5068447776- Radiation Therapy and Dosimetry
- Nuclear Physics and Applications
- Radiation Detection and Scintillator Technologies
- Medical Imaging Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Advanced Radiotherapy Techniques
- Graphite, nuclear technology, radiation studies
- Particle accelerators and beam dynamics
- Medical Imaging and Pathology Studies
- Radioactive Decay and Measurement Techniques
- Radioactivity and Radon Measurements
- Nuclear and radioactivity studies
- Advanced X-ray and CT Imaging
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Research Studies
- Peptidase Inhibition and Analysis
- Artificial Intelligence in Healthcare and Education
- CAR-T cell therapy research
- Time Series Analysis and Forecasting
- Context-Aware Activity Recognition Systems
- Particle Accelerators and Free-Electron Lasers
- Nonmelanoma Skin Cancer Studies
- Wireless Sensor Networks for Data Analysis
- Radiation Dose and Imaging
- Boron Compounds in Chemistry
Azienda USL di Bologna
2020-2023
Policlinico S.Orsola-Malpighi
2016-2023
University of Bologna
2014-2020
Abstract Background and aim High dose brachytherapy using a non sealed 188 Re-resin (Rhenium-SCT®, Oncobeta® GmbH, Munich, Germany) is treatment option for non-melanoma skin cancer (NMSC). The of this prospective study was to assess the efficacy safety single application Rhenium-SCT® in NMSC. Materials method Fifty consecutive patients (15F, 35 M, range age 56–97, mean 81) showing 60 histologically proven NMSCs were enrolled treated with between October 2017 January 2020. Lesions located on...
High-dose rate brachytherapy using a non-sealed 188 Rhenium resin (188 Re) is recently approved treatment option for non-melanoma skin cancer (NMSC). The goal to deliver personalized absorbed dose the deepest point of neoplastic infiltration corresponding minimal target dose. consists application Re-based over plastic foil placed on surface. However, there no planning tool assess Re activity needed treatment.The paper aims present novel Monte Carlo (MC)-based and calculation, experimentally...
Radiation protection (RP) in the use of medical cyclotrons involves many aspects both routine and for decommissioning a site. Guidelines site planning installation, as well RP assessment, are given international documents; however, latter typically offer analytic methods calculation shielding materials activation, approximate or idealised geometry set-ups. The availability Monte Carlo (MC) codes with accurate up-to-date libraries transport interaction neutrons charged particles at energies...
In the production of Positron Emission Tomography (PET) nuclides at a medical cyclotron facility [Formula: see text]Ar (T[Formula: text] = 109.34 m) is produced by activation air due to neutron flux, according text]Ar(n, text])[Formula: reaction. this work, we describe relatively inexpensive and readily reproducible methodology sampling that can be used for quantification during routine PET nuclides. We report results an extensive measurement campaign in bunker ducts ventilation system,...
During the operational life of a PET Cyclotron, concrete walls cyclotron vault are activated by secondary neutron flux interacting with rare earths and metals present in or reinforcement bars. For this reason when considering dismantling such accelerators, amount radioactive waste has to be evaluated advance identify any critical issues possible countermeasures taken define an optimum decommissioning strategy. The aim work is non-destructive situ measurement methodology for preliminary...
Background: In medical cyclotron facilities, 11C is produced according to the 14N(p,α)11C reaction and widely employed in studies of prostate brain cancers by Positron Emission Tomography. It known from literature that 11C-target assembly shows a reduction efficiency during time, meaning decrease activity at end bombardment. This effect might depend on aspects which are still not completely known. Objective: Possible causes loss performance were addressed Monte Carlo simulations. Methods:...
This work was aimed at characterizing and validating a very compact, USB-powered, CdZnTe detector for gamma-ray spectrometry applications in radiopharmacy. A GR1 model (by KromekTM, Sedgefield, UK) utilized. The calibrated energy efficiency. Samples of [18F]FDG [68Ga]-DOTANOC were measured to assess the detector's suitability radionuclidic purity measurements. resolution efficiency obtained are fully adequate quality control positron emission tomography radiopharmaceuticals. Results samples...
In road and railway tunnel excavation, personnel are exposed to natural radiation. Exposure can have varying degrees of significance, as naturally occurring radioactive material (NORM) content may vary by more than one order magnitude depending on local lithology and, far radon is concerned, also features distant bedrocks involved in convection. Radon exhalation build up the confined environment affected permeability rocks, which highly variable with lithology. Excavation methods well an...
Cyclotrons are one of the most important sources radionuclides used in biomedical applications. The production single-photon emission tomography techniques such as 123I, 67Ga, 201Tl, and 111In has been based for decades on cyclotrons, typically proton machines with an energy up to 30 MeV. extraordinary growth positron (PET) led development new models installation numerous accelerating protons range 10 20 These have main PET radionuclides, namely, 11C, 13N, 15O, above all, 18F. Recently,...
An innovative epidermal surface treatment based on 188Re has been recently developed for squamous cell carcinomas of the skin. The planning and delivery requires an accurate knowledge source activity thus proper calibration meters. However, reference sources purposes are not always available, as in case short-lived radionuclides. aim this work is to determine factors by comparison measurements with independently calibrated HPGe spectrometer. Calibration were experimentally determined two...
A correction to this paper has been published: https://doi.org/10.1007/s00259-021-05363-7