A5091226279- Proteoglycans and glycosaminoglycans research
- Education, Psychology, and Social Research
- Dendrimers and Hyperbranched Polymers
- Microbial Natural Products and Biosynthesis
- Glycosylation and Glycoproteins Research
- Taxation and Legal Issues
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Inflammatory mediators and NSAID effects
- Electrochemical Analysis and Applications
- Veterinary Equine Medical Research
- Fungal Biology and Applications
- Polysaccharides and Plant Cell Walls
- Monoclonal and Polyclonal Antibodies Research
- Analytical Methods in Pharmaceuticals
- Immune Response and Inflammation
- bioluminescence and chemiluminescence research
- Chemical Synthesis and Analysis
- Connective tissue disorders research
- Diatoms and Algae Research
- Protein purification and stability
- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- Radiation Effects and Dosimetry
- Chemical synthesis and alkaloids
- Radiation Therapy and Dosimetry
University of Pardubice
2018-2024
SUMMARY: The development of Streptomyces rimosus in submerged culture, a medium containing starch, glucose, ammonium sulphate, corn-steep liquor and calcium carbonate, takes place several phases which differ their morphological biochemical characteristics. starting phase is characterized by the logarithmic growth thick Gram-positive filaments primary mycelium. Nucleic acids respiratory enzymes are being synthesized during this free amino inorganic phosphorus almost completely used up. A...
Abstract A pilot plant unit for continuous cultivation of hyphaeforming micro‐organisms, providing a uniform flow velocity in fermentations on suspension media with massive growth mycelium, is described. For the maintenance aseptic conditions, over‐pressre air maintained whole equipment. This equipment has been used studies biosynthesis streptomycin. three‐stage fermentation proved most advantageous. The first stage serves multiplication inoculum; second and third formation antibiotic....
Purpose: Therapeutic thorax irradiation as an intervention in lung cancer has its limitations due to toxic effects leading pneumonitis and/or pulmonary fibrosis. It already been confirmed that hyaluronic acid (HA), extracellular matrix glycosaminoglycan, is involved inflammation disorders and wound healing tissue. We examined the after gamma of nanoparticles (HANPs) applied into prior a dose causing radiation-induced injuries (RIPI). Materials methods: Biocompatible HANPs were first used for...
Abstract During the biosynthetic production of chlortetracycline on a medium with sucrose, soy meal, corn steep extract, sodium chloride, ammonium sulphate, calcium carbonate and beet molasses, amount nucleic acids synthesized by culture maximum respiration is determined inorganic phosphate in original medium. Chlortetracycline does not start until all has been consumed. The adverse influence increased amounts upon more apparent flasks shaking machine than agitated aerated fermentation tanks...
Hyaluronic acid is an excellent biocompatible material for in vivo applications. Its ability to bind CD44, a cell receptor involved numerous biological processes, predetermines HA-based nanomaterials as unique carrier therapeutic and theranostic Although methods the synthesis of hyaluronic nanoparticles (HANPs) are available today, their low reproducibility wide size distribution hinder precise assessment effect on organism. A robust reproducible approach producing HANPs that meet strict...