A5011566546- Effects of Radiation Exposure
- Radiation Effects and Dosimetry
- Radiation Therapy and Dosimetry
- Carcinogens and Genotoxicity Assessment
- Genetic and Kidney Cyst Diseases
- Electrochemical sensors and biosensors
- Protist diversity and phylogeny
- Radiation Dose and Imaging
- Head and Neck Cancer Studies
- Spaceflight effects on biology
- Metabolism, Diabetes, and Cancer
- Neonatal Health and Biochemistry
- Radioactive contamination and transfer
- Cancer therapeutics and mechanisms
- Curcumin's Biomedical Applications
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lung Cancer Diagnosis and Treatment
- Renal and related cancers
- Pleural and Pulmonary Diseases
- Cancer Cells and Metastasis
- Biochemical effects in animals
- Fusion and Plasma Physics Studies
- Ultrasound and Hyperthermia Applications
- Alcoholism and Thiamine Deficiency
- Bone Tissue Engineering Materials
Stockholm University
2025
University of Defence
2018-2020
Abstract In previous RENEB interlaboratory comparisons based on the manual scoring of dicentric chromosomes, a tendency for systematic overestimation doses > 2.5 Gy was found. However, these exercises included only very few in high dose range, and they were heterogeneous terms radiation quality evaluation mode, comparable to limited extent. Here, this presumed deviation explored by investigating three Gy. Blood samples irradiated (2.56, 3.41 4.54 Gy) using 60 Co source sent 14 member...
Purpose: Therapeutic thorax irradiation as an intervention in lung cancer has its limitations due to toxic effects leading pneumonitis and/or pulmonary fibrosis. It already been confirmed that hyaluronic acid (HA), extracellular matrix glycosaminoglycan, is involved inflammation disorders and wound healing tissue. We examined the after gamma of nanoparticles (HANPs) applied into prior a dose causing radiation-induced injuries (RIPI). Materials methods: Biocompatible HANPs were first used for...
The increasing risk of radiation exposure underlines the need for novel radioprotective agents. Hence, a series 1-(2-hydroxyethyl)piperazine derivatives were designed and synthesized. Some compounds protected human cells against radiation-induced apoptosis exhibited low cytotoxicity. Compared to previous piperazine derivatives, compound 8 effect on cell survival in vitro toxicity vivo. It also enhanced mice 30 days after whole-body irradiation (although this increase was not statistically...
Primary cilia are dynamically regulated during cell cycle progression, specifically the G0/G1 phases of cycle, being resorbed prior to mitosis. can be visualized with highly sophisticated methods, including transmission electron microscopy, 3D imaging, or using software for automatic detection primary cilia. However, immunofluorescent staining is needed perform these methods. This publication describes a protocol easy in vitro by acetylated alpha tubulin (axoneme) and gamma (basal body)....
The increasing risk of acute large-scale exposure ionising irradiation on the population underlines necessity developing effective radioprotective and mitigating agents. aim this work was to investigate effect sodium orthovanadate pre-treatment mice exposed high doses gamma rays (from 5 13 Gy). determination median lethal dose within 30 days confirmed that applied total-body-irradiated intra-peritoneally has a but not effect. With pre-treatment, composition cellularity in bone marrow...
Early changes after radiation exposure may serve as predictors well targets for alleviation of radiation-induced injury in the lung.The aim our study was to examine alterations on cell and tissue levels lung blood immunological cytokines profiles induced by ionizing (IR) during first month irradiation mice experimental model.Female C57BL/6 were total body irradiated (TBI) 8 Gy.Lung samples collected 4, 24 h, 7, 21 30 d TBI.We measured absolute counts, populations profile evaluated...
Biodosimetry is focused on effects of ionizing radiation at cellular and molecular levels living organisms so that a qualified retrospective estimate load can be made. Two biodosimetry methods were evaluated in irradiated piglets: complete blood count analysis quantification chromosomal aberrations lymphocytes using micronucleus test. Animals whole-body with gamma doses 0-10 Gy. The was performed intervals ranging from 0 to 48 hours. Micronuclei measured 4 hours after irradiation. Changes...
Purpose: Among other reasons, the deteriorating global security situation and dangers associated with nuclear weapons have increased need for deeper knowledge of basic mechanisms involving human immune system ionizing radiation (IR).We conducted a review as to effects IR on thymic tissue, particularly development thymocytes T lymphocytes population in peripheral blood.Existing this topic is based part national registers that store records concerning irradiated people.The majority studies...
The kinetics of strontium, 85Sr, and cesium, 134Cs, were evaluated in a mouse experimental model to determine the impact these radionuclides on living organism concerning total body irradiation. Our study demonstrates that elimination rate 134Cs from skeleton teeth is influenced by irradiation presence 85Sr. Higher accumulation faster rates observed mice administrated with mixture + 85Sr radionuclides. Regarding only minimal effect was its skeleton, teeth, muscle mice. radionuclide mix more...
Primary cilia are dynamically regulated during cell cycle progression, specifically the G0/G1 phases of cycle, being resorbed prior to mitosis. can be visualized with highly sophisticated methods, including transmission electron microscopy, 3D imaging, or using software for automatic detection primary cilia. However, immunofluorescent staining is needed perform these methods. This publication describes a protocol easy in vitro by acetylated alpha tubulin (axoneme) and gamma (basal body)....