Anaplastic thyroid carcinoma is an undifferentiated aggressive tumor with a high rate of regional and distant spread grave prognosis (median survival, 3 months) no standardized treatment.To review the effect active treatment policy on outcome anaplastic carcinoma.Retrospective comparative study all patients diagnosed as having undergoing from January 1, 2008, through December 31, 2013, in tertiary university-affiliated medical center. Data were collected by record review. Final follow-up was...

Imaging is important for the diagnosis and follow-up of necrotizing external otitis (NEO). The best imaging modality controversy. To suggest 2-deoxy-2-[fluorine-18] fluoro-D-glucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) as an alternative to technetium-99m gallium-67 scans assessment response treatment patients with NEO.Case series.Tertiary referral center. From 2013 through 2017, 12 were diagnosed NEO based on clinical features positive FDG uptake within temporal...

Abstract Background Oral squamous cell carcinoma (OSCC) occurs in different subsites within the oral cavity. Our goal was to investigate epidemiological features of OSCC with relation age and subsite. Methods Retrospective review all patients treated for a tertiary care center between 2000 2018. Results A total 360 were included. Five groups defined: 0 30, 31 45, 46 60, 61 75, 76+. In 30 45 groups, 94.6% tumors originated tongue compared 87%, 66%, 61% 76+ respectively ( P < .001). higher...

Knowledge of the prevalence rates and associated risk markers vancomycin-resistant enterococci (VRE) colonization among long-term care facility (LTCF) residents could be used to improve screening policies newly admitted hospital inpatients. In a cross-sectional survey 1,215 LTCFs in Jerusalem, VRE carriage rate was 9.6%. Previous hospitalization antibiotic treatment were with elevated rate. contrast, moderate severe levels dependency prolonged stay, an LTCF decrease

Oral cavity squamous cell carcinoma may be more aggressive at presentation and recurrence in young patients compared with older patients. Dysregulation of microRNAs (miRNAs or miRs) has been associated the development prognosis oral cancer. The present study investigated miRNA expression tongue profiles were evaluated formalin‑fixed, paraffin‑embedded samples tumor normal mucosa from 12 aged <30 years old tongue. levels let-7f-5p, miR-30b-5p let-7e-5p upregulated tumors (P<0.05). let‑7f‑5p...

Hypothesis: Three-dimensional (3D)-printed microneedles can create precise holes on the scale of micrometers in human round window membrane (HRWM). Background: An intact is a barrier to delivery therapeutic and diagnostic agents into inner ear. Microperforation guinea pig has been shown overcome this by enhancing diffusion 35-fold. In humans, challenge design microneedle that precisely perforate thicker HRWM without damage. Methods: Based thickness mechanical properties HRWM, two designs...

To investigate the controversial relationship between preoperative calcium and parathyroid hormone levels dimensions histological features of adenoma in patients with primary hyperparathyroidism.Historical cohort.Tertiary medical centre.Clinical tumour-related data were collected from files all who underwent parathyroidectomy for hyperparathyroidism 1996-2012. Preoperative blood urine correlated size, weight volume adenoma. Pathohistological determined a representative sample archived...

Objectives/Hypothesis To present our 8‐year experience with transarterial embolization for head and neck bleeding, an emphasis on the need repeated procedures in patients treated cancer. Study Design Retrospective case series. Methods Tertiary university‐affiliated medical center. The cohort included 49 who underwent acute bleeding 2004 to 2012. Outcome measures procedural success, recurrence, complications, outcome. Results Mean patient age was 60.3 years. Indications were from a tumor...

Elective neck dissection for the clinically negative is often a matter of debate. A decision-analysis model that was published in 1994 established widely accepted principle warranted when risk occult metastases higher than 20%. The aim present study to build specific and up-to-date determine need elective during salvage laryngectomy after chemoradiation failure identify variables effect decision.Decision-analysis model.A performed compare outcome patients total with without an dissection....

There are only limited data in the literature, and none specifically from Middle East, on pathogenic bacteria chronic rhinosinusitis (CRS) as opposed to healthy nasal cavities their association with disease severity. The present study was conducted department of head neck surgery a tertiary medical center. meatal swabs were taken preoperatively patients CRS polyposis (CRSwNP) (n = 60), without (CRSsNP) 50), control septal deviation 26) or no abnormalities 27). Culture findings compared among...

Ultrasonography (US) is a reliable tool for the preoperative localization of parathyroid adenomas (PTAs). The aim this study was to evaluate accuracy US estimating both size and location PTAs effect operator expertise.Retrospective cohort study.A single tertiary medical center.All patients who underwent parathyroidectomy primary hyperparathyroidism between 1996 2012 were included. estimated PTA by ultrasound compared with intraoperative findings pathology report.The included 410 patients....

Malignant thymomas are among the least common mediastinal tumors in pediatric age group. Thymomas considered malignant on basis of macroscopic and microscopic invasiveness. As only 20 well-documented cases involving children have been reported literature, pattern responsiveness to therapy value prognostic signs is obscure. Two with pathognomonic histoimmunological features aggressive thymoma. One was cured, a follow-up 70 months, one died while therapy. Analysis histological immunoperoxidase...

Surveillance of postoperative vestibular schwannomas currently relies on manual segmentation and measurement the tumor by content experts, which is both labor intensive time consuming. We aimed to develop validate deep learning models for automatic gadolinium-enhanced T1-weighted magnetic resonance imaging (GdT1WI) noncontrast high-resolution T2-weighted (HRT2WI).A supervised machine approach using a U-Net model was applied segment images into pixels representing schwannoma background...