A5015859204- Fuel Cells and Related Materials
- Electrocatalysts for Energy Conversion
- Advancements in Solid Oxide Fuel Cells
- Supercapacitor Materials and Fabrication
- Advanced Nanomaterials in Catalysis
- Graphene research and applications
- Nanocluster Synthesis and Applications
- Carbon and Quantum Dots Applications
- Nerve injury and regeneration
- Pain Mechanisms and Treatments
- interferon and immune responses
- Neuroinflammation and Neurodegeneration Mechanisms
- Endoplasmic Reticulum Stress and Disease
- NF-κB Signaling Pathways
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Signaling Pathways in Disease
- Nuclear Receptors and Signaling
- RNA regulation and disease
- Histone Deacetylase Inhibitors Research
- Neurological Disorders and Treatments
- Diamond and Carbon-based Materials Research
- Advancements in Battery Materials
- Apelin-related biomedical research
- Ginseng Biological Effects and Applications
- Calcium signaling and nucleotide metabolism
Jining Medical University
2018-2024
Qingdao University
2018-2023
Taizhou People's Hospital
2023
Nantong University
2023
Taian City Central Hospital
2023
Hunan Institute of Mental Health
2021
Jiamusi University
2020
First Affiliated Hospital of Jiamusi University
2020
Huazhong University of Science and Technology
2014-2019
Wuhan University
2018
The aim of this study was to investigate whether uric acid (UA) might exert neuroprotection via activating the nuclear factor erythroid 2-related 2 (Nrf2) pathway and regulating neurotrophic factors in cerebral cortices after transient focal ischemia/reperfusion (FCI/R) rats. UA intravenously injected through tail vein (16 mg/kg) 30 min onset reperfusion rats subjected middle artery occlusion for h. Neurological deficit score performed analyze neurological function at 24 h reperfusion....
Objective: As a common chronic inflammatory skin disease, psoriasis seriously affects the physical health and psychological well-being of patients. Various clinical treatments for have their own drawbacks, so it is important to find effective safe drugs. Rehmannioside A (ReA) has anti-inflammatory properties main active ingredient in Fuzhengzhiyanghefuzhiyang decoction (FZHFZY), an herbal compound treatment psoriasis. But no studies been conducted determine whether ReA alone can treat...
MoOx quantum dots (QDs) were prepared using a one-step stirring treatment of molybdenum trioxide (MoO3) powder in dimethyl sulfoxide (DMSO). Besides their highly sensitive label-free metal ion and pyrophosphate sensing, the antibacterial activity as-prepared QDs was discovered for first time.
Hybrid carbon films composed of graphene film and porous may give full play to the advantages both materials, have great potential for application in energy storage conversion devices. Unfortunately, there are very few reports on fabrication hybrid films. Here we demonstrate a simple approach fabricate free-standing sandwich-structured amorphous multilayer by chemical vapor deposition controllable scalable way. reveal good electrical conductivity, excellent flexibility, compatibility with...
Liquiritin, a key component extracted from Glycyrrhiza radix, exhibits variety of physiological effects. This study investigates the role liquiritin in progression breast cancer. investigation conducted experiments using two cancer cell lines treated with varying concentrations liquiritin, further validating our findings vivo. Bioinformatics analysis was used to identify pathways potentially regulated by The results indicated that epidermal growth factor receptor (EGFR) and mitogen-activated...
Abstract Vanadium oxide (VO x ) nanomaterials have been attracting great attention recently due to their outstanding physicochemical properties. Engineering VO into quantum dots (QDs) should bring new properties and potential for applications, but has not reported until now. Meanwhile, the shortcomings in QDs synthesis such as needing high temperature expensive instruments still need be overcome. Herein, were generated via a simple ultrasonic agitation strategy at room using DMSO both...
Effect of CXCL8 gene silencing‑mediated JAK‑STAT signaling pathway on epithelial‑mesenchymal transition (EMT) human cutaneous melanoma cells was explored. Eighty patients with were enrolled in the study. Cells transfected accordingly and divided into five groups: The blank group (human cells), NC + vector plasmid transfection), siRNA silent expression AG490 signal inhibitor transfection). levels CXCL8, JAK2, STAT3, epithelial cadherin (E‑cadherin), neurotrophic (N‑cadherin) vimentin tissues...
The clinical use of doxorubicin (DOX) is limited by its cardiotoxicity, which closely associated with oxidative stress. Xinmailong (XML) a bioactive peptide extracted from American cockroaches, has been mainly applied to treat chronic heart failure in China. Our previous study showed that XML attenuates DOX‐induced However, the mechanism cardiotoxicity remains unclear. Heme oxygenase‐1 (HO‐1), an enzyme ubiquitously expressed all cell types, found take antioxidant effects many cardiovascular...
A new and simple approach is proposed for the first time to fabricate free-standing amorphous carbon films (FS-ACFs) with controllable thickness by ambient pressure chemical vapor deposition (APCVD). The uses methane as source Ni foil catalytic substrate, in which a large number of atoms are trapped controlling experimental conditions during APCVD growth process, FS-ACFs obtained corrosion after growth. having uniform continuous morphology variable sizes over one hundred square centimeters...
The effect of histone deacetylase (HDAC)2/Inositol polyphosphate‑5‑phosphatase F (Inpp5f) on neuropathic pain and cognitive dysfunction through regulating PI3K/Akt/GSK‑3β signal pathway in rats with was investigated. A total 80 SPF mature male SD were averagely randomized into the sham operation group, model HDAC2 intervention group (group A) Inpp5f B). rat models established groups B. At 15th day after modeling, transfected interference vector HDAC2, B overexpression Inpp5f. Rats four...
S100 calcium-binding protein A16 (S100A16) has previously been reported to play a role in tumor cells. Nevertheless, the that S100A16 played nephroblastoma cells remains obscure. The expression of and DEPDC1 were detected via RT-q PCR western blotting. Cell transfection was performed overexpress or interfere S100A16. CCK8 applied for assessment cell viability. apoptotic level capabilities WiT49 proliferate, invade migrated appraised utilizing Tunel, colony formation Transwell, wound healing,...
Silver-based ceramic composite electrodes are expected to be widely applied in mediumor lowtemperature solid oxide fuel cells (SOFCs), SOFCs operated on carbon-containing fuels, and electrolysis (SOECs). To optimize the composition of a silver-based electrode, performances Ag-YSZ (yttrium-stabilized zirconia) Ag-GDC (gadolinium doped ceria) investigated. First, they used as electrode materials make symmetric YSZ electrolyte, which impedance spectra measured an ambient atmosphere evaluate...
The aim of this study was to elucidate the neuronal protection effect sodium butyrate (NaB) on apoptosis in rats with cerebral infarction (CI), and involvement phosphatidilinositol 3-kinase/protein kinase B (PI3K/Akt) extracellular-signal-regulated 1/2 (ERK1/2) pathways. MI model performed by middle artery occlusion (MCAO). Three hours after reperfusion, gastric administration 5 or 10 mg/kg NaB performed. Neurological deficit score, infarct size brain edema were evaluated 24 h reperfusion....
Hdac2/Inpp5f on the therapeutic effect of pregabalin neuropathic pain in chronic constriction injury (CCI) rats was investigated. A total 90 healthy SD were selected and divided into treatment group, model control group normal with 30 each group. Rats groups used to construct CCI model. The treated sham surgery. not after 8th day operation. Behavioral experiments performed measure mechanical withdrawal threshold (MWT) thermal latency (TWL). expression inflammatory cytokines TNFα IL-1β...