A5102856718- interferon and immune responses
- Cancer-related molecular mechanisms research
- Animal Nutrition and Physiology
- Polysaccharides and Plant Cell Walls
- Studies on Chitinases and Chitosanases
- Cytomegalovirus and herpesvirus research
- RNA regulation and disease
- Phytase and its Applications
- Genomics and Chromatin Dynamics
- Viral Infections and Immunology Research
- Kruppel-like factors research
- Immune Response and Inflammation
- Viral Infectious Diseases and Gene Expression in Insects
- Animal Disease Management and Epidemiology
- Epigenetics and DNA Methylation
- Transgenic Plants and Applications
- Immune Cell Function and Interaction
- Protein purification and stability
Southwest University
2012-2025
Chongqing University
2021
Porcine transmissible gastroenteritis virus (TGEV) is a highly contagious pathogen causing severe diarrhea in pigs, particularly piglets, leading to significant economic losses. Distinguishing TGEV from the genetically similar porcine respiratory coronavirus (PRCV) remains challenging due their high genomic homology. In this study, we developed one-pot assay combining recombinase-aided amplification (RAA) and CRISPR/Cas13a technology, targeting S gene. This method was optimized for...
This study was conducted to evaluate the adjuvant potential of sulfated Radix Cyathulae officinalis Kuan polysaccharides (sRCPS) and their effects on specific cellular humoral immune responses hepatitis B subunit vaccine in mice. Our data demonstrated that sRCPS significantly promoted rHBsAg-specific IgG, IgG1, IgG2a, IgG2b antibody titers, activities natural killer cells (NK) cytotoxic T lymphocytes (CTL), proliferation, phagocytic capacity peritoneal macrophages. Furthermore, increased...
Swine hepatitis E (swine HE) is a new type of zoonotic infectious disease caused by the swine virus HEV). Open reading frame 3 (ORF3) an important virulent protein HEV, but its function still mainly unclear. In this study, we generated adenoviruses ADV4-ORF3 and ADV4 negative control (ADV4-NC), which successfully mediated overexpression enhanced green fluorescent (EGFP)-ORF3 EGFP, respectively, in HepG2 cells. High-throughput sequencing was used to screen for differentially expressed long...
Breast cancer (BC) ranks first among malignancies in the female population due to its complicated pathological progression and poor prognosis. Hence, aim of present study was identify potential molecular prognostic biomarkers able predict prognosis BC patients. We integrated two microRNA (miRNA) expression microarrays three gene related from NCBI Gene Expression Comprehensive (GEO) database screen for differentially expressed miRNAs their regulatory networks. The Kaplan-Meier plotter online...
Interferen-γ of Rongchang porcine was amplifed by RT-PCR with the total RNA extracted from peripheral blood lymphocytes. The gene sequenced after cloned into vector pMD18-T and analyzed molecular biological software. results showed that opening reading frame (ORF) interferen-γ consists 501 nucleotides, encoding 166 amino acids, front 23 acide is signal peptide. homology IFN-γ rongchang chenghua interferon 99.8% at nucleotide level. susscrofa 96.8%. camel, rabbit, horse, goat, cattle, gorilla...
Effect of carboxymethyl chito-oligosaccharide on cysteine absorption in intestinal porcine epithelial cells | Huayu Huang, Chen Zhang, Luqiu Feng, Naixiu Wang, Kai Zhenhui Song, Ling Gan Agricultural Journals