A5059169025- Reproductive System and Pregnancy
- Research on Leishmaniasis Studies
- Ovarian function and disorders
- Toxin Mechanisms and Immunotoxins
- Immunotherapy and Immune Responses
- Escherichia coli research studies
- Reproductive Biology and Fertility
- Antibiotic Resistance in Bacteria
- Endometriosis Research and Treatment
- Birth, Development, and Health
- RNA Interference and Gene Delivery
- vaccines and immunoinformatics approaches
- Monoclonal and Polyclonal Antibodies Research
- Immune Cell Function and Interaction
- Pharmacological Effects of Natural Compounds
- Phytoestrogen effects and research
- Immune Response and Inflammation
- Hepatitis B Virus Studies
- Pesticide Exposure and Toxicity
- Mesenchymal stem cell research
- Ovarian cancer diagnosis and treatment
- Menopause: Health Impacts and Treatments
- Tissue Engineering and Regenerative Medicine
- Pain Mechanisms and Treatments
- Insect Pest Control Strategies
Shahid Beheshti University of Medical Sciences
2015-2024
Denver School of Nursing
2022
Triangle
2022
Indianapolis Zoo
2022
Gainesville Obstetrics & Gynecology
2022
Committee on Publication Ethics
2022
Shahid Beheshti University
2003-2019
Tehran University of Medical Sciences
2009-2018
Islamic Azad University, East Tehran Branch
2015
Islamic Azad University South Tehran Branch
2015
Background: Amphotericin B (Amp) and Betulinic acid (BA) as antileishmanial agents have negligible water solubility high toxicity. To solve these problems, for the first time, chitosan nanoparticles Anionic Linear Globular Dendrimer (D) were synthesized treatment of Leishmania major ( L. major) . Method: Chitosan dendrimer synthesized, Amp BA loaded into nanoparticles. The particles then characterized using various methods their efficacy was evaluated in vitro vivo environments (parasite...
Regarding the antiparasitic effects of Betulinic acid (B) against Leishmaniasis, it was loaded into nanochitosan (K) for first time in order to improve its therapeutic and decrease side treatment Leishmania major-infected Balb/c mice. Improvement efficacy Bas an anti-leishmania agent through increasing effective dose achieved by using a novel solvent phase separation method K synthesis. The synthesized with size 102 nm acid-nanochitosan (BK) 124 drug loading efficiency 93%, cellular uptake...
Improvement in the treatment of Leishmania major's pathological effects through increasing dose amphotericin B loaded into nanochitosan.The phase separation method was used for nanochitosan synthesis and loading. Also a novel solvent designed nanodrug efficacy evaluated vitro vivo (pathology) environments.The drug loading efficiency 90%, along with slow drug-release cellular uptake 98.6% achieved. The composed 10% acetic acid, it succeeded to dissolve AK10 mg/kg. Also, mg/kg had no side...
This study investigates the therapeutic effect of vitamin C on development endometrial lesions and fecundity disorders in ovarian induction model mouse endometriosis.Ovarian endometriosis was surgically induced 14 NMRI female mice (treatment group, N = 7) (control 7). Three days after second surgery (to assess endometriotic implant), were randomized into two intervention groups: control (placebo) treatment (50 mg/kg every orally for four weeks) groups. In oestrus phase, sacrificed....
Evidence indicates that neuropathic pain pathogenesis is not confined to changes in the activity of neuronal systems but involves interactions between neurons, inflammatory immune and immune-like glial cells. Substances released from cells during inflammation play an important role development maintenance pain. It has been found minocycline suppresses Here, we evaluated analgesic effect a chronic constriction injury (CCI) model rat assessed IL-6 concentration cultured macrophage microglia...
Toll-like receptors (TLR) are one of the major compartments innate immune system. It was revealed that TLR have relevance in ovulation, sperm capacitation and fertilisation. So, this study, expression TLR, their adaptor molecules cytokines human fallopian tube cell line under effect normal spermatozoa evaluated. mRNA protein were evaluated OE-E6/E7 line. Semen samples from 10 donors collected co-incubated with used as group, without control group. Afterwards, level molecule cytokine compared...
Induction of protein synthesis by the external delivery
Because of the importance pre-eclampsia and proteinuria in pregnancy, a faster simpler diagnostic method is needed.To compare random urine protein to creatinine ratio (p:c ratio) with 24-h excretion rate pregnant women suspicion pre-eclampsia.The study was conducted on 100 gestational ages >or=20 weeks; 50 patients were suspected having healthy women. A sample for p:c determination measurement obtained.All had significant proteinuria. The single-voided demonstrated sensitivity 94%...
The aerial parts of Tanacetum balsamita subsp. were collected at full flowering stage from Tabriz, Iran. essential oil was isolated by hydrodistillation and analyzed combination capillary GC GC-MS. Twenty seven components identified, representing 99.2% the total oil. Carvone (51.0%), beta-thujone (20.8%), 1,8-cineole (4.4%) alpha-thujone (3.2%) main components. in vitro antimicrobial activity T. studied against eight Gram-positive Gram-negative bacteria (Bacillus subtilis, B. pumulis,...