A5056781533- Eating Disorders and Behaviors
- Obsessive-Compulsive Spectrum Disorders
- Impact of Technology on Adolescents
- Pancreatitis Pathology and Treatment
- Radiation Dose and Imaging
- Obesity, Physical Activity, Diet
- Behavioral Health and Interventions
- Digital Mental Health Interventions
- Cardiac, Anesthesia and Surgical Outcomes
- Pancreatic and Hepatic Oncology Research
- Global Maternal and Child Health
- Autism Spectrum Disorder Research
- Appendicitis Diagnosis and Management
- Intestinal and Peritoneal Adhesions
- Traumatic Brain Injury and Neurovascular Disturbances
- Child Nutrition and Feeding Issues
- Maternal and Perinatal Health Interventions
- Patient-Provider Communication in Healthcare
- Hernia repair and management
- Mobile Health and mHealth Applications
- Pediatric Pain Management Techniques
- Radiology practices and education
- Body Image and Dysmorphia Studies
- Psoriasis: Treatment and Pathogenesis
- Kidney Stones and Urolithiasis Treatments
National Institutes of Health
2023
St Ann’s Hospital
2009-2020
George Washington University
2016-2019
Clatterbridge Cancer Centre NHS Foundation Trust
2015-2018
George Washington University Hospital
2017
St Ann's Hospital
2014-2016
Washington University Medical Center
2016
Barnet Enfield and Haringey Mental Health Trust
2014-2016
Dorset HealthCare University NHS Foundation Trust
2015
Texas A&M Health Science Center
2014
Anorexia nervosa (AN) in adults has poor outcomes, and treatment evidence is limited. This study evaluated the efficacy acceptability of a novel, targeted psychological therapy for AN (Maudsley Model Nervosa Treatment Adults; MANTRA) compared with Specialist Supportive Clinical Management (SSCM).One hundred forty-two outpatients broadly defined (body mass index [BMI] ≤ 18.5 kg/m²) were randomly allocated to receive 20 30 weekly sessions (depending on clinical severity) plus add-ons (4...
Generalized pustular psoriasis (GPP) is a severe, potentially life-threatening inflammatory dermatosis, which traditionally difficult to manage. Recent evidence suggests that interleukin (IL)-1 plays central role in the disease pathogenesis, and thus makes use of IL-1 inhibitors effective. Two patients with recalcitrant GPP were enrolled an open-label, expanded access study receive new IL-1β inhibitor, gevokizumab. The two had respective 79% 65% reduction area severity index scores at weeks...
Anorexia nervosa (AN) is a biologically based serious mental disorder with high levels of mortality and disability, physical psychological morbidity impaired quality life. AN one the leading causes disease burden in terms years life lost through death or disability young women. Psychotherapeutic interventions are treatment choice for AN, but results psychotherapy depend critically on stage illness. The response adults chronic form illness poor drop-out from high. Despite seriousness...
Risk-appropriate prenatal care has been asserted as a way for the cost-effective delivery of care. A virtual model potential to provide patient-tailored, risk-appropriate educational content and may facilitate vital sign weight monitoring between visits. Previous studies have demonstrated safe reduction in frequency in-person visits among low-risk patients but noted patient satisfaction.
Objective This study reports follow-up data from a multicenter randomized controlled trial (n = 142) comparing the Maudsley Model of Anorexia Nervosa Treatment for Adults (MANTRA) with Specialist Supportive Clinical Management (SSCM) in outpatients broadly defined anorexia nervosa (AN). At 12 months postrandomization, all patients had statistically significant improvements body mass index (BMI), eating disorder (ED) symptomatology and other outcomes no differences between groups. MANTRA was...
ABSTRACT Objective This study aimed to explore the neuro‐ and social‐cognitive profile of a consecutive series adult outpatients with anorexia nervosa (AN) when compared widely available age gender matched historical control data. The relationship between performance profiles, clinical characteristics, service utilization, treatment adherence was also investigated. Method Consecutively recruited broad diagnosis AN (restricting subtype AN‐R: n = 44, binge‐purge AN‐BP: 33 or Eating Disorder...
Abstract Objectives Forming part of a process evaluation large randomised controlled trial (the Maudsley Outpatient Study Treatments for Anorexia Nervosa and Related conditions, MOSAIC) comparing two outpatient therapies (AN), the Model Treatment Adults with (MANTRA) Specialist Supportive Clinical Management (SSCM), this study adopted qualitative approach to examine therapist experiences treatment delivery. Method Twenty MOSAIC therapists completed semi‐structured interviews. Interviews were...
ABSTRACT Objective Case formulation is a core component of many psychotherapies and letters may provide an opportunity to enhance the therapeutic alliance improve treatment outcomes. This study aimed determine if predict satisfaction, session attendance, symptom reductions in anorexia nervosa (AN). It was hypothesized that higher quality would greater number attended sessions, improvement eating disorder symptoms. Method Patients were adult outpatients with AN ( n = 46) who received Maudsley...
This study is part of a series process evaluations within the MOSAIC Trial (Maudsley Outpatient Study Treatments for Anorexia Nervosa and Related Conditions). randomised controlled trial (RCT) compared two psychological treatments, Maudsley Model Treatment Adults with (MANTRA) Specialist Supportive Clinical Management (SSCM) adult outpatients Nervosa. The present integrates quantitative (treatment acceptability credibility) qualitative (written) feedback to evaluate patients' treatment...
Despite their use in clinical practice, there is little evidence to support the of therapist written goodbye letters as therapeutic tools. However, preliminary suggests that may have benefits treatment anorexia nervosa (AN).This study aimed examine whether were associated with improvements body mass index (BMI) and eating disorder symptomology patients AN after treatment.Participants adults (n = 41) who received The Maudsley Model Anorexia Treatment for Adults (MANTRA) a trial evaluating two...
Abstract Cultural issues appear to play an important role in the eating problems of adolescents. Asian adolescent girls living U.K. have unusually high levels psychopathology, with a particular emphasis on bulimic behaviours and attitudes. This study examines these cultural differences patterns more detail among group schoolgirls A complex pattern attitudes emerged. were likely fast, but Caucasian binged often than Asians. Possible explanations for two psychopathology are considered,...
Abstract Background Rectal microbicides (RM) are biomedical HIV prevention products that aim to prevent or reduce the transmission of and other sexually transmitted infections (STIs). RM modalities may be beneficial for populations who have complex lifestyles, difficulties adhering pre-exposure prophylaxis (PrEP) regimens, and/or limited access care. MTN-035 (DESIRE; Developing Evaluating Short-Acting Innovations Use), a randomized crossover trial, aimed evaluate safety acceptability of,...