A5058849265- Mental Health and Psychiatry
- Psychosomatic Disorders and Their Treatments
- Body Image and Dysmorphia Studies
- Hallucinations in medical conditions
- Colorectal Cancer Treatments and Studies
- Cancer Immunotherapy and Biomarkers
- Acute Myeloid Leukemia Research
- Immune cells in cancer
- Cytokine Signaling Pathways and Interactions
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Simulation-Based Education in Healthcare
- Schizophrenia research and treatment
- Melanoma and MAPK Pathways
University of Canterbury
2015-2020
For patients with advanced non-small-cell lung cancer (NSCLC), dual immune checkpoint blockade (ICB) CTLA4 inhibitors and PD-1 or PD-L1 (hereafter, PD-(L)1 inhibitors) is associated higher rates of anti-tumour activity immune-related toxicities, when compared treatment alone. However, there are currently no validated biomarkers to identify which will benefit from ICB1,2. Here we show that NSCLC who have mutations in the STK11 and/or KEAP1 tumour suppressor genes derived clinical ICB...
Dissociative identity disorder (DID) and schizophrenia-spectrum disorders (SSD) share some overlapping phenomenological features making accurate diagnosis more difficult. Childhood abuse depersonalization have been associated with psychotic symptoms across psychological but their relationship to phenomenology remains understudied.The present study used quantitative measures examine (1) similarities differences in voice hearing experiences, interpretations of voices, thought individuals DID...
Previous research has shown that the relationship between childhood abuse and presence of auditory hallucinations is mediated by dissociation, specifically depersonalization absorption. The current study assessed dissociation as a mediator hallucination frequency, characteristics associated distress in those with dissociative identity disorder (DID; n = 50) schizophrenia spectrum disorders (SSD; 49). It also tested whether non-auditory hallucinations. Participants completed measures abuse,...
Simulation practices are growing in both popularity and necessity within speech pathology programs. use can serve to not only minimize client risk but increase student confidence competence prior patient contact, particularly with low incidence or medically fragile patients. This paper describes reflects on four individual simulation experiences one graduate language program their outcomes. The of simulated patients mannequin training resulted an students' perception knowledge clinical skills medical
<h3>Background</h3> The tumor microenvironment (TME) contains immunosuppressive myeloid cells that contribute to checkpoint inhibitor (CPI) resistance. One approach as part of Pionyr Immunotherapeutics' Myeloid Tuning™ strategy is reprogram acquire an immunostimulatory anti-tumor phenotype. Macrophage Receptor with a Collagenous Structure (MARCO) attractive target for reprogramming, considering its immunomodulatory function and expression on tumor-associated macrophages (TAMs) monocytic...