A5047624164- RNA modifications and cancer
- Innovation and Knowledge Management
- Quality and Supply Management
- Lung Cancer Treatments and Mutations
- ICT Impact and Policies
- Sustainable Supply Chain Management
- Cancer-related gene regulation
- Plasma Applications and Diagnostics
- Epigenetics and DNA Methylation
- Environmental Sustainability in Business
- Advanced Fluorescence Microscopy Techniques
- Outsourcing and Supply Chain Management
- Advanced Sensor and Energy Harvesting Materials
- Quality and Management Systems
- 3D Printing in Biomedical Research
- Surgical Sutures and Adhesives
- Customer Service Quality and Loyalty
- E-Government and Public Services
- Supply Chain and Inventory Management
- Construction Project Management and Performance
- Catalytic Processes in Materials Science
- Cutaneous lymphoproliferative disorders research
- Innovation Diffusion and Forecasting
- Genomics and Chromatin Dynamics
- Photonic and Optical Devices
Commercial Aircraft Corporation of China (China)
2025
Fudan University
2024
Massachusetts Institute of Technology
2017-2024
University of Idaho
2022-2024
Brigham and Women's Hospital
2020-2024
Harvard University
2018-2024
Henan University
2024
Fordham University
2011-2023
Moffitt Cancer Center
2019-2022
Molecular Oncology (United States)
2019-2022
Abstract The efficacy of antiretroviral therapy is significantly compromised by medication non-adherence. Long-acting enteral systems that can ease the burden daily adherence have not yet been developed. Here we describe an oral dosage form composed distinct drug–polymer matrices which achieved week-long systemic drug levels antiretrovirals dolutegravir, rilpivirine and cabotegravir in a pig. Simulations viral dynamics patient patterns indicate such would reduce therapeutic failures...
For decades, bioadhesive materials have garnered great attention due to their potential replace sutures and staples for sealing tissues during minimally invasive surgical procedures. However, the complexities of delivering bioadhesives through narrow spaces achieving strong adhesion in fluid-rich physiological environments continue present substantial limitations translation existing sealants. In this work, a new strategy tissue based on multilayer patch, which is designed repel body fluids,...
Abstract Tissue adhesives are promising alternatives to sutures and staples for joining tissues, sealing defects, immobilizing devices. However, existing mostly take the forms of glues or hydrogels, which offer limited versatility. We report a direct-ink-write 3D printable tissue adhesive can be used fabricate bioadhesive patches devices with programmable architectures, unlocking new potential application-specific designs. The is conformable stretchable, achieves robust adhesion wet tissues...
ABSTRACT We develop a theoretical definition of operational capabilities, based on the strategic management and operations literature, differentiate this construct from related constructs resources practices, drawing upon resource‐based view firm as our foundation. illustrate key features capabilities using illustration restaurant kitchen. Because traits are distinct, they create barrier to imitation, making them potential source competitive advantage. However, particularly challenging...
Purpose This study aims to investigate how firms should customize quality practices obtain or maintain advantage with the development of culture. The paper seeks adopt March's learning framework and differentiate management into two bundles: exploitation exploration. Design/methodology/approach A survey dataset, including 238 manufacturing plants located in eight countries three industries was used test hypotheses. total sample classified groups depending on maturity culture, regression...
Lung adenocarcinoma is a major form of lung cancer, which the leading cause cancer death. Histone methylation reader proteins mediate effect histone methylation, hallmark epigenetic and transcriptional regulation gene expression. However, their roles in are poorly understood. Here, our bioinformatic screening analysis search adenocarcinoma-promoting protein show that heterochromatin 1γ (HP1γ; also called CBX3) among most frequently overexpressed amplified human adenocarcinoma, high HP1γ mRNA...
Purpose Operational practices and operational capabilities are critical yet distinct elements in operations strategy. The purpose of this paper is to examine their conceptual differences explore how they developed a portfolio, considering the potential for be either compensatory or additive nature. Design/methodology/approach model argues that lack investments certain can offset by higher level other capabilities. In contrast, firm must invest trade‐offs impossible. authors evidence these...
Purpose – One of the commonly cited problems in implementation quality practices is related to cultural resistance change. While importance organizational culture management (QM) has been recognized recent literature, little known about how influences performance. The purpose this paper examine mechanism nurture a firm Design/methodology/approach This study empirically assesses path from infrastructure practices, core and finally performance using data collected 397 Chinese manufacturing...
The purpose of this paper is twofold. first objective to examine the core resources that make environmental management system (EMS) a potential basis sustainable competitive advantage from resource-based view firm. second investigate set contingency perspective. Particularly, experience in implementing other manufacturing systems and stage EMS implementation were tested as factors. proposed model its related hypotheses using structural equation modeling on large-scale database consisting...
The novel uncoupling proteins (UCP2-5) are implicated in the mitochondrial control of oxidant production, insulin signaling, and aging. Attempts to understand their functions have been complicated by overlapping expression patterns most organisms. Caenorhabditis elegans nematodes unique because they express only one UCP ortholog, ceUCP4 (ucp4). Here, we performed detailed metabolic analyzes genetically modified define function ceUCP4. knock-out mutant ucp4 (ok195) exhibited sharply decreased...
In order to verify the airworthiness of handling quality after control surface malfunction MOC8 test in civil aircraft, a detailed analysis is conducted on clause CCAR25.671(c). The fidelity requirement engineering simulator for examined, and proposed method evaluating presented. Additionally, explanation provided evaluation grade. A verification scheme process are designed conducting test. Finally, an example involving loss elevator pitch used demonstrate that these research findings have...
The inclusion of modification items and test equipment on the aircraft renders it unattainable to achieve minimum weight as defined by design during flight test. Consequently, is imperative conduct MOC8 engineering simulator. This paper presents a comprehensive analysis airworthiness clause pertaining weight, devises scenario for verifying compliance with requirements, proposes methodology conducting conformity verification based weight. research findings have been successfully applied in...
This study investigates the multiplex association between gender inequality and healthcare. The aim of is to comprehend how inequalities in affect healthcare across different populations worldwide. Visualization was conducted effect various variables on indicators. emphasizes critical need for eliminating reduce disparities By analyzing publicly available data from World Bank, we find that higher access anti-retroviral drugs associated with a lower incidence human immunodeficiency virus...