P. I. Kobo

ORCID: 0000-0003-1776-6144
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About
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Research Areas
  • Trypanosoma species research and implications
  • Research on Leishmaniasis Studies
  • Pharmacological Effects and Toxicity Studies
  • Neuroscience and Neuropharmacology Research
  • Epilepsy research and treatment
  • Ginger and Zingiberaceae research
  • Vitamin C and Antioxidants Research
  • Phytochemistry and biological activities of Ficus species
  • Marriage and Sexual Relationships
  • Biochemical and Molecular Research
  • Ethnobotanical and Medicinal Plants Studies
  • Calcium signaling and nucleotide metabolism
  • Essential Oils and Antimicrobial Activity
  • African Botany and Ecology Studies
  • Bioactive Compounds and Antitumor Agents
  • Synthesis and Biological Evaluation

Ahmadu Bello University
2013-2024

Aim:The study was carried out to determine the in vivo antitrypanosomal effect of methanolic extract Zingiber officinale (ginger) Trypanosoma brucei brucei-infected mice.Materials and Methods: Twenty-five mice were randomly allocated into five groups animals each.Group I II given Tween 80 (1 ml/kg) diminazene aceturate (3.5 mg/kg) serve as untreated treated controls, respectively.Groups III-V received at 200, 400 800 mg/kg body weight, respectively.All treatments for 6 consecutive days...

10.14202/vetworld.2014.770-775 article EN cc-by Veterinary World 2014-10-01

The aim of this study was to investigate the ameliorative effect Lawsonia inermis Linn used traditionally against trypanosomosis. Twenty-five adult Wistar rats both sex were individually infected intraperitoneally (IP) with 106 Trypanosoma congolense per ml blood. Following establishment infection, randomly divided into five groups 5 each. Rats in I, II, and III treated 125, 250 500 mg/kg extract, respectively, while IV V 3.5 2 ml/kg diminazene aceturate (DM) once physiological buffered...

10.1016/j.ijvsm.2016.10.005 article EN cc-by-nc-nd International Journal of Veterinary Science and Medicine 2016-12-01

The effect of Daflon® 500 mg (DF) and Diminazene aceturate (DZ) on the lipid profile adult male Wistar rats infected with T. brucei were investigated for their use in trypanosomosis. Fifty randomly divided into 5 groups 10 each. Group I treated distilled water (1 mL/kg) per os, while group II 6 intraperitoneally (10 trypanosomes/mL blood). III blood) administered DZ at 3.5 mg/kg once, when infection was established. Groups IV Vwere first pretreated DF 100 os three weeks, followed by...

10.51791/njap.v50i2.3968 article FR Nigerian Journal of Animal Production 2024-02-28
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