- Antibiotic Resistance in Bacteria
- Antibiotics Pharmacokinetics and Efficacy
- Pharmaceutical and Antibiotic Environmental Impacts
- Toxoplasma gondii Research Studies
- Pesticide Residue Analysis and Safety
- Animal Ecology and Behavior Studies
- Pharmacological Effects and Assays
- Bird parasitology and diseases
- Insect and Pesticide Research
- Essential Oils and Antimicrobial Activity
- Vector-borne infectious diseases
- Garlic and Onion Studies
- African Botany and Ecology Studies
- Ethnobotanical and Medicinal Plants Studies
- Escherichia coli research studies
- Salmonella and Campylobacter epidemiology
- Occupational Health and Performance
- Sports injuries and prevention
- Shoulder Injury and Treatment
- Antimicrobial Peptides and Activities
- Salivary Gland Disorders and Functions
Al-Azhar University
2024
University of Pretoria
2010-2023
Onderstepoort Veterinary Academic Hospital
2018-2023
Ahmadu Bello University
2014
Antimicrobial resistance (AMR) and recently mobilized colistin (mcr-1) associated among Escherichia coli isolates have been attributed to the overuse of antimicrobials in livestock production. E. remains an important pathogen, often with mortality low carcass weight poultry medicine; therefore, need use is common. The study aimed determine AMR profile presence mcr-1 mcr-2 genes avian pathogenic from samples tested at a bacteriology laboratory for routine diagnosis. This first step...
Diclofenac caused the death of millions vultures on Asian subcontinent. Other non-steroidal anti-inflammatory drugs (NSAIDs) have since also been shown to be toxic with exception meloxicam. For this study, we evaluated effect diclofenac renal uric acid transport and glomerulus filtration in an acute toxicity model. In a two-phase study same birds, healthy chickens (a validated model species) were treated intravenously para-amino hippuric (PAH) iohexol (IOH) combination phase 1. 2, PAH IOH...
Diclofenac was responsible for the decimation of Gyps vulture species on Indian subcontinent during 1980s and 1990s. vultures are extremely sensitive (the lethal dose 50 [LD50] ~ 0.1 mg/kg – 0.2 mg/kg), with toxicity appearing to be linked metabolic deficiency, demonstrated by long T1/2 (~12 h 17 h). This is in striking comparison domestic chicken (Gallus gallus domesticus), which LD50 ~10 ~1 h. The phase 1 cytochrome P450 (CYP) 2C subfamily has been cited as a possible reason deficiency....
Abstract Background Antimicrobial resistance (AMR) is a global health problem largely due to the overuse of antimicrobials. In recognition this, World Health Assembly in 2015 agreed on action plan tackle AMR. Following emergence mcr‐1 ‐associated colistin gene livestock industry 2016, several countries including South Africa restricted veterinary use as threatens clinical utility drug. This study follow‐up restriction place order evaluate impact such policy adoption. Objective To assess...
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Lipid oxidation and microorganism growth cause a reduction in cupcake qualities. Because of the harmful effects synthetic preservatives, there is growing demand for preservatives natural antioxidants. In this study, phytochemical properties antimicrobial activity Emblica oficinalis (amla) were investigated. Then effect adding amla extract at levels 1, 2, 3% on qualitative attributes cupcakes was examined. produced samples, antioxidant compared by assessing DPPH%, peroxide values, free fatty...
Colistin and carbapenems are critically important antimicrobials often used as a last resort to manage multidrug-resistant bacterial infections in humans. With limited alternatives, resistance these is of concern organisms could potentially spread horizontally rendering treatments ineffective. The aim this study was investigate co-resistance colistin among Escherichia coli isolated from poultry South Africa. Forty-six E. strains obtained clinical cases breeder broiler chickens were used. In...