Aptamers that undergo conformational changes upon small-molecule recognition have been shown to gate the ionic flux through nanopores by rearranging charge density within aptamer-occluded orifice. However, mechanistic insight into such systems where biomolecular interactions are confined in nanoscale spaces is limited. To understand fundamental mechanisms facilitate detection of analytes inside structure-switching aptamer-modified nanopores, we correlated experimental observations...

Nitrate (NO3-) contamination is becoming a major concern due to the negative effects of an excessive NO3- presence in water which can have detrimental on human health. Sensitive, real-time, low-cost, and portable measurement systems able detect extremely low concentrations are thus important. In this work, we present novel method realize low-cost easy fabricate amperometric sensor capable detecting small real samples. The fabrication technique combines printing silver (Ag) working electrode...

Abstract In the food industry, innovative packaging solutions are increasingly important for reducing waste and contributing to global sustainability efforts. However, current is generally passive unable adapt changes in environment real time. To address this, a battery‐less autonomous smart system developed that wirelessly powers closed‐loop sensing release of active compounds. This integrates gas sensor real‐time monitoring, Near‐Field Communication (NFC) antenna, controlled compounds...

Heterocyclic amine histamine is a well-known foodborne toxicant (mostly linked to "scombroid poisoning") synthesized from the microbial decarboxylation of amino acid histidine. In this work, we report fabrication flexible screen-printed immunosensor based on silver electrode coated with single-walled carbon nanotubes (SWCNTs) for detection directly in fish samples. Biosensors were realized by first spray depositing SWCNTs working electrodes and subsequently treating them oxygen plasma reduce...

Aptamers are chemically synthesized single-stranded DNA or RNA oligonucleotides widely used nowadays in sensors and nanoscale devices as highly sensitive biorecognition elements. With proper design, aptamers able to bind a specific target molecule with high selectivity. To date, the systematic evolution of ligands by exponential enrichment (SELEX) process is employed isolate aptamers. Nevertheless, this method requires complex time-consuming procedures. In silico methods comprising machine...

In this work, we propose a novel disposable flexible and screen-printed electrochemical aptamer-based sensor (aptasensor) for the rapid detection of chlorpyrifos (CPF). To optimize process, various characterization procedures were employed, including Fourier transform infrared spectroscopy (FT-IR), impedance (EIS), cyclic voltammetry (CV). Initially, aptasensor was optimized in terms electrolyte pH, aptamer concentration, incubation time chlorpyrifos. Under optimal conditions, showed wide...

Abstract Plasmonic solid‐state nanopores with tunable hole diameters can be prepared via a photocatalytic effect resulting from the enhanced electromagnetic (EM) field inside metallic ring on top of dielectric nanotube. Under white light illumination, plasmon‐enhanced EM‐field induces site‐selective metal nucleation and growth within ring. This approach is used to prepare Au bimetallic Au–Ag nano‐rings demonstrate reduction initial inner diameter nanopore down 4 nm. The tunability enable...

Carbon nanotube (CNT)-based chemiresistive gas sensors are known to not fully recover the baseline after exposure. This is why often heat applied thermally activate sensor and improve desorption process occurring at surface. In this letter, we combine single-walled CNTs (SWCNTs) with conjugated polymers (CPs), i.e., Poly(3-hexylthiophene)(P3HT), realize improved recovery. Five configurations were fabricated diverse positions of sensing material layers respect interdigitated electrodes...

Furaneol is a widely used flavoring agent, which can be naturally found in different products, such as strawberries or thermally processed foods. This why it extremely important to detect furaneol the food industry using ultra-sensitive, stable, and selective sensors. In this context, electrochemical biosensors are particularly attractive they provide cheap reliable alternative measurement device. Carbon nanotubes (CNTs) silver nanoparticles (AgNPs) have been extensively investigated...

Aptamer-based sensing of small molecules such as dopamine and serotonin in the brain, requires characterization specific aptamer sequences solutions mimicking vivo environment with physiological ionic concentrations. In particular, divalent cations (Mg2+ Ca2+) present brain fluid, have been shown to affect conformational dynamics aptamers upon target recognition. Thus, for biosensors that transduce structure switching signal response, it is critical interrogate influence on each unique...

Abstract Solid‐state nanopore gating inspired by biological ion channels is gaining increasing traction due to a large range of applications in biosensing and drug delivery. Integration stimuli‐responsive molecules such as poly(N‐isopropylacrylamide) (PNIPAM) inside nanopores can enable temperature‐dependent gating, which so far has only been demonstrated using external heaters. In this work, plasmonic resonators are combined the architecture with PNIPAM optical individual or multiple...

In this work, we present a novel, sensitive, easy-to-fabricate, flexible amperometric sensor constituted by screen-printed silver (Ag) electrodes functionalized with copper (Cu) film electrodeposited on top of spray coated network single-walled carbon nanotubes (SWCNTs). The Cu/SWCNTs/Ag electrode showed excellent catalytic activity towards the electro-reduction nitrate ions at neutral pH significant increase in cathodic peak currents comparison without SWCNTs (Cu/Ag). developed wide linear...

Abstract Triboelectric nanogenerators (TENGs) have demonstrated great promise especially for the realization of self‐powered biomedical sensors. Nevertheless, developing TENG sensors able to detect broad range biomechanical movements experienced on human body is still a challenge. Herein, unique ridge‐structured device sensitive wide forces reported (i.e., low‐forced pulse monitoring high‐forced gait monitoring). The composed thermoplastic polyurethane layer sandwiched between two textured...

Carbon nanotubes are a promising sensing material for bio-transduction devices, due to their unique electrical properties, nanosize, bio-compatibility, and simple low-cost processability. In this contribution, we present two classes of devices (i.e., electrolyte-gated field-effect transistor-based sensors gas sensors) fabricated by facile scalable spray deposition water-based carbon nanotube inks. The developed platforms have been employed the detection several analytes different...

In this work, we realized a printed immunosensor based on competitive enzyme-linked immunosorbent assay (ELISA) to allow histamine detection. We investigated the effect of modifying electrodes with spray-deposited poly(3,4-ethyldioxythiophene)poly(styrenesulfunate) (PEDOT:PSS) and single walled carbon nanotube (SWCNT) films. Cyclic voltammetry (CV) was used characterize sensor performance in terms electron transfer kinetics prove an enhancement electrode active surface area up 29.1%, due use...

In this work, we present a novel flexible amperometric sensor for nitrate detection, based on silver (Ag) working electrode modified with single-walled carbon nanotubes (SWCNTs) and copper (Cu). A simple low-cost fabrication technique combining printing electrochemical deposition was used: after spray of SWCNTs the screen-printed Ag electrode, Cu electrodeposited. The performance our sensors analyzed compared to reference fabricated without (Cu/Ag), proving capability improve sensitivity...

Ochratoxin A (OTA) is one of the most widely known and highly toxic types mycotoxins, able to contaminate different food products result in serious health problems for consumers. It therefore important detect OTA using fast, simple reliable techniques. In this work, bendable stretchable selective biosensors were screen-printed on Polyethylene terephthalate (PET) Poly(dimethylsiloxane) (PDMS), respectively. The working electrodes (WE) coated with single-walled carbon nanotubes (SWCNTs) then...

Ammonia (NH <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> ) is potentially a hazardous gas that can be threat to both human health and the environment. This why, sensitive, fast, low-cost, accurate sensing techniques for ammonia detection are extremely needed, especially if on soft substrates Nowadays, wide range of sensors based single-walled carbon nanotubes (SWCNTs) has been reported. Nevertheless, most reported solutions (mostly...

We show that plasmonic solid-state nanopores with tunable hole diameter can be prepared via a photocatalytic effect resulting from the enhanced electromagnetic field inside metallic ring on top of dielectric nanotube. Under white light illumination, maximum intensity in these nanorings induces site selective metal nucleation and growth. used this approach to prepare bare Au bimetallic Au-Ag demonstrate reduction initial inner nanopore down 4 nanometers. This process applied over large arrays...

The polymer thin-film memristors were fabricated by means of a simple and low-cost spray coating printing technique, later characterized. realized polymer-based present sandwich structure composed an indium tin oxide (ITO) bottom electrode, biocompatible polymeric resistive layer consist poly(3,4 ethyldioxythio-phene)poly(styrenesulfunate) (PEDOT:PSS) poly(vinyl alcohol) (PVA), gold top electrode. Atomic force microscopy was used to perform topographical analysis the spray-coated layer....

There is a high current interest for novel plasmonic platforms and materials able to extend their applicability into the ultraviolet (UV) region of electromagnetic spectrum. In UV it possible explore spectral properties biomolecules with small cross section in visible range. However, most used metals plasmonics have resonances at wavelengths > 350 nm. Aluminum rhodium are two interesting candidate plasmonics, this work we developed simple low-cost preparation functional substrates based on...

Non-porous aluminium decorated with rhodium nanoparticles show potential as plasmonic substrates for UV SERS. Adenine (absorption maxima ∼250 nm) makes an ideal resonant analyte probing using a 266 nm laser.