A5032202893- Toxic Organic Pollutants Impact
- Marine animal studies overview
- Mercury impact and mitigation studies
- Cancer, Hypoxia, and Metabolism
- Effects and risks of endocrine disrupting chemicals
- Adrenal and Paraganglionic Tumors
- Coral and Marine Ecosystems Studies
- Hormonal Regulation and Hypertension
- Vitamin K Research Studies
- Fish Biology and Ecology Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Pituitary Gland Disorders and Treatments
- Fish Ecology and Management Studies
- Ichthyology and Marine Biology
- Isotope Analysis in Ecology
- Microplastics and Plastic Pollution
- Ocean Acidification Effects and Responses
- Per- and polyfluoroalkyl substances research
- Neuropeptides and Animal Physiology
Zoological Society of London
2019-2025
University College London
2023-2025
Brunel University of London
2020-2021
Great Western Hospital
2006
Kentucky Science Center
1992
Germline mutations of the SDHD, SDHB and SDHC genes, encoding three four subunits succinate dehydrogenase, are a major cause hereditary paraganglioma pheochromocytoma, demonstrate that these genes classic tumor suppressors. Succinate dehydrogenase is heterotetrameric protein complex component both Krebs cycle mitochondrial respiratory chain (succinate:ubiquinone oxidoreductase or II).Using conformation sensitive gel electrophoresis (CSGE) direct DNA sequencing to analyse genomic from...
Apex predators are good indicators of environmental pollution since they relatively long-lived and their high trophic position spatiotemporal exposure to chemicals provides insights into the persistent, bioaccumulative toxic (PBT) properties chemicals. Although monitoring data from apex can considerably support chemicals' management, there is a lack pan-European studies, longer-term in organisms higher levels. The present study investigated occurrence contaminants emerging concern (CECs) 67...
Despite their ban and restriction under the 2001 Stockholm Convention, persistent organic pollutants (POPs) are still widespread pervasive in environment. Releases of these toxic bioaccumulative chemicals ongoing, contribution to population declines marine mammals is global concern. To safeguard survival, it paramount importance understand effectiveness mitigation measures. Using one world's largest strandings data sets, we combine published unpublished examine pollutant concentrations 11...
Polychlorinated biphenyls (PCBs) are toxic, persistent, and lipophilic chemical compounds that accumulate to high levels in harbor porpoises (Phocoena phocoena) other cetaceans. It is important monitor PCBs wildlife, particularly highly exposed populations understand if concentrations declining how relate toxicological thresholds indices of health like infectious disease mortality. Here we show, using generalized additive models tissue samples 814 U.K.-stranded collected between 1990 2017,...
Polychlorinated biphenyls (PCBs) are a group of 209 persistent and bio-accumulative toxic pollutants present as complex mixtures in human animal tissues. Harbor porpoises accumulate some the highest levels PCBs because they long-lived mammals that feed at high trophic level. Studies typically use sum suite individual chlorobiphenyl congeners (CBs) to investigate wildlife. However, effects thresholds CB differ, therefore population health risks exposure may be under or over-estimated...
Polychlorinated biphenyls (PCBs) are highly toxic and persistent aquatic pollutants that known to bioaccumulate in a variety of marine mammals. They have been associated with reduced recruitment rates population declines multiple species. Evidence date documents effects PCB exposures on female reproduction, but few studies investigated whether exposure impacts male fertility. Using blubber tissue samples 99 adult 168 juvenile UK-stranded harbour porpoises (Phocoena phocoena) collected...
This report describes a rare case of patient with increased urinary dopamine excretion in association bilateral carotid body tumours. Excretion adrenaline, noradrenaline, metadrenaline, normetadrenaline and 4-hydroxy-3-methoxymandelic acid (HMMA) were within the reference ranges, an (123)I-meta-iodobenzylguanidine (MIBG) scan showed uptake neck masses, no other abnormal anywhere else body. The is being managed conservatively as tumours are not amenable to resection on account their size...
Abstract Three Odontaspis ferox (confirmed by mtDNA barcoding) were found in the English Channel and Celtic Sea 2023 at Lepe, UK (50.7846, −1.3508), Kilmore Quay, Ireland (52.1714, −6.5937), Lyme Bay, (50.6448, −2.9302). These are first records of O. either country, extend species' range over three degrees latitude, to >52° N. They ~275 (female), 433 293 cm (male) total length, respectively. continue a series new records, possibly indicative climate change−induced shift range.
Polychlorinated biphenyls (PCBs) are a group of 209 persistent and bio-accumulative toxic pollutants present as complex mixtures in human animal tissues. Harbor porpoises accumulate some the highest levels PCBs because they long-lived mammals that feed at high trophic level. Studies typically use sum suite individual chlorobiphenyl congeners (CBs) to investigate wildlife. However, effects thresholds CB differ, therefore population health risks exposure may be under or over-estimated...