A5000066339- Forensic Anthropology and Bioarchaeology Studies
- Reproductive biology and impacts on aquatic species
- Forensic and Genetic Research
- Social Sciences and Governance
- Calcium Carbonate Crystallization and Inhibition
- Bone Tissue Engineering Materials
- Race, Genetics, and Society
- Hormonal and reproductive studies
- Archaeology and ancient environmental studies
- Advanced biosensing and bioanalysis techniques
- Multiculturalism, Politics, Migration, Gender
- Aquaculture disease management and microbiota
- Chromosomal and Genetic Variations
- Effects and risks of endocrine disrupting chemicals
- Sperm and Testicular Function
- Healthcare Systems and Practices
- Pleistocene-Era Hominins and Archaeology
- Aquaculture Nutrition and Growth
- Genetics, Aging, and Longevity in Model Organisms
- French Urban and Social Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Natural Antidiabetic Agents Studies
- Regional resilience and development
- Bone and Dental Protein Studies
- COVID-19 Pandemic Impacts
Uppsala University
2020-2025
Ministère du travail, de l'emploi et de l'insertion
2019
Sorbonne Université
2006-2013
Centre National de la Recherche Scientifique
2004-2013
University of Bergen
2006-2010
In many teleosts, the stimulatory control of gonadotrope axis by GnRH is opposed an inhibitory dopamine (DA). The functional importance this pathway differs widely from one teleostean species to another. zebrafish (Danio rerio) a teleost fish that has become increasingly popular as experimental vertebrate model. However, role DA in neuroendocrine its reproduction never been studied. Here authors evaluated sexually regressed female effects vivo treatments with D2 receptor (D2-R) antagonist...
Abstract The expansion of people speaking Bantu languages is the most dramatic demographic event in Late Holocene Africa and fundamentally reshaped linguistic, cultural biological landscape continent 1–7 . With a comprehensive genomic dataset, including newly generated data modern-day ancient DNA from previously unsampled regions Africa, we contribute insights into this that started 6,000–4,000 years ago western Africa. We genotyped 1,763 participants, 1,526 speakers 147 populations across...
The disposable soma theory is a central tenet of the biology aging where germline immortality comes at cost an [T. B. L. Kirkwood, Nature 270, 301–304 (1977); T. Proc. R. Soc. Lond. B Biol. Sci. 205, 531–546 (1979); S. N. Austad, 408, 233–238 (2000)]. Limited resources and possible trade-off between repair maintenance germ cells growth may explain deterioration over time. Here we show that removal allows accelerated somatic healing under stress. We tested “the expensive line” hypothesis by...
A study was conducted to assess the effect of substituting high levels dietary fish oil (FO) and fishmeal (FM) for vegetable (VO) plant protein (PP) on intestinal arachidonic acid (AA) cascade in carnivorous species Atlantic salmon. Four diets were fed salmon over a period 12 months, including control FMFO diet, with varying replacements plant-derived ingredients: 80 % PP 35 VO; 40 70 %VO. Subsequently, examined pre- (0 h) post- (1 acute stress blood parameters bioactive lipidic mediators...
Atlantic salmon (Salmo salar L.) is one of the most economically important cultured fish and also a key model species in nutrition. During digestion, dietary proteins are enzymatically cleaved fraction degradation products form di- tripeptides translocates from intestinal lumen into enterocyte via Peptide Transporter 1 (PepT1). With this mind, full-length cDNA encoding PepT1 (asPepT1) was cloned functionally characterized. When overexpressed Xenopus laevis oocytes, asPepT1 operated as...
Abstract Environmental factors affect not only paternal condition but may translate into the following generations where sperm-mediated small RNAs (sRNAs) can contribute to transmission of effects. sRNAs play a key role in male germ line genome maintenance and repair, particularly response environmental stress resulting increase transposable element (TE) activity. Here, we investigated how social environment (high competition, low competition) zebrafish Danio rerio affects sperm these are...
Africa harbors the richest diversity of mitochondrial DNA lineages, reflecting its central role in human evolutionary history. Early studies mtDNA variation provided first genetic evidence for African origin modern humans. With complete genome sequencing, we can now reconstruct maternal lineages with high resolution, yet large parts continent remain underrepresented. Using a newly developed long-range sequencing assay, generated 1,288 genomes from 14 countries across sub-Saharan Africa,...
Abstract With the largest genomic dataset to date of Bantu-speaking populations, including newly generated data modern-day and ancient DNA from previously unsampled regions in Africa, we shed fresh light on expansion peoples speaking Bantu languages that started ∼4000 years ago western Africa. We have genotyped 1,740 participants, 1,487 speakers 143 populations across 14 African countries, whole-genome sequences 12 Late Iron Age individuals. Our results show received significant gene-flow...
The Organisation for Economic Cooperation and Development (OECD) is currently validating a short-term fish screening protocol endocrine disrupters (estrogens, androgens, their antagonists aromatase inhibitors), using three core species: fathead minnow, Japanese medaka, zebrafish. main endpoints proposed the first phase of validation screen are vitellogenin (VTG) concentration, gross morphology (secondary sexual characteristics gonado-somatic index), gonadal histopathology. A similar...
Various skeletons from the uThukela region of uKhahlamba-Drakensberg Mountains South Africa were excavated rock shelters there during early part twentieth century, with limited accompanying data or analysis. This paper analyses and reports on nine such graves (eight which contained human remains), 1931 near Cathkin Peak. The remains are currently housed in Raymond A. Dart Archaeological Human Remains Collection, University Witwatersrand, Johannesburg. Most radiocarbon-dated to between...
The Later Stone Age (LSA) site of Zuurberg in the Cape Fold Mountains South Africa was excavated 1920s by F.W. FitzSimons. As with his other excavations, not much is known about exact provenance and detailed archaeological context remains. This paper reports re-analysis dating human skeletal remains from Zuurberg. were commingled but here sorted according to previously published sources. eight individuals are present, which only one (Zg3) fairly complete. assemblage includes four older...
Abstract The South African Coloured (SAC) population, a prominent admixed population in Africa, reflects centuries of migration, admixture, and historical segregation. Descendants local Khoe-San Bantu-speaking populations, European settlers, enslaved individuals from Africa Asia, SAC embody diverse ancestries. This study investigates the genetic makeup individuals, utilizing autosomal genotypes, mitochondrial DNA Y-chromosome data. We analyze new genotype data for 125 seven locations. Our...
Environmental factors affect not only paternal condition but may translate into the following generations where sperm-mediated small RNAs (sRNAs) can contribute to transmission of effects. SRNAs play a key role in male germ line genome maintenance and repair, particularly response environmental stress resulting increase transposable element (TE) activity. Here, we investigated how social environment (high competition, low competition) zebrafish Danio rerio affects sperm these are linked gene...