Brigitte Gerstl

ORCID: 0000-0003-1848-056X
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About
Contact & Profiles
Research Areas
  • Reproductive Biology and Fertility
  • Ovarian function and disorders
  • Reproductive Health and Technologies
  • Organ and Tissue Transplantation Research
  • Sperm and Testicular Function
  • Body Image and Dysmorphia Studies
  • Child and Adolescent Psychosocial and Emotional Development
  • Ovarian cancer diagnosis and treatment
  • Cancer Risks and Factors
  • Radiomics and Machine Learning in Medical Imaging
  • Endometrial and Cervical Cancer Treatments
  • Renal and related cancers
  • Childhood Cancer Survivors' Quality of Life
  • Autism Spectrum Disorder Research
  • Female Genital Mutilation/Cutting Issues
  • Obsessive-Compulsive Spectrum Disorders
  • Genital Health and Disease
  • Organ Donation and Transplantation
  • Emergency and Acute Care Studies
  • Social Media in Health Education
  • Urinary and Genital Oncology Studies
  • Maternal Mental Health During Pregnancy and Postpartum
  • Reconstructive Surgery and Microvascular Techniques
  • Gender, Feminism, and Media
  • Adrenal and Paraganglionic Tumors

UNSW Sydney
2016-2025

Royal Hospital for Women
2023-2025

South Eastern Sydney Local Health District
2025

New South Wales Department of Health
2025

Ingham Institute
2022-2024

South Western Sydney Local Health District
2023-2024

Sydney Children's Hospital
2015-2023

Cancer Institute of New South Wales
2022

Yashoda Hospital
2021-2022

Prince of Wales Hospital
2015-2020

Fertility preservation (FP) is an important quality of life issue for cancer survivors reproductive age. Despite the existence broad international guidelines, delivery oncofertility care, particularly amongst paediatric, adolescent and young adult patients, remains a challenge healthcare professionals (HCPs). The care variable uptake utilization FP low. Available guidelines fall short in providing adequate detail on how models (MOC) allow real-world application by HCPs.

10.1093/humupd/dmy038 article EN cc-by-nc Human Reproduction Update 2018-10-25

Fertility preservation in the cancer setting, known as oncofertility, is a field that requires cross-disciplinary interaction between physicians, basic scientists, clinical researchers, ethicists, lawyers, educators, and religious leaders. Funded by National Institutes of Health, Oncofertility Consortium (OC) was formed to be scientifically grounded, transparent, altruistic resource, both intellectual monetary, for building this new practice capable addressing unique needs young patients...

10.1200/jgo.2015.000307 article EN cc-by-nc-nd Journal of Global Oncology 2015-12-24

The aim is to report the results of Australia's first uterus transplantation (UTx).Following long-standing collaboration between Swedish and Australian teams, Human Research Ethics approval was obtained perform six UTx procedures in a collaborative multi-site research study (Western Sydney Local District Health 2019/ETH13038), including Royal Hospital for Women, Prince Wales Hospital, Westmead New Souh Wales. Surgeries were approved both live donor (LD) deceased models with inaugural...

10.1111/ajo.13678 article EN cc-by-nc-nd Australian and New Zealand Journal of Obstetrics and Gynaecology 2023-04-08

Aim Uterus transplantation (UTx) is an emerging treatment option for women with uterine factor infertility (UFI) or the absence of a functional uterus. This study protocol first human UTx clinical trial in Australia. Materials and Methods outlines approved training program used to plan, diagnose, screen, treat patients who may be eligible using living deceased donors. multi‐site research includes three tertiary hospital sites within New South Wales (NSW), Australia – Prince Wales, Royal...

10.1111/ajo.13810 article EN cc-by-nc-nd Australian and New Zealand Journal of Obstetrics and Gynaecology 2024-03-28

Despite international evidence about fertility preservation (FP), several barriers still prevent the implementation of equitable FP practice. Currently, oncofertility competencies do not exist. The aim this study was to develop an competency framework that defines key components care, develops a model for prioritizing service development, and roles health care professionals (HCPs) play.A quantitative modified Delphi methodology used conduct two rounds electronic survey, querying synthesizing...

10.1634/theoncologist.2019-0043 article EN The Oncologist 2019-05-30

ABSTRACT Objective This study aims to investigate the psychological characteristics, motivations and experiences of potential living donors assessed for first uterus transplant (UTx) clinical trial in Australia. Design Mixed methods study. Setting Tertiary hospital. Patient(s) Seven female UTx donors. Intervention(s) A mixed‐methods design was used evaluate seven self‐referred program. Potential underwent rigorous screening, including self‐reported assessments. Additionally, five...

10.1111/ajo.13934 article EN Australian and New Zealand Journal of Obstetrics and Gynaecology 2025-01-21

Background Uterus transplant now offers an alternative deceased donation treatment option for women with uterine infertility. Limited research exists on religious opinions that may impact the addition of uterus to current multi-organ donor programs Objective To explore acceptability transplantation and across different groups. Design A cross-sectional survey 2,497 participants was conducted between October 2022 January 2023 in NSW Australia. Australia is a culturally religiously diverse...

10.3389/frtra.2025.1536754 article EN cc-by Frontiers in Transplantation 2025-02-28

Abstract Objective To report the first live birth following uterus transplantation in Australia. Study design Case report. Setting, participant The research study program at Royal Hospital for Women, Prince of Wales Hospital, and Westmead Sydney. Main outcome measures Clinical course after transplantation; subsequent pregnancy until delivery. Results immunosuppression regimen on 10 January 2023 was similar to that used low immunologic risk kidney transplantation. It included induction...

10.5694/mja2.52682 article EN cc-by The Medical Journal of Australia 2025-05-23

In Australia and New Zealand, there has not been a national systematic development of oncofertility services for cancer patients reproductive age although many fertility centers have independently developed services. A number barriers exist to the these services, including lack clear referral pathways, communication between clinicians about preservation, differences in knowledge base risk treatment causing infertility preservation options, health insurance funding covering all aspects...

10.1089/jayao.2015.0056 article EN Journal of Adolescent and Young Adult Oncology 2016-03-16

<br><b>Background:</b> Ovarian reserve declines with age. However, there are considerable ethnic differences in the decline of ovarian between individuals. <b>Aim:</b> This study aimed to make age-specific percentile charts anti-Mullerian hormone (AMH) and antral follicle count (AFC) Indian infertile women find proportion young low reserve. <b>Setting Design:</b> was a retrospective data analysis AMH AFC 5525 from August 2015 December 2018. <b>Materials Methods:</b> Infertile aged 20–44...

10.4103/jhrs.jhrs_65_21 article EN cc-by-nc-sa Journal of Human Reproductive Sciences 2021-01-01

Abstract Purpose Cancer survivors may experience infertility and sexual dysfunction following cancer treatment. Survivors report significant gaps in oncofertility care consider these issues important, yet they are rarely discussed. The aims of this study were to evaluate survivors’ reproductive complications across age groups identify specific at risk for complications. Method We data collected from cancers diagnosed childhood, adolescence adulthood the development piloting a survivorship...

10.1007/s11764-023-01349-6 article EN cc-by Journal of Cancer Survivorship 2023-03-29

Phaeochromocytoma (PC) and paraganglioma (PGL) syndromes associated with germline pathogenic variants are high morbidity mortality. Establishing genotype–phenotype correlations within a young population is challenging due to their rare occurrence. Objective To describe in paediatric adolescent patients diagnosed PC/PGL. establish the incidence of PC/PGL prevalence this group. Study design We conducted cross-sectional study aged 0–21 years old who were reviewed Familial Cancer Services New...

10.1136/archdischild-2023-325419 article EN Archives of Disease in Childhood 2023-12-06

Background Brief intervention services provide rapid, mobile and flexible short-term delivery of interventions to resolve mental health crises. These may an alternative pathway the emergency department or in-patient psychiatric for children young people (CYP), presenting with acute condition. Aims To synthesise evidence on effectiveness brief in improving outcomes CYP (0–17 years) Method A systematic literature search was conducted, studies’ methodological quality assessed. Five databases...

10.1192/bjo.2024.25 article EN cc-by-nc-nd BJPsych Open 2024-04-11

Abstract Introduction Uterus transplant (UTx) has emerged as a groundbreaking solution for individuals with uterine factor infertility (UFI). This study is the first in Australia to explore psychosocial functioning of potential recipients assessed nation's initial UTx clinical trial and compare their psychological profiles those from international trials. Material Methods mixed methods prospective incorporating standardized measures semi‐structured interviews. Conducted at tertiary hospital...

10.1111/aogs.14974 article EN cc-by-nc Acta Obstetricia Et Gynecologica Scandinavica 2024-09-26

While uterus transplantation offers a promising treatment option for women with uterine factor infertility (UFI), the potential graft failure and lack of organ availability could have subsequent psychological repercussions women. Exploring baseline well-being UFI who become transplant recipients is essential to identify specific challenges be considered prior transplantation. can congenital absence, namely Mayer-Rokitansky-Küster-Hauser syndrome (MRKH), or acquired absence (hysterectomy).

10.1111/ajo.13895 article EN Australian and New Zealand Journal of Obstetrics and Gynaecology 2024-11-12

Fertility preservation in the cancer setting, known as oncofertility, is a field that requires cross-disciplinary interaction between physicians, basic scientists, clinical researchers, ethicists, lawyers, educators, and religious leaders. Funded by National Institutes of Health, Oncofertility Consortium (OC) was formed to be scientifically grounded, transparent, altruistic resource, both intellectual monetary, for building this new practice capable addressing unique needs young patients...

10.1200/go.22.00007 article EN cc-by-nc-nd JCO Global Oncology 2020-11-01
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