- Additive Manufacturing and 3D Printing Technologies
- 3D Printing in Biomedical Research
- Manufacturing Process and Optimization
- Additive Manufacturing Materials and Processes
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- Metallurgy and Material Forming
- Perovskite Materials and Applications
- Liver physiology and pathology
- Quantum Dots Synthesis And Properties
- Robot Manipulation and Learning
- Advanced Surface Polishing Techniques
- Data Mining Algorithms and Applications
- Mechanical stress and fatigue analysis
- Mechanical Failure Analysis and Simulation
- Cellular and Composite Structures
- Robotic Locomotion and Control
- Advanced Electron Microscopy Techniques and Applications
- Welding Techniques and Residual Stresses
- Titanium Alloys Microstructure and Properties
- Metal Forming Simulation Techniques
- Advanced Computational Techniques and Applications
- Mesenchymal stem cell research
- Pesticide Residue Analysis and Safety
Guangzhou University
2025
Gansu Agricultural University
2024
Tsinghua University
2015-2024
University of Waterloo
2024
Chinese People's Liberation Army
2024
Shanghai Eighth People Hospital
2024
Ministry of Education of the People's Republic of China
2020-2024
Hainan Branch of People's Liberation Army General Hospital
2024
Aerospace Research Institute of Materials and Processing Technology
2015-2023
University of Science and Technology Beijing
2023
Using rapid prototyping technology, three-dimensional (3D) structures composed of hepatocytes and gelatin hydrogel have been formed. This technique employs a highly accurate 3D micropositioning system with pressure-controlled syringe to deposit cell/biomaterial lateral resolution 10 µm. The pressure-activated micro-syringe is equipped fine-bore exit needle for which wide variety patterns different arrays channels (through-holes) were created. More than 30 layers hepatocyte/gelatin mixture...
With the rapid development of Additive Manufacturing (AM) technology in past 30 years, AM has been shifting from prototyping to advanced manufacturing functional components industry. Intellectualization and industrialization process equipment could be bottlenecks wide industrial applications future, which have highlighted this paper, aiming at describing technological research roadmaps for next 5 10 years. According data flow value chains technologies, state-of-art design methodology,...
There is a need for rapid fabrication of tissue or organs with well-defined structures and functions in regenerative medicine. Two patterns cell/matrix constructs containing hepatic cells, gelatin fibrinogen were successfully created by automated prototyping techniques stabilized thrombin. No apparent cell damage was found during the process. Mechanical characterization demonstrated that 1:1 ratio gelatin/fibrin mixture had greatest elasticity modulus compressive strength. Microscopic...
The rapid prototyping and manufacturing technology (RPM), is an integration of many different disciplines. It based on advanced dispersed-accumulated forming principle originated from 1980s. generates entity by first a series layers according to the dispersed section information digital model, then piling formed sequentially together. capable parts with complicated structures non-homogeneous materials. Traditional RPM techniques are mainly used as prototypes in product invention process,...
Human adipose-derived stem cells (hADSC) encapsulated in alginate and alginate/gelatin microspheres with adjustable properties were fabricated via an improved microsphere generating device. The mechanism of the device, porous property, swelling behavior hADSC proliferation as well adipogenic differentiation studied extensively. Microspheres high-ratio evenly distributed adipocytes could be obtained by utilizing proper matrix material manufacturing parameters. adipocyte/hADSC a sound vitro...
The existing in vitro models for antitumor drug screening have great limitations. Many compounds that inhibit 2D cultured cells do not exhibit the same pharmacological effects vivo, thereby wasting human and material resources as well time during development. Therefore, developing new is critical. 3D bioprinting technology has greater advantages constructing tissue compared with sandwich culture organoid construction. Here, we used to construct a model HepG2 (3DP-HepG2). biological...
The bonding performance of epoxy resin adhesives plays a critical role in ensuring interlayer adhesion and long-term durability steel bridge deck pavements. However, the construction environment temperature curing time significantly influence properties adhesives. To address this issue, systematic evaluations tack-free were conducted. results demonstrate that under identical durations, tensile bond strength between layer plate increases with higher temperatures. Similarly, at constant...
An organ manufacturing technique was developed that enables the formation of cell/extracellular matrix (ECM) complexes for in vitro or vivo growth. In this study, a three-dimensional (3D) structure composed hepatocytes and gelatin/alginate hydrogel made using cell assembler-I apparatus to thoroughly control assembling. Hepatocytes ECM were constructed into 10 X 3mm 3 structures according designed pattern. The embedded remained viable performed biological functions construct more than 12...
Brain tissue engineering has now emerged as one of the most promising treatments for traumatic brain injury. In this article, two groups three-dimensional (3D) hydrogel structures composed gelatin and gelatin/hyaluronan have been formed using our 3D cell assembly technique in vivo study rats, order to investigate their effects reparation injury central nervous system (CNS). The were implanted into cortical defects created rat brains, abilities improve reconstruction then evaluated. After 4,...
Exercise prescriptions play a vital role in the prevention and treatment of chronic diseases. A consensus regarding exercise prescription is important for physical health. The "Consensus statement Chinese experts on prescription" (hereinafter referred to as "Expert Consensus") divides into two categories: fitness medical prescription. Traditional exercises, risk, prescription, basic precautions are explained.
Abstract A new type of collagen/chitosan/heparin matrix, fabricated by gelation collagen/chitosan with heparin sodium containing ammonia, was produced to construct livers tissue engineering and regenerative engineering. The obtained matrix found be highly porous, swelled rapidly in PBS solution stable vitro for at least 60 days collagenase/lysozyme buffered aqueous (PBS, pH 7.4) 37°C. resulted a superior blood compatibility compared the ammonia-treated collagen matrices. morphology behavior...
Engineering adipose tissue that has the ability to engraft and establish a vascular supply is laudable goal broad clinical relevance, particularly for reconstruction. In this article, we developed novel microtissues from surface-coated adipocyte/collagen/alginate microspheres human umbilical vein endothelial cells (HUVECs) co-cultures resembled components structure of natural tissue. Firstly, collagen/alginate hydrogel embedded with viable adipocytes were obtained mimic fat lobules....
It is of great importance to investigate the crystallization organometallic perovskite from solution for enhancing performance solar cells. Here, this study develops a facile method in situ observation and growth methylammonium lead iodide (MAPbI 3 ) microdroplets ejected by an alternating viscous inertial force jetting method. found that there are two modes when MAPbI grows CH NH I (MAI)/PbI 2 / N , ‐dimethylformamide (DMF) solution: needle precursors granular perovskites. Generally, Lewis...
Perovskite structures of organic and inorganic halides are peculiar with many interesting properties. Using their photoelectric effect, the have been used in photocells, sensors, light-emitting diodes. In conventional perovskite film crystallization, which is a one-step method, MAPbI3 crystals form disordered needlelike at room temperature. Such crystal films rough surfaces low coverage to substrate, resulting insignificant effects. With assistance an electric field three-dimensional (3D)...
Low-dimensional metal halide perovskites have unique optical and electrical properties that render them attractive for the design of diluted magnetic semiconductors. However, nature dopant-exciton exchange interactions result in spin-polarization host-lattice charge carriers as a basis spintronics remains unexplored. Here, we investigate Mn