A5035101973- Marine Sponges and Natural Products
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Bioactive Compounds and Antitumor Agents
- Microbial Natural Products and Biosynthesis
- Phytochemistry and Bioactive Compounds
- Seaweed-derived Bioactive Compounds
- Traditional and Medicinal Uses of Annonaceae
- Phytochemical compounds biological activities
- Echinoderm biology and ecology
- Essential Oils and Antimicrobial Activity
- Phytochemical Studies and Bioactivities
- Biological Activity of Diterpenoids and Biflavonoids
- Phytochemicals and Antioxidant Activities
- Synthesis and Biological Activity
- Sesquiterpenes and Asteraceae Studies
- Marine Biology and Environmental Chemistry
- Plant biochemistry and biosynthesis
- Bioactive Natural Diterpenoids Research
- Research studies in Vietnam
- Phytochemistry and Bioactivity Studies
- Bioactive natural compounds
- Chemical synthesis and alkaloids
- Medicinal Plants and Neuroprotection
- Morinda citrifolia extract uses
Vietnam Academy of Science and Technology
2016-2025
Waseda University
2007-2025
University Health Network
2025
Marie Curie
2025
Vietnam National University Ho Chi Minh City
2011-2024
Vietnam Academy of Social Sciences
1987-2024
Hanoi University of Science and Technology
2017-2024
Hue University
2024
Industrial University of Ho Chi Minh City
2021-2024
Duy Tan University
2024
Fourteen cucurbitane-type triterpene glycosides (1—14) were isolated from a methanol extract of Momordica charantia fruits, including three new compounds, charantosides A—C (1, 5, 6). Their structures elucidated by chemical and spectroscopic methods. All compounds evaluated for α-glucosidase inhibitory effect. Of which, 12 13 showed moderate activity against α-glucosidase. Whereas, 2, 3, 6—11, 14 weak activity, 1, 4, 5 inactive.
In this work, we present magnetic nanoparticles based on iron oxide doped with zinc synthesized using the wet co-precipitation method for environmental application. The morphology of samples was revealed by SEM and TEM, which showed particles granular shape size about 15 nm. specific surface areas materials BET were within range 85.7 to 101.5 m2 g−1 depending content in superparamagnetic (SPIONs). Magnetometry performed determine properties particles, indicating superparamagnetism....
Korean ginseng (Panax C.A. Meyer) has been extensively used as a functional food for thousands of years. This study with the aim to evaluate potential P. flower components medicinal properties resulted in identification three new dammarane-type saponins, named floralginsenosides Ka−Kc (1−3), along seventeen known ones (4−20). Their structures were elucidated on basis chemical and spectroscopic methods, their antioxidant activities evaluated by intracellular ROS radical scavenging DCF-DA...
Four new asterosaponins, astrosteriosides A–D (1–3 and 5), two known compounds, psilasteroside (4) marthasteroside B (6), were isolated from the MeOH extract of edible Vietnamese starfish Astropecten monacanthus. Their structures elucidated by chemical spectroscopic methods including FTICRMS 1D 2D NMR experiments. The effects extracts compounds on pro-inflammatory cytokines evaluated measuring production IL-12 p40, IL-6, TNF-α in LPS-stimulated bone marrow-derived dendritic cells. Compounds...
Inflammation is important in biomedical research, because it plays a key role inflammatory diseases including rheumatoid arthritis and other forms of arthritis, diabetes, heart disease, irritable bowel syndrome, Alzheimer’s Parkinson’s allergies, asthma, even cancer. In the present study, we describe inhibitory effect crude extracts steroids isolated from starfish Astropecten polyacanthus on pro-inflammatory cytokine (Interleukin-12 (IL-12) p40, interleukin-6 (IL-6), tumor necrosis factor α...
In this work, a nanostructural composite based on the superparamagnetic iron oxide nanoparticles (SPIONs) coated with hydroxyapatite (HAp) was demonstrated as an effective adsorbent for removal of Congo red (CR) from aqueous solutions.Prior to its application model pollutant, morphology, crystallinity, specific surface area, chemical composition, and magnetic properties were characterized several techniques, including scanning electron microscopy, transmission Fourier-transform infrared...
Chemical investigation of the Vietnamese soft coral Sarcophyton mililatensis resulted in isolation four new cembranoid diterpenes, namely (-)-7beta-hydroxy-8alpha-methoxydeepoxysarcophytoxide (1), (+)-7beta,8beta-dihydroxydeepoxysarcophytoxide (2), (-)-17-hydroxysarcophytonin A (3) and sarcophytol V (4), along with two known compounds, (+)-sarcophine (5) sarcophytoxide (6). The NMR spectral data compounds were completely assigned by using a combination 2D experiments including (1)H-(1)H...
Nine new diterpenoids, termed sinumaximols A–I (1–3, 5–9, 12), together with three known compounds (4, 10, 11), were isolated from the methanol extract of soft coral Sinularia maxima. Their structures elucidated on basis extensive spectroscopic methods, including one-dimensional (1D) and two-dimensional (2D) nuclear magnetic resonance (NMR) Fourier transform ion cyclotron mass spectrometry (FT-ICR-MS). The evaluated for their inhibitory effects lipopolysaccharide (LPS)-stimulated production...
Various chromatographic separations of the aerial parts Scutellaria barbata afforded two new neoclerodane diterpenoids, scutebatas S and T (1 2), along with scutebata D (3). Their structures were elucidated by spectroscopic methods including high-resolution electrospray ionization mass spectrometry, 1D 2D NMR comparison literature values. Compounds 1 3 exhibited moderate cytotoxic activities against HL-60 (promyeloblast) human cancer cells. Weak effects toward four tested cell lines KB...