A5101719145- Phytochemicals and Antioxidant Activities
- Food Quality and Safety Studies
- Ginseng Biological Effects and Applications
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Genomics, phytochemicals, and oxidative stress
- Bone Metabolism and Diseases
- Natural Antidiabetic Agents Studies
- Food composition and properties
- GABA and Rice Research
- Pharmacological Effects of Natural Compounds
- Phytoestrogen effects and research
- Biochemical effects in animals
- Protein Hydrolysis and Bioactive Peptides
- Diet, Metabolism, and Disease
- Essential Oils and Antimicrobial Activity
- Agriculture, Soil, Plant Science
- Garlic and Onion Studies
- Bioactive natural compounds
- Food Industry and Aquatic Biology
- Tea Polyphenols and Effects
- Ginger and Zingiberaceae research
- Free Radicals and Antioxidants
- Phytochemical and Pharmacological Studies
- Pharmacological Effects of Medicinal Plants
Ewha Womans University
2025
Hannam University
2010-2021
Hallym University
2015
Hyogo Medical University
2015
Chungnam National University
2014
Korea University Medical Center
2012
Framingham State University
2011
Food & Nutrition
2010
The objective of this study is to investigate the contributing effect nuclear transcription factor-erythroid 2-related factor 2 (Nrf2)-mediated signaling pathway on indirect antioxidant capacity caffeic acid phenethyl ester (CAPE) against oxidative stress in HepG2 cells. result an response element (ARE)-luciferase assay showed that CAPE stimulated ARE promoter activity resulting increased transcriptional and translational activities heme oxygenase-1 (HO-1). In addition, treatment enhanced...
Genistein, a phytoestrogen, has been demonstrated to have bone-sparing and antiresorptive effect. Genistein can inhibit the osteoclast formation of receptor activator nuclear factor-κB ligand (RANKL)-induced RAW 264.7 cells by preventing translocation (NF-κB), redox-sensitive factor, nucleus. Therefore, suppressive effect genistein on reactive oxygen species (ROS) level during differentiation mechanism associated with control ROS levels were investigated. The cellular antioxidant capacity...
The levels of cellular glutathione (GSH) and reactive oxygen species (ROS) simultaneously determined by fluorometric measurement, may provide important information on pro‐oxidative antioxidative balance. dual effect quercetin antioxidant pro‐oxidant activity was proposed from different studies. Our study demonstrated that acted as an in HepG2 cells when were treated with 10 100 μmol/L for 30 min, but a incubated at longer periods (12 24 h). Quercetin is capable reducing H 2 O ‐induced...
Mulberry (Morus alba L.) leaf extract (MLE) was investigated as a potent plant-derived α-glucosidase inhibitor with low α-amylase inhibitory activity. MLE prepared by heating in an autoclave at 121°C for 15 minutes, and its vitro vivo antihyperglycemic activities were investigated. The adverse side effects of analyzed measuring the weight volume cecum, stool color, starch content integrity intestinal transporting capacity. activity on that very weak compared acarbose. Sugar loading tests...
Fourteen cucurbitane-type triterpene glycosides (1—14) were isolated from a methanol extract of Momordica charantia fruits, including three new compounds, charantosides A—C (1, 5, 6). Their structures elucidated by chemical and spectroscopic methods. All compounds evaluated for α-glucosidase inhibitory effect. Of which, 12 13 showed moderate activity against α-glucosidase. Whereas, 2, 3, 6—11, 14 weak activity, 1, 4, 5 inactive.
Abstract: The biological activities of the mulberry ( Morus alba L.) leaf have been attributed to its flavonoid content. water extract (WEML) was prepared by autoclaving at 121 °C for 15 min, and flavonol content WEML determined HPLC contained 4 flavonols in following order: quercetin‐3‐β‐D‐glucose (QT‐G) > quercetin‐3‐O‐glucose‐6″‐acetate (QT‐GA) rutin (RT) quercetin (QT). In oxygen radical absorbance capacity (ORAC) assay, QT had highest peroxyl radical‐scavenging a similar hydroxyl as...
The entrocytes of the small intestine can only absorb monosaccharides such as glucose and fructose from our diet. intestinal absorption dietary carbohydrates maltose sucrose is carried out by a group a-glucosidases. Inhibition these enzymes significantly decrease postprandial increase blood level after mixed carbohydrate Therefore, inhibitory activity Omija (Schizandra chinensis) extract against rat a-glucosidase porcine pancreatic a-amylase were investigated in vitro vivo. activities water...
Artemisia iwayomogi has been used as a folk medicine for treating various diseases including inflammatory and immune-related diseases. Scopoletin (1) scopolin (2) were isolated from this species. showed more potent peroxyl radical-scavenging capacity, reducing cellular antioxidant capacity compared to (2). The inhibitory effect of 1 on the receptor activator nuclear factor κB ligand-induced osteoclastic differentiation RAW 264.7 macrophage cells was also than that 2. production general...
Abstract: During the heat processing of raw ginseng to produce red ginseng, amino acid derivatives such as arginyl‐fructose (AF) and arginyl‐fructosyl‐glucose (AFG) are formed at high levels, through amadori rearrangement, early step Maillard reaction, from arginine glucose or maltose, respectively. However, very limited information is available about effect structural difference between AF AFG on various biological activities. This first report mode action type 2 diabetes management related...
The functional properties of Korean red ginseng (KRG) are known to be dependent upon the extent heat processing. We demonstrated that repeated processing in preparation KRG decreased its arginyl-fructosyl-glucose (AFG) content and metal chelating capacity. On other hand, total phenolic compound content, vitro peroxyl radical scavenging ability, cellular hydroxyl ability increased with may due content. seems result mainly from Amadori compounds such as arginyl-fructose AFG. protective against...
One new monoterpenoid glycoside, myresculoside (1), and eleven known compounds, were isolated from methanol extract of Myrica esculenta leaves by repeated column chromatography. The effects these compounds on angiotensin I-converting enzyme (ACE) inhibition investigated. Compounds 3 4 showed the most potent ACE with rates 29.97% 25.63% at concentration 100 µM, respectively. 5, 6, 11 weak activity inhibitory 0.07-1.41% µM.