Jung‐Sook Lee

ORCID: 0000-0003-0300-8836
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About
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Research Areas
  • Genomics and Phylogenetic Studies
  • Microbial Community Ecology and Physiology
  • Probiotics and Fermented Foods
  • Bacteriophages and microbial interactions
  • Plant Disease Resistance and Genetics
  • Plant Pathogens and Fungal Diseases
  • Enzyme Production and Characterization
  • Microbial Natural Products and Biosynthesis
  • Molecular Biology Techniques and Applications
  • Aquaculture disease management and microbiota
  • Food Quality and Safety Studies
  • Identification and Quantification in Food
  • Microbial Metabolism and Applications
  • Gut microbiota and health
  • Plant-Microbe Interactions and Immunity
  • Oral microbiology and periodontitis research
  • Protist diversity and phylogeny
  • Biofuel production and bioconversion
  • Ecology and Conservation Studies
  • Cancer Research and Treatments
  • Plant Pathogenic Bacteria Studies
  • Actinomycetales infections and treatment
  • Agriculture, Soil, Plant Science
  • Plant Molecular Biology Research
  • Bacterial Identification and Susceptibility Testing

Korea Research Institute of Bioscience and Biotechnology
2015-2024

Korea University of Science and Technology
2015-2024

Ministry of Science and ICT
2024

Towson University
2018-2024

Sungkyunkwan University
2021-2024

National Institute of Animal Science
2021

Seoul National University
2021

Korea Atomic Energy Research Institute
2021

Pusan National University Hospital
2019-2020

Pusan National University
2019

Abstract Biocontrol offers a promising alternative to synthetic fungicides for the control of variety pre- and post-harvest diseases crops. Black rot, which is caused by pathogenic fungus Ceratocytis fimbriata , most destructive disease sweet potato, but little currently known about potential biocontrol agents this fungus. Here, we isolated several microorganisms from tuberous roots shoots field-grown potato plants, analyzed their ribosomal RNA gene sequences. The belonging genus Pantoea...

10.1038/s41598-019-52804-3 article EN cc-by Scientific Reports 2019-11-08

Abstract Taxonomic and functional research of microorganisms has increasingly relied upon genome-based data methods. As the depository Global Catalogue Microorganisms (GCM) 10K prokaryotic type strain sequencing project, Type Strain (gcType) published 1049 genomes sequenced by GCM project which are preserved in global culture collections with a valid status. Additionally, information provided through gcType includes >12 000 publicly available genome sequences from GenBank incorporated...

10.1093/nar/gkaa957 article EN cc-by Nucleic Acids Research 2020-10-28

Akkermansia muciniphila is a commensal bacterium using mucin as its sole carbon and nitrogen source. A. promising candidate for next-generation probiotics to prevent inflammatory metabolic disorders, including diabetes obesity, increase the response cancer immunotherapy. In this study, comparative pan-genome analysis was conducted investigate genomic diversity evolutionary relationships between complete genomes of 27 strains, KGMB strains isolated from healthy Koreans. The showed that formed...

10.1080/19490976.2021.2025017 article EN cc-by-nc Gut Microbes 2022-03-09

Bacterial cancer therapies aim to manipulate bacteria effectively deploy therapeutic payloads tumors. Attenuated alone often cannot eradicate solid Salmonella can be engineered deliver cytotoxic drugs either trigger an immune response or increase antitumor efficacy when combined with chemotherapeutic drugs. However, the extracellular matrix (ECM) surrounding cells forms a barrier that limits ability of and penetrate eliminate To overcome this limitation, we developed strategy combine...

10.1016/j.jconrel.2023.02.001 article EN cc-by-nc-nd Journal of Controlled Release 2023-02-07

The rapidly increasing prevalence of obesity and overweight, especially in children adolescents, has become a serious societal issue. Although various genetic environmental risk factors for pediatric overweight have been identified, the problem not solved. In this study, we examined whether nanoplastic (NP) pollutants can act as obesogens using mouse models exposed to NPs derived from polystyrene polypropylene, which are abundant environment. We found abnormal weight gain progeny until 6...

10.1016/j.envint.2024.108522 article EN cc-by-nc-nd Environment International 2024-02-20

Two isolates from rhizosphere soil of cotton, designated Gh-67(T) and Gh-48(T), which produced large amounts extracellular polysaccharide possessed plant-growth-promoting traits, were characterized phenotypically genotypically. The strains Gram-negative cells non-motile rods that grew optimally at 28°C between pH 4 7. 16S rRNA gene sequence analysis Gh-48(T) placed them in the genus Mucilaginibacter, with pairwise similarity type related genera ranging 93.9 to 98.2 %. major fatty acids...

10.1099/ijs.0.018713-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2009-11-28

Three novel bacterial strains, designated Vu-144(T), Vu-7 and Vu-35, were isolated on minimal medium from rhizosphere soil of field-grown cowpea subjected to a taxonomic study using polyphasic approach. Cells the strains Gram-stain-negative, non-motile, non-spore-forming, coccoid rods, formed non-pigmented colonies. Phylogenetic analysis based 16S rRNA gene sequences revealed that strain Vu-144(T) was affiliated with an uncultivated lineage phylum Bacteroidetes. Its closest phylogenetic...

10.1099/ijs.0.069377-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2014-11-18

Although susceptibility to seed shattering causes severe yield loss during cereal crop harvest, it is an adaptive trait for dispersal in wild plants. We previously identified a recessive locus, sh-h, from the rice mutant line Hsh that carries enhanced abscission layer. Here, we further mapped sh-h 34-kb region on chromosome 7 by analyzing 240 F(2) plants and five F(3) lines cross between Blue&Gundil. had point mutation at 3' splice site of seventh intron within LOC_Os07g10690, causing 15-bp...

10.1111/j.1365-313x.2009.04039.x article EN The Plant Journal 2009-10-06

A Gram-positive and catalase-negative coccus that formed chains, designated strain FP48-3T, isolated from fermented sausage ('mum'), was studied systematically. Strain FP48-3T facultatively anaerobic produced l-lactic acid glucose. Straight-chain fatty acids C18 : 1 C16 0 were the dominant components. The DNA G+C content of 37.9 mol%. On basis 16S rRNA RNA polymerase α-subunit (rpoA) gene sequence analysis, closely related to Enterococcus hirae LMG 6399T, durans 10746T faecium 11423T, with...

10.1099/ijs.0.65535-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2008-07-01

A taxonomic study was carried out on two strains that came from kimchi, a traditional Korean fermented-vegetable food. The DNA G+C content of these 37 mol %. Both contained Lys-Ala-Ser in the cell walls. On basis morphological, physiological and chemotaxonomic characteristics, together with data 16S rDNA sequence comparisons DNA-DNA reassociation, it is proposed represent novel species genus Weissella, Weissella koreensis sp. nov. type strain S-5623T (= KCTC 3621T KCCM 41516T = JCM 11263T).

10.1099/00207713-52-4-1257 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2002-07-01

By 16S rDNA sequence analysis, two strains identified previously as members of the genus Nocardioides, namely 'Nocardioides fulvus' IFO 14399 and Nocardioides sp. ATCC 39419, were found to form lines descent distinct from Nocardioides. Therefore, studied taxonomically in detail by phenotypic, particularly chemotaxonomic, characterization, phylogenetic analysis including other related taxa. The genomic DNA G+C contents 'N. 39419 are 70 68 mol%, respectively. contain ll-diaminopimelic acid...

10.1099/00207713-49-2-743 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 1999-04-01

Although many genomic alterations have been observed in lung cancer, their clinicopathologic significance has not thoroughly investigated. This study screened the aberrations across whole genome of non-small cell cancer cells with high-resolution and investigated implications.One-megabase resolution array comparative hybridization was applied to 29 squamous carcinomas 21 adenocarcinomas lung. Tumor normal tissues were microdissected extracted DNA used directly for without amplification. The...

10.1158/1078-0432.ccr-05-1157 article EN Clinical Cancer Research 2005-12-01

Leuconostoc citreum is one of the most prevalent lactic acid bacteria during manufacturing process kimchi, best-known Korean traditional dish. We have determined complete genome sequence L. KM20. It consists a 1.80-Mb chromosome and four circular plasmids reveals genes likely involved in kimchi fermentation its probiotic effects.

10.1128/jb.01862-07 article EN Journal of Bacteriology 2008-02-16

The taxonomic position of a Gram-positive coccus, designated strain CAU 28T, isolated from activated sludge foam was determined by using polyphasic approach. Based on its cellular morphology and the results biochemical tests, 28T identified tentatively as member genus Lactococcus. Comparative 16S rRNA gene sequence analysis showed that levels similarity between type strains recognized Lactococcus species ranged 90.4 to 97.2 %. DNA–DNA hybridization studies displayed less than 26.1 %...

10.1099/ijs.0.65527-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2008-08-01

Microbacterium strain AI-S262(T) was isolated from the rhizoplane of neem seedlings in Botanical garden Tamilnadu Agricultural University, Coimbatore, India, and subjected to phenotypic, chemotaxonomic genetic characterization. Cells this were Gram-stain-positive, motile, non-spore-forming, short rods formed light-yellow-pigmented colonies on nutrient agar. Strain contained MK-12 MK-13 as main respiratory quinones, anteiso-C(15 : 0), anteiso-C(17 0) iso-C(16 predominant fatty acids,...

10.1099/ijs.0.015800-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2009-11-03

A methylotrophic nitrogen-fixing bacterial strain, Ah-143 T , isolated from the rhizosphere soil of field-grown groundnut was analysed by a polyphasic taxonomic approach. Comparative 16S rRNA gene sequence analysis combined with rpoB allocated strain to family Enterobacteriaceae Enterobacter radicincitans and cowanii as closest relatives. The is Gram-stain-negative, non-spore-forming, aerobic motile, having straight rod-shaped cells DNA G + C content approximately 53.2 mol%. utilizes...

10.1099/ijs.0.013664-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2009-11-03

Two Gram-stain-negative, non-motile, non-spore-forming, rod-shaped bacterial strains, designated 3B-2 T and 10AO , were isolated from a sand sample collected the west coast of Korean peninsula by using low-nutrient media, their taxonomic positions investigated in polyphasic study. The strains did not grow on marine agar. They grew optimally at 30 °C pH 6.5–7.5. Strains shared 97.5 % 16S rRNA gene sequence similarity mean level DNA–DNA relatedness 12 %. In phylogenetic trees based sequences,...

10.1099/ijs.0.025874-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2010-05-29

A pink, aerobic, facultatively methylotrophic, motile, Gram-negative rod, designated Gh-105(T), was isolated from the phyllosphere of cotton Coimbatore (Tamilnadu, India). 16S rRNA gene sequence analysis showed clearly that isolate belonged to Methylobacterium cluster. Strain Gh-105(T) most closely related adhaesivum AR27(T) (99% similarity) and iners 5317S-33(T) (97.5%). The grew with C(1) compounds such as methanol dichloromethane, but not formaldehyde, formate, methylamine, trimethylamine...

10.1099/ijs.0.030148-0 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2011-03-05

Genomic information is essential for taxonomic, phylogenetic, and functional studies to comprehensively decipher the characteristics of microorganisms, explore microbiomes through metagenomics, answer fundamental questions nature human life. However, large gaps remain in available genomic sequencing published bacterial archaeal species, are even larger fungal type strains. The Global Catalogue Microorganisms (GCM) leads an internationally coordinated effort sequence strains close maps...

10.1093/gigascience/giy026 article EN cc-by GigaScience 2018-03-22

Salterns, one of the most extreme natural hypersaline environments, are a rich source halophilic and halotolerant microorganisms, but they remain largely underexplored ecological niches in discovery bioactive secondary metabolites. In continued efforts to investigate metabolic potential microbial populations from chemically sites, three new lipopeptides named iturin F1, F2 A9 (1–3), along with A8 (4), were isolated Bacillus sp. KCB14S006 derived saltern. The structures compounds established...

10.3390/md14040072 article EN cc-by Marine Drugs 2016-04-02

Abstract The rhizosphere microbial community is closely associated with plant disease by regulating growth, agricultural production, nutrient availability, hormone and adaptation to environmental changes. Therefore, it very important identify the microbes around roots understand their functions. While studying differences between microbiota of healthy diseased apple trees find cause tree disease, we isolated a novel strain, designated as B3-10 T , from soil tree. genome relatedness indices...

10.1038/s41598-024-51492-y article EN cc-by Scientific Reports 2024-01-10
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