A5090573083- Lymphoma Diagnosis and Treatment
- Multiple Myeloma Research and Treatments
- Acute Myeloid Leukemia Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Chronic Myeloid Leukemia Treatments
- Chronic Lymphocytic Leukemia Research
- COVID-19 Clinical Research Studies
- Hemoglobinopathies and Related Disorders
- Platelet Disorders and Treatments
- CNS Lymphoma Diagnosis and Treatment
- Hematological disorders and diagnostics
- Blood disorders and treatments
- Blood groups and transfusion
- Iron Metabolism and Disorders
- SARS-CoV-2 and COVID-19 Research
- Complement system in diseases
- Immunodeficiency and Autoimmune Disorders
- Eosinophilic Disorders and Syndromes
- COVID-19 Impact on Reproduction
- Inflammatory Biomarkers in Disease Prognosis
- Cancer Treatment and Pharmacology
- Bone and Joint Diseases
- Protein Degradation and Inhibitors
- Immunotherapy and Immune Responses
- Renal and Vascular Pathologies
Sağlık Bilimleri Üniversitesi
2020-2025
Ağrı İbrahim Çeçen University
2023-2025
Eskişehir City Hospital
2025
İstanbul Başakşehir Çam ve Sakura Şehir Hastanesi
2024
University of Health Sciences Antigua
2020-2024
University of Health Sciences
2020-2023
İstanbul Eğitim ve Araştırma Hastanesi
2023
University of Health Science
2022-2023
Fatih University Medical Faculty Hospital
2023
Education Training And Research
2022
The aim of the present study was to examine relationship between anemia and basic instrumental activities daily living in older male patients.
This research sought to investigate the possible connection between anemia and various parameters of comprehensive geriatric assessment in elderly individuals diagnosed with Dementia Lewy Bodies (DLB). To our knowledge, this investigation represents first attempt examine how impacts patients suffering from DLB. cross-sectional study encompassed 147 DLB a single outpatient clinic. The defined as hemoglobin levels under 12 g/dL for women 13 men. Patients' demographic information, coexisting...
Serin, Istemi, Ahmet Unal, Arzu Dobral, Fatma Elif Eroglu, Erdem Ayik, Jale Oz Mehmet Barış Cengiz, Okan Kati, Toros Taskin, Vural Bastug, and Abdulkadir Karismaz. The effect of altitude on polycythemia vera: Is it necessary to change limits? High Alt Med Biol. 00:00-00, 2025. Background: Polycythemia vera (PV) is a myeloproliferative disease characterized by high hemoglobin/hematocrit levels accompanied JAK2 mutations. In this study, we aimed establish new hemoglobin cut-off value for the...
COVID-19 (Coronavirus Disease-2019) is a pandemic disease, infecting more than 26.5 million people. Since there no specific and effective treatment; early diagnosis optimal isolation of the patient are vital importance. Real-time polymerase chain reaction-based (RT-PCR) analyses do not achieve sufficient sensitivity in disease. The data from 2217 patients diagnosed as between March 2020 June hospitalized or discharged with home were retrospectively analyzed. Demographic data, comorbidities,...
Abstract Background Aspergillus species meet the most important group of invasive fungal diseases (IFD) in immunosuppressed patients. Galactomannan is a polysaccharide antigen located wall structure Aspergillus. The commonly used method for detection enzyme‐linked immunoassay (ELISA). galactomannan lateral flow assay (LFA) constitutes one new methods diagnosis aspergillosis (IA). goal this study was to demonstrate efficacy LFA our patients and compare it synchronous ELISA results. Methods...
Severe inflammation and one or more extrapulmonary organ dysfunctions have been reported this clinical picture is defined as "multisystem inflammatory syndrome in adults" (MIS-A) severe coronavirus disease-2019 (COVID-19). We aimed to determine the effect of LDH/lymphocyte ratio (LLR) on development MIS-A.The data 2333 patients were retrospectively analyzed.MIS-A rate was found be 9.9% MIS-A related mortality 35.3%. LRR level above 0.24 predict with 70% sensitivity 65.2% specificity. The...
Background and aimLeptin is mainly produced in adipose tissue released into systemic circulation. Leptin its receptor LEPR activate the Janus kinase/signal transducers activators of transcription signaling cascade increase cytokine discharge. In our study, we aimed to examine role leptin gene (LEP) rs7799039 rs1137101 polymorphisms on susceptibility for febrile neutropenia (FEN) attacks their relationship with clinical findings during course FEN.MethodsThis study included pediatric patients...
For COVID-19 (Coronavirus Disease-2019) cases, detecting host-based factors that predispose to infection is a very important research area. In this study, the aim investigate MBL2 and NOS3 gene polymorphisms in patients with lung involvement, whose first nasopharyngeal PCR results were negative. Seventy-nine diagnosed between April-June 2020 who admitted university hospital, 100 healthy controls included. statistical analysis performed PCR-positive, CT-negative PCR-negative, CT-positive...
Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes syndrome (POEMS) is a rare paraneoplastic of an underlying plasma cell disorder (PCD).1 Castleman disease (CD), itself, can also cause symptoms or signs polyneuropathy, volume overload, cytokine release, but only those with peripheral neuropathy clone be classified as classical POEMS.1 Both POEMS CD variant (CD-POEMS),2 literature lacks standardized treatment approach. Here, we present case who diagnosed...
A multicenter, retrospective, observational study was conducted to explore effectiveness and safety of ixazomib plus lenalidomide with dexamethasone (IRd) in relapsed/refractory multiple myeloma (RRMM) patients following at least ≥ two lines therapy. Patients' treatment responses, overall response rate, progression-free survival adverse events were recorded. Mean age 54 66.5 ± 9.1 years. There 20 (37.0%) progression. Median 13 months who received a median three therapy 7.5-month follow-up...
Oxidative stress (OS), which leads to DNA damage, plays a role in the pathogenesis of Coronavirus disease 2019 (COVID-19). We aimed evaluate repair gene variants [X-ray cross complementing 4 (XRCC4) rs28360071, rs6869366, and X-ray cross-complementary 1 (XRCC1) rs25487] susceptibility COVID-19 Turkish population. also evaluated its effect on clinical course disease. A total 300 subjects, including 200 patients 100 healthy controls, were included this study. These genotyped using polymerase...
Recent studies have shown the increased risk of mortality in cases with acute leukemia and iron overload. We aimed to determine status overload patients leukemia.Patients diagnosed lymphoblastic (ALL) myeloid (AML) between January 2015 December 2019 were included study.At 6 months, there statistically more serum ferritin >1000 AML group compared ALL (p = 0,011).Iron occurs earlier AML; difference disappears after months treatment. It is correct point emphasize that an important factor...
Invasive pulmonary aspergillosis (IPA) is seen during coronavirus-2019 (COVID-19), has been reported in different incidences, and defined as COVID-19-associated (CAPA). Detection of galactomannan antigen an important diagnostic step diagnosing IPA. Enzyme-linked immunoassay (ELISA) the most frequently used method, lateral flow assay (LFA) increasingly with high sensitivity specificity for rapid diagnosis. The present study aimed to compare LFA ELISA diagnosis CAPA COVID-19 patients followed...
Chronic lymphocytic leukemia (CLL) is a B-lymphoproliferative disease with varying clinical characteristics, which occurs mostly in older ages. In studies from literature, we see that different parameters are examined to determine the prognosis of CLL. The main purpose our study relationship lymphocyte/monocyte ratio (LMR) value CLL, has been previously shown be prognostic factor various solid organ tumors and some hematological malignancies.A total 173 patients who were followed up between...
BackgroundThe suppressor of cytokine signaling-1 (SOCS-1) functions to induce an appropriate immune response and is essential physiological regulator interferon signaling.DNA methylation involves adding a methyl group the carbon 5 position cytosine.Besides comparing SOCS-1 gene status between patients with multiple myeloma (MM) healthy controls, this study also aimed demonstrate effect distribution on progression-free survival (PFS) overall (OS). MethodsThis included 120 diagnosed MM January...
ABSTRACT Circadian Clock Protein PERIOD 3 ( PER-3 ) is situated on chromosome 1p36.23 and has a polymorphic domain that expresses 4 or 5 copies of the 54-bp tandem repeat sequence. gene polymorphisms play role in dysregulation immune system. This study intended to investigate distributions clinical effectiveness polymorphism multiple myeloma (MM) patients. One hundred fifty patients diagnosed between January 2007-2009 100 healthy individuals were included this study. All suitable for...