A5114123706- CO2 Sequestration and Geologic Interactions
- Methane Hydrates and Related Phenomena
- Palliative Care and End-of-Life Issues
- Geological Modeling and Analysis
- Cancer Treatment and Pharmacology
- SARS-CoV-2 and COVID-19 Research
- Dermatological and COVID-19 studies
- Patient Dignity and Privacy
- Medical Research and Treatments
- Management of metastatic bone disease
- Chemotherapy-induced organ toxicity mitigation
- Autoimmune and Inflammatory Disorders Research
- Hydrology and Watershed Management Studies
- Lung Cancer Research Studies
- Breast Cancer Treatment Studies
- Ocean Acidification Effects and Responses
- Flood Risk Assessment and Management
- Climate variability and models
- Ovarian cancer diagnosis and treatment
- Intraperitoneal and Appendiceal Malignancies
- Ethics and Legal Issues in Pediatric Healthcare
- Colorectal Cancer Treatments and Studies
- Osteoarthritis Treatment and Mechanisms
- Diverse Approaches in Healthcare and Education Studies
- Reservoir Engineering and Simulation Methods
Seoul National University Hospital
2006-2024
Seoul National University
2006-2014
We evaluated the pharmacokinetics, tissue concentrations, and toxicities of belotecan during rotational intraperitoneal pressurized aerosol chemotherapy (RIPAC) in pigs. sprayed 10% 30% doses for intravenous six pigs (cohort 1, n=3, 0.50 mg/m²; cohort 2, 1.5 mg/m²). time-dependent plasma concentrations before RIPAC to 120 hours twelve peritoneal regions, hepatic renal functions 2 cohorts. Mean values peak concentration (Cmax), time Cmax, taken Cmax drop half, area under curve from zero last...
6103 Background: The objective of this study were to observe the markers aggressive care in cancer patients including appropriateness chemotherapy and evaluate trends cancer-care assess their association with availability related health resources. Methods: We designed restrospective cohort composed who diagnosed as metastatic received palliative at Seoul National University Hospital 2002. Hematologic malignancy hepatocellular carcinoma local treatment alone excluded. Two hundreds ninety...
670 Background: Bcl-2 is an anti-apoptotic marker and regulated by hormonal receptor pathways in breast cancer. We performed this study to assess the prognostic significance of ER, PR, p53, c-erbB2, bcl-2, Ki-67, EGFR as a for relapse cancer patients who received same adjuvant therapy single institution. Methods: A cohort 154 curatively resected had 4 lymph nodes or more doxorubicin cyclophosphamide followed paclitaxel (AC/T) chemotherapy was analyzed clinicopathologic characteristics...
e19554 Background: Even though patient self-determination is encouraged, clinical decisions involving cancer patients are often made by surrogates, but sometimes their judgment conflicts with the will of patient. The goal this study was to evaluate pattern such proxy and investigate scenarios surrogate consent. Methods: A single-center, retrospective patients, who expired between Jan 1, 2009 Dec 31, conducted at Seoul National University Hospital, Seoul, Korea. Informed consents (N= 8,639)...
이 논문은 연명의료결정제도에서 미성년자의 연명의료 결정에 대해 문제점을 찾고 그 개선방안을 마련하는 데 목적을 두고 있다. 2018년 2월 4일부터 시행되고 있는 연명의료결정제도에 따라 원하지 않는 연명의료에 거부가 가능하게 되면서, 우리 사회에서 생애 말기 자기결정권 보장이 확립되고 연명의료결정법 제10조제3항에 환자가 미성년자인 경우 환자 및 법정대리인에게 확인을 받은 후 연명의료계획서를 작성할 수 연명의료결정법에 따른 미성년자는 아동복지법에 18세까지 아동을 의미하므로, 연명의료계획서 작성 시 적용을 받는 연령대는 0세부터 범위가 매우 넓다. 연명의료결정법에서는 기준을 의사결정 능력이 아닌 연령대에 일괄적으로 적용하고 있어, 자칫 거부를 결정하는 자기결정권이 법정대리인의 동의권을 더욱 강조하여 보장하게 되는 상황이 발생할 그러므로 본 고에서는 자기결정권과 관련하여 여러 국가의 법제화 사례를 살펴보고, 법정대리인으로서 부모의 동의권 보장과 최선의 이익 간의 균형을 맞출...
e20630 Background: Although various prognostic factors have been proposed to predict survival in terminally ill cancer patients, accurate prognostication is still a challenging task for oncologists. The objective of this study was evaluate whether the time interval between diagnosis advanced and cessation active anti-cancer treatment (ATP; period) can patients. Methods: We prospectively evaluated 79 patients with (recurrent or metastatic) who were determined as terminal stage, namely...
<h3>Background</h3> In our previous study, we have conducted a case-control study to demonstrate the mitochondrial DNA (mtDNA) haplogroups in development of knee osteoarthritis (OA). However, there were no mtDNA associated with OA. <h3>Objectives</h3> The objective this was elucidate role OA prospective on-going community-based cohort. <h3>Methods</h3> This cohort established 2001 investigate epidemiologic characteristics major chronic diseases Korea by Korean Genome and Epidemiology Study,...