A5058933826- Health and Lifestyle Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Lipoproteins and Cardiovascular Health
- Adipokines, Inflammation, and Metabolic Diseases
- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Obesity, Physical Activity, Diet
- Diabetes Management and Research
- Cardiovascular Disease and Adiposity
- Diabetes and associated disorders
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Aging, Health, and Disability
- Regulation of Appetite and Obesity
- Blood Pressure and Hypertension Studies
- Pancreatic function and diabetes
- Metabolism, Diabetes, and Cancer
- Pharmacology and Obesity Treatment
- Liver Disease Diagnosis and Treatment
- Global Public Health Policies and Epidemiology
- Advanced X-ray and CT Imaging
- Hormonal Regulation and Hypertension
- COVID-19 Clinical Research Studies
- Eicosanoids and Hypertension Pharmacology
- Veterinary Equine Medical Research
Universidad Simón Bolívar
2017-2025
University of Zulia
2014-2024
Simón Bolívar University
2017-2024
Universidad Católica de Cuenca
2014-2022
Baylor University
2020
Universidad Andrés Bello
2018
Central University of Venezuela
2001-2013
Centro de Investigaciones Cardiovasculares
2012
Metabolic Diseases Research Center
2010
Hospital Universitario de Maracaibo
2008
Photoaging (PA) is considered a silent disease affecting millions of people globally and defined as skin damage due to prolonged exposure ultraviolet radiation (UVR) from the sun. Physiologically, in state renewal synthesis components extracellular matrix (ECM). However, UVR affects production ECM, functioning response cells begins change, thus expressing clinical phenotypic characteristics PA. The primary mechanisms involved PA are direct DNA cells, increases oxidative stress, activation...
Chimeric antigen receptor T cell (CAR cell) therapy has emerged as a prominent adoptive and therapeutic approach of great interest in the fight against cancer. This shown notorious efficacy refractory hematological neoplasm, which bolstered its exploration field solid cancers. However, successfully managing tumors presents considerable intrinsic challenges, include necessity guiding modified cells toward tumoral region, assuring their penetration survival adverse microenvironments,...
Objective: To investigate the effect of bread formulated with 6 g β-glucan (oat soluble fiber) on serum lipids in overweight normotensive subjects mild to moderate hypercholesterolemia. Design: Thirty-eight male [mean age 59.8 ± 0.6 yr, mean body mass index (BMI) 28.3 kg/m2] who were eligible for study ate an isocaloric diet a 1-week period. They then divided into 2 groups: group A (n = 19), maintained American Heart Association (AHA) Step II diet, including whole wheat bread, and B AHA...
Background and Aim . Insulin resistance (IR) is a prominent pathophysiologic component in myriad of metabolic disorders, including obesity, prediabetes, type 2 diabetes mellitus, which are common our locality. The objective this study was to determine the prevalence IR factors associated with condition an adult population from Maracaibo city, Venezuela. Methodology A cross-sectional, descriptive multistaged randomized sampling carried out 2026 adults. defined as HOMA2-IR ≥ 2. multiple...
During pregnancy, women undergo several metabolic changes to guarantee an adequate supply of glucose the foetus. These modifications develop what is known as physiological insulin resistance. When this process altered, however, gestational diabetes mellitus (GDM) occurs. GDM a multifactorial disease, and genetic environmental factors play crucial role in its aetiopathogenesis. has been linked both macroscopic molecular alterations placental tissues that affect physiology. This review...
To assess the presence of Helicobacter DNA in gastric mucosa Thoroughbred horses.Squamous and glandular samples were collected from 20 Thoroughbreds. None these horses had shown any clinical symptoms gastrointestinal disease. Necropsy tissues analysed using histopathological techniques a genus-specific PCR assay followed by sequencing amplicons. Seven diagnosed with ulceration, five gastritis six both pathologies. Only two healthy mucosa. Helicobacter-like was detected out seven ulcers,...
Type 2 diabetes mellitus and obesity are the most frequent endocrine-metabolic diseases in world their pathogenic basis characterized by insulin resistance secretion defects that can be demonstrated through several alterations carbohydrates, lipids, protein metabolism. The peroxisome proliferator-activated receptors have been identified as key regulators of glucose lipid metabolism, because they act transcription factors stimulate synthesis a wide variety processes (energetic proliferation,...