A5072378786- Malaria Research and Control
- Mosquito-borne diseases and control
- Computational Drug Discovery Methods
- Receptor Mechanisms and Signaling
- Neuroscience and Neuropharmacology Research
- Photoreceptor and optogenetics research
- Renin-Angiotensin System Studies
- Viral Infections and Outbreaks Research
- Complement system in diseases
- SARS-CoV-2 and COVID-19 Research
- Invertebrate Immune Response Mechanisms
- Vector-borne infectious diseases
- Travel-related health issues
- Viral Infections and Vectors
- COVID-19 Clinical Research Studies
- Drug Transport and Resistance Mechanisms
- Dengue and Mosquito Control Research
- HIV Research and Treatment
- COVID-19 epidemiological studies
- Blood Pressure and Hypertension Studies
- Helminth infection and control
- Mitochondrial Function and Pathology
- Health and Well-being Studies
- Statistical Methods and Bayesian Inference
- Parasitic Infections and Diagnostics
National Institute of Malaria Research
2017-2025
Academy of Scientific and Innovative Research
2023-2025
Indian Council of Medical Research
2018-2023
Oregon Health & Science University
2009-2016
Wellcome Centre for Molecular Parasitology
2014
Wellcome Trust
2014
University of Glasgow
2010-2014
Ruxmaniben Deepchand Gardi Medical College
2008
Introduction This highly contagious zoonotic corona virus (SARS-CoV-2) spread to most parts of the world (200 countries) and created a public health emergency. Due its novel nature indistinctness, different sources information suggestions were developed guide individuals about transmission prevent infection. Responses active intervention efforts have posed some relevant questions on population understanding attitudes toward COVID-19. The present study is aims assess COVID-19 related...
To study the epidemiology of dengue with reference to serological, demographic profile, spatio-temporal distribution, vectors, circulating serotypes and coinfections.Demographic data presenting symptoms fever cases reporting clinic were recorded. Suspected patients tested for dengue, chikungunya malaria. Dengue specific RT-PCR was performed detect DENV serotypes. Vector surveys carried out Aedes breeding.Of 5536 during 2012 2015, 1536 (27.7%) had confirmed dengue. The peak in positivity...
Malaria remains a global health problem despite availability of effective tools. For malaria elimination, drugs targeting sexual stages Plasmodium falciparum need to be incorporated in treatment regimen along with schizonticidal interrupt transmission. Primaquine is recommended as transmission blocking drug for its effect on mature gametocytes but not extensively utilized because associated safety concerns among glucose-6-phosphate dehydrogenase (G6PD) deficient patients. In present work,...
Abstract Background India is committed to malaria elimination by the year 2030. According classification of endemicity, National Capital Territory Delhi falls under category 1, with an annual parasite incidence <1, and was targeted for 2022. Among others, population movement across states one key challenges control, as it can result in imported malaria, thus introducing local transmission area nearing elimination. Objective This descriptive study attempts assess contribution such...
Purpose The purpose of this paper is to assess the present level knowledge about disaster preparedness and mitigation among undergraduate medical students. Rarely a week goes by when major not reported in media – that results death destruction. There general reluctance people accept tragedy can appear any time form disaster. Unfortunately, disasters are seen more context emergency responses than pre‐planning or measures. Continuous saves lives, lessens personal suffering loss reduces...
Dengue is specially owing to inadequate water supply and poor solid waste management , which are favorable for multiplication of the main vectors including Aedes ageypti coupled with lack proven anti viral therapy no efficient vaccine .there many cases both dengue shock syndrome haemmorhagic fever making it a major public health burden sending ominous signal resulting rising morbidity & mortality, deleterious effect on DALY [disability adjusted life year] QALY [quality though affect all...
Various studies have implicated the concave surface of arrestin in binding cytosolic rhodopsin. However, specific sites contact between two proteins not previously been defined detail. Here, we report that shares part same site on rhodopsin as does transducin Gα subunit C-terminal tail, suggesting both to may share some similar underlying mechanisms. We also identify areas near this region. Both lie N-domain, one so-called "finger" loop (residues 67-79) and other 160 155-165). mapped these...
Efforts for malaria elimination in India focus solely on the more prevalent human parasites of
Plasmodium falciparum is usually asynchronous during in vitro culture. Although various synchronization methods are available, they not able to narrow the range of ages parasites. A newly developed method described that allows parasites produce cultures with an age as low 30 minutes. Trophozoites and schizonts enriched using Plasmion. The late stage immobilized a monolayer onto plastic Petri dishes concanavalin A. Uninfected erythrocytes placed for limited time period, which on rupture...
: India is on track to eliminate malaria by 2030 but emerging resistance the first-line antimalarials a recognized threat. Two instances of rapid development, spread, and natural selection drug-resistant mutant parasites (chloroquine in entire Artesunate+Sulfadoxine-Pyrimethamine (AS+SP) India's north-eastern states) translated into drug policy changes for P. falciparum 2010 2013, respectively. Looking at these SP resistance-conferring mutation profile falciparum, it becomes evident...
Malaria elimination mandates early and accurate diagnosis of infection. Although malaria is programmatically dependent on microscopy/RDTs, molecular has much better diagnostic accuracy. Higher cost diagnoses a recognized challenge for use at the point care. Because funding always constraint, we performed financial cost-analyses available platforms utilization budget.