- Hepatitis B Virus Studies
- Hepatitis C virus research
- Monoclonal and Polyclonal Antibodies Research
- HIV Research and Treatment
- Phase Equilibria and Thermodynamics
- Hepatitis Viruses Studies and Epidemiology
- HIV, TB, and STIs Epidemiology
- Chemical Thermodynamics and Molecular Structure
- Thermodynamic properties of mixtures
- Liver Disease Diagnosis and Treatment
- Protein purification and stability
- Vector-borne infectious diseases
- Viral Infections and Immunology Research
- Bacteriophages and microbial interactions
- Reproductive tract infections research
- HIV, Drug Use, Sexual Risk
- Viral gastroenteritis research and epidemiology
- Herpesvirus Infections and Treatments
- Syphilis Diagnosis and Treatment
- Influenza Virus Research Studies
- Mosquito-borne diseases and control
- Ionic liquids properties and applications
- Cervical Cancer and HPV Research
- Plant-based Medicinal Research
- Bartonella species infections research
CS Diagnostics
2015
BASF (Germany)
2012
University of Kaiserslautern
2004-2011
Nizhny Novgorod Research Institute of Traumatology and Orthopedics
2002
Centers for Disease Control and Prevention
2002
An assay to measure avidity index (AI) was developed diagnose incident hepatitis C virus (HCV) infections. The demonstrated an AI value statistically significantly lower in primary HCV infections than chronic When the applied past resolved infections, difference values not as significant between and Lower obtained may be directly related levels of immunoglobulin G anti-HCV either new or
The purpose of the present study was to develop enzyme immunoassay (EIA) for detection IgG anti-hepatitis E virus (HEV) activity using two new recombinant proteins as antigenic targets, and evaluate these EIA with aid statistical methods.Two proteins, a mosaic protein pB166 containing region 452-617 aa ORF2 HEV Burma strain, were used EIA. This evaluated several panels serum specimens obtained from: (i) acutely HEV-infected patients; (ii) patients non-A, non-C hepatitis; (iii) normal blood...
This article reexamines some opinions concerning pH requirements for optimal immobilization of monoclonal antibodies (mAbs) by passive adsorption in antigen capture ELISA. It was discovered that substitution "classical" sodium phosphate (pH 7.5) and carbonate 9.5) coating solutions acid 2.8) buffers maximized 4 out 10 different tested anti-HBsAg mAbs, resulting a 1.5-2.5 increase binding curve coefficients. By measuring both mAbs amounts functionality, the enhancement effect attributed to...
An artificial antigen composed of 12 small antigenic regions derived from the ORF2 and ORF3 HEV proteins was designed. The gene encoding for this assembled synthetic oligonucleotides by a new method called Restriction Enzyme-Assisted Ligation (REAL). diagnostic relevance second generation mosaic protein (HEV MA-II) demonstrated testing against panel 142 well defined anti-HEV positive negative serum samples. data obtained in study support substantial potential antigen.
The high-pressure phase equilibrium of two ternary systems—(ethene + water acetone) and (ethane acetone)—was investigated by a static−analytical method. Both systems exhibit the “salting-out” phenomenon upon pressurization gaseous compound. composition coexisting liquid phases L1 L2 liquid−liquid−vapor (L1L2V) was determined at (293, 313, 333) K over entire pressure range that spans from about (2.9 to 8.0) MPa for (ethene (2.3 5.8) acetone), respectively. Additionally, coordinates both...
Errors in forecasting the expected number of HIV patients lead to organizational and economic problems. In particular, budgetary funding purchases drugs diagnostic means may turn out be inadequate a real epidemiological situation. Study objective: To ascertain accuracy modeling infection based on standard data supplemented with incidence early cases. The expediency this task is determined by necessity find approaches making more accurate prognoses. Materials methods: Retrospective dynamics...
The epidemiological situation for HIV infection in Russia remains to be extremely stringent, which requires a search new, more efficient and cost-effective solutions aimed at countering the epidemic. inclusion of laboratory studies with use test system determination remoteness routine surveillance practices will permit determine frequency occurrence early cases infections among newly diagnosed HIV-positive persons. analysis this criterion population level help objectively evaluate...
At temperatures from (289 to 353) K, the ternary system (ethene + water 2-propanol) is known exhibit a region of liquid−liquid−vapor (L1L2V) equilibria at elevated pressures that bordered by lower ((L1 = L2)V) and upper (L1(L2 V)) critical end point lines. This particular demixing effect commonly as "salting out supercritical gas". In this work, adding different electrolytes on pressure both points (293 333) K investigated.
Adding some salt to a homogeneous aqueous liquid solution of an organic solvent often results in liquid–liquid phase split. However, such split can also be achieved by charging with gas, particular when the temperature is close critical that specific gas. This phenomenon called "salting out near-critical gas". It might applied high-pressure extraction process, for example, separate and recover valuable biomolecules from phases. Using neutral gas like, ethene pressurizing additionally allows...
1 0 | n u m . 3 antitumor eFFiCaCY oF liPosomal doxoruBiCin HYdroCHloride in ComBination witH tamoxiFen.exPerimental studY a b s t r C -In this paper we evaluated the effectiveness of adjuvant chemotherapy animals (n=30), which created model cancerogenesis.We equal studies: st group control (n=10) -animals were monitored without treatment; 2 nd received therapy with combination drugs: liposomal doxorubicin hydrochloride+tamoxifen;the rd hydrochloride (non-liposomal)+tamoxifen. All for total...
Abstract Untersuchungen zur gasinduzierten Phasentrennung bzw. zum Aussalzen mit nahekritischen Gasen wurden an verschiedenen wässrigen Lösungen (auch ionischem Fluid) durchgeführt. Ziel war der Nachweis und die Charakterisierung von Hochdruckmehrphasengleichgewichten, sich für eine technische Anwendung eignen. Kriterien hierfür sind Auftreten des Flüssig/flüssig‐Phasenzerfalls bei relativ niedrigem Druck, seine Existenz über einen weiten Druck‐ Zusammensetzungsbereich damit verbunden...