- Cardiovascular Function and Risk Factors
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Connexins and lens biology
- Peroxisome Proliferator-Activated Receptors
- Congenital heart defects research
- Mitochondrial Function and Pathology
- Lipoproteins and Cardiovascular Health
- Metabolism, Diabetes, and Cancer
- Nanoparticles: synthesis and applications
- Environmental remediation with nanomaterials
- Radiopharmaceutical Chemistry and Applications
- Cancer, Hypoxia, and Metabolism
- S100 Proteins and Annexins
- Graphene and Nanomaterials Applications
Sun Yat-sen University
2023-2025
Zhaoqing University
2020
BACKGROUND: Individuals with diabetes are susceptible to cardiac dysfunction and heart failure, potentially resulting in mortality. Metabolic disorders frequently occur patients diabetes, usually leads remodeling of structure dysfunction. However, the contribution underlying mechanisms metabolic structural coupling diabetic remain elusive. METHODS: Two mouse models type 2 (T2DM) were used assess alterations glucose/lipid metabolism structure. The potential metabolic-structural molecule ACBP...
Abstract The aim of this study was to evaluate the use nitric acid treatment activatd carbon, and observe whether it can increase amount silver adsorption. We used vacuum condition investigate if we could synthesize higher loading nanoparticles. Furthermore, explored a zero-waste manufacture process tested its antibacterial activity.
Objective: This study aims to describe the expression profile and role of cardiac pigment epithelium-derived factor (PEDF) during development.
Objective: This study describes the expression profiles and roles of cardiac pigment epithelium-derived factor (PEDF) during development. Methods: Gene datasets from Expression Omnibus (GEO) database were used to analyze correlation between PEDF heart disease. Western blotting, immunohistochemistry, histological staining echocardiography assess patterns functions Results: Analysis GEO data sets indicated that correlated with occurrence development various diseases. blotting tissues in mice...
Abstract Under diabetes conditions, sterol regulatory element-binding protein 1 (SREBP1) activation could cause lipid dysfunction, leading to cardiac lipotoxicity. Here, we sought investigate the effects of long-term statins use on accumulation in and elucidate whether potential mechanism is related SREBP1. Surprisingly, three kinds preclinical diabetic mouse model, treatment induced dysfunction mice, via accelerated fibrosis inflammation. We confirmed that endogenous fatty acids (FA)...
Introduction: Advances in cancer therapies have significantly improved patient survival. However, prolonged tumor-bearing (TB) survival makes the originally hidden cardiovascular disease become an increasingly important cause of death tumor patients. In addition, some commonly used chemotherapeutic agents, such as doxorubicin (DOX), definite cardiotoxicity. Moreover, epidemiological studies found higher risks patients than general population. This study aimed to investigate if TB state leads...