A5046610786- Bariatric Surgery and Outcomes
- Diet and metabolism studies
- Body Contouring and Surgery
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Colorectal Cancer Surgical Treatments
- Obesity and Health Practices
- Esophageal and GI Pathology
- Gastroesophageal reflux and treatments
- Cancer Research and Treatments
- Colorectal and Anal Carcinomas
- Hernia repair and management
- Cancer Cells and Metastasis
- Cancer Immunotherapy and Biomarkers
- Intestinal and Peritoneal Adhesions
- Immunotherapy and Immune Responses
- Eating Disorders and Behaviors
- Obesity, Physical Activity, Diet
- Gastrointestinal motility and disorders
- Immune Cell Function and Interaction
- Appendicitis Diagnosis and Management
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Screening and Detection
- Genetic factors in colorectal cancer
- Diabetes Treatment and Management
Universitätsklinikum Würzburg
2005-2025
Tecan (Switzerland)
2021-2024
University Hospital of Zurich
2020-2024
University of Zurich
2021-2024
RoMed Kliniken
2013-2016
Schön Klinik Bad Aibling
2013-2015
University of Würzburg
1998-2013
Universitäts-Kinderklinik Würzburg
2010-2012
European Neuroendocrine Tumor Society
2010-2012
American Red Cross
2006
Roux-en-Y reconstruction with and without jejunal pouch was compared in a randomized controlled trial to identify the optimal procedure terms of quality life.Randomized trials comparing techniques after total gastrectomy have shown controversial results.One hundred thirty-eight patients gastric cancer were intraoperatively for (n = 71) or 67) stratified into curative palliative resection. Intra- postoperative complications recorded. Body weight life determined every 6 months follow-up up 12...
The trace element selenium is discussed as a chemopreventive agent in colorectal carcinogenesis. Selenocysteine-containing proteins, so-called selenoproteins, represent potential molecular targets for nutritive supplementation. Due to their antioxidative potential, the selenoproteins gastrointestinal glutathione peroxidase (GI-GPx) and selenoprotein P (SePP) are considered provide protection against reactive oxygen species (ROS), thereby reducing DNA damage preventing development of colon...
To define "best possible" outcomes for secondary bariatric surgery (BS).Management of poor response and long-term complications after BS is complex under-investigated. Indications types reoperations vary widely postoperative complication rates are higher compared to primary BS.Out 44,884 performed in 18 high-volume centers from 4 continents between 06/2013-05/2019, 5,349 (12%) cases were identified. Twenty-one outcome benchmarks established low-risk patients, defined as the 75th percentile...
To retrospectively analyse the effectiveness of bariatric surgery for hypothalamic obesity in patients with craniopharyngioma (CP).Patients who developed morbid after CP and underwent laparoscopic gastric banding (LAGB), sleeve gastrectomy or bypass were included (n = 9). Patients common served as controls (LAGB n 40, 49 54).CP was diagnosed during childhood adolescence [median (range) 10 (1-21) years] age at 17 [12-30] years. Six follow-up 5.5 years (range 1-9)], 4 had a 2 (0.4-4) two...
The aim of the study was to evaluate safety and effectiveness a novel closed-loop gastric electric stimulation device (abiliti system) featuring transgastric sensor detect food intake an accelerometer record physical activity induce maintain lifestyle changes treat obesity.In prospective, multi-center study, 34 obese subjects (BMI 42.1 ± 5.3 kg/m(2)) who passed eligibility evaluation were implanted with abiliti system. Safety included endoscopic exam assess intragastric electrode healing....
Recently, robotic surgery has been increasingly performed in hernia surgery. Although feasibility and safety of robot-assisted inguinal repair an inpatient setting have already shown, its role outpatient not yet investigated. Thus, this study aimed to compare TAPP (r-TAPP) conventional laparoscopic (l-TAPP) setting.A prospective database patients with treated by l-TAPP or r-TAPP during a 1-year period was analyzed comparative cohort study. All underwent check-up appointment their surgeon...
To elucidate whether duodenal-jejunal-bypass (DJB), which improves blood glucose control, changes activity of Na-D-glucose cotransporter SGLT1 in small intestine.DJB has been shown to improve oral tolerance normal rats and a genetic diabetic rat model. Because intestinal D-glucose absorption is mediated by localized the brush border membrane enterocytes, it unclear function altered DJB this contributes improvement glycemic control.A high-fat diet low-dose streptozotocin administration were...
Abstract Background The local and systemic activation regulation of the immune system by malignant cells during carcinogenesis is highly complex with involvement innate acquired system. Despite fact that do have antigenic properties their immunogenic effects are minor suggesting tumor induced mechanisms to circumvent cancer immunosurveillance. aim this study analysis escape in a colorectal liver metastases mouse model at different points time growth. Methods CT26.WT murine colon carcinoma...
The aim of this study is to evaluate the accuracy outcome reporting after elective visceral surgery in a low volume district hospital. Outcome measurement as well transparent surgical complications becomes more and important. In future, financial personal resources may be distributed due reported quality thus, it main interest healthcare providers that data are accurately collected. Between 10/2020 09/2021 postoperative during hospitalisation were recorded using Clavien–Dindo classification...
Gastrointestinal stromal tumors (GISTs) are most often associated with oncogenic mutations of the KIT gene resulting in activation tyrosine kinase receptor KIT. Familial GIST syndrome based on a hereditary predisposition to develop owing germline mutation is exceedingly rare. We describe kindred familial displaying novel exon 17. Three siblings (2 females, 1 male; 42 49 y) underwent surgery for multiple intra-abdominal within 3-year period. Their father had been operated gastric and jejunal...
The development of new therapeutic strategies for treatment metastasized colorectal carcinoma requires biologically relevant and adequate animal models that generate both reproducible metastasis the dissemination tumor cells in form so-called minimal residual disease (MRD), an expression systemic character neoplastic disease.We injected immunoincompetent nude mice intraportally with different numbers (1 x 10(5), 1 10(6) 5 cells) human colon cell lines HT-29 SW-620 investigated by...