A5014844497- Cardiovascular Health and Disease Prevention
- Blood Pressure and Hypertension Studies
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Nitric Oxide and Endothelin Effects
- Hemodynamic Monitoring and Therapy
- Heart Rate Variability and Autonomic Control
- Cardiac Ischemia and Reperfusion
- Cardiovascular and exercise physiology
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Coronary Interventions and Diagnostics
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Non-Invasive Vital Sign Monitoring
- Neuropeptides and Animal Physiology
- Protease and Inhibitor Mechanisms
- Receptor Mechanisms and Signaling
- Pain Management and Treatment
- Blood Coagulation and Thrombosis Mechanisms
- Cardiovascular Disease and Adiposity
- Cerebrovascular and Carotid Artery Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac and Coronary Surgery Techniques
- Cardiomyopathy and Myosin Studies
University of Florida
2011-2024
Université Paris Cité
2016-2017
University of Tasmania
2016-2017
École Polytechnique
2016-2017
Assistance Publique – Hôpitaux de Paris
2016-2017
Brunel University of London
2016-2017
McGill University
2017
National and Kapodistrian University of Athens
2017
École Polytechnique Fédérale de Lausanne
2016
Barber-Nichols (United States)
2015
M uch has been published in the past 20 years on use of measurements arterial stiffness animal and human research studies.This summary statement was commissioned by American Heart Association to address issues concerning nomenclature, methodologies, utility, limitations, gaps knowledge this rapidly evolving field.The following represents an executive version larger online-only Data Supplement is intended give reader a sense why important, how it measured, situations which useful, its...
To determine the systemic input impedance, pulsatile pressure and flow were measured in ascending aorta 16 human subjects who undergoing diagnostic cardiac catheterization. Blood was with a catheter-tip electromagnetic velocity meter, an external transducer connected fluid-filled lumen of catheter. Five found to have no evidence cardiovascular disease (group A, mean age 32 +/- 2 years, aortic 97 4 mm Hg). Seven had clinical angiographic signs coronary arterial disease, pressures less than...
In vitro fertilization involving frozen embryo transfer and donor oocytes increases preeclampsia risk. These in protocols typically yield pregnancies without a corpus luteum (CL), which secretes vasoactive hormones. We investigated whether CL disrupt maternal circulatory adaptations increase Women with 0 (n=26), 1 (n=23), or >1 (n=22) were serially evaluated before, during, after pregnancy. Because increasing arterial compliance is major physiological adaptation pregnancy, we assessed...
The effect of moderate left ventricular systolic dysfunction (LVSD) on ventricular/vascular coupling and the aortic pressure waveform (AoPW) has been well described, but severe LVSD not.We used noninvasive, high-fidelity tonometry radial artery a mathematical transfer function to generate AoPW in 25 treated patients with (mean LV ejection fraction, 24+/-8.8%; range, 11% 40%; 21 <30%). Pulse wave analysis was characterize compared pulse performed normal subjects matched for age, gender,...
Journal Article Effect of glyceryl trinitrate on peripheral arteries alters left ventricular hydraulic load in man Get access TOSHIO YAGINUMA, YAGINUMA From the Department Medicine, University New South Wales, St Vincents Hospital, Sydney, Australia Search for other works by this author on: Oxford Academic PubMed Google Scholar ALBERTO AVOLIO, AVOLIO MICHAEL O'ROURKE, O'ROURKE WILMER NICHOLS, NICHOLS JOHN J MORGAN, MORGAN PAUL ROY, ROY DAVID BARON, BARON BRANSON, BRANSON FENELEY...
Several methods have been used to measure left ventricular regional blood flow in humans. However, limitations and lack of validation patients are major problems. A continuous thermodilution technique with coronary disease was validated vivo. This permits simultaneous assessment venous draining predominantly from the anterior wall total effluent. Thermodilution measurements electromagnetic flowmeter recordings descending vein grafts were compared occluded or subtotally arteries. The method...
The input impedance of the systemic circulation was calculated from recordings pulsatile pressure and flow in ascending aorta 20 patients. Ten patients had clinical hemodynamic evidence heart failure. other 10 subjects no failure were used as a control group. In patients, both resistance characteristic (index aortic distensibility) significantly increased compared to pressure- age-matched subjects. Oscillations moduli, represented by difference between maximum minimum also with these...
Background— Mechanisms responsible for anti-ischemic benefits of enhanced external counterpulsation (EECP) remain unknown. This was the first randomized sham-controlled study to investigate extracardiac effects EECP on peripheral artery flow-mediated dilation. Methods and Results— Forty-two symptomatic patients with coronary disease were (2:1 ratio) thirty-five 1-hour sessions either (n=28) or sham (n=14). Flow-mediated dilation brachial femoral arteries performed use ultrasound. Plasma...
OBJECTIVE—To determine if children with type 1 diabetes have increased arterial stiffness by estimating augmentation index the simple noninvasive technique of radial artery tonometry. RESEARCH DESIGN AND METHODS—We studied 98 diabetic and 57 healthy control subjects, ages 10–18 years, matched for age, sex, race, BMI, generating 43 pairs. Radial tonometry was performed, blood collected analysis fasting lipids, HbA1c, glucose, cytokines in all children. RESULTS—Children had a significantly...
Previous studies indicate impairment of coronary arterial ring relaxation in response to acetylcholine (ACh) following reperfusion, mediated via loss endothelium-derived relaxing factor (EDRF). To examine if vasodilator reserve is reduced occlusion-reperfusion intact animals, 16 open-chest mongrel dogs were subjected 1 hour total left circumflex (Cx) artery occlusion followed by reperfusion for hour. Prior Cx occlusion, blood flow increased and vascular resistance decreased (both p less than...
The acute coronary hemodynamic and metabolic effects of intravenous dipyridamole were studied in 13 patients. Total left ventricular (LV), anterior (supplied by the descending artery) inferior circumflex right arteries) regional flows responses assessed from sinus great cardiac vein. Perfusion to LV regions was classified as potentially "normal" or "abnormal," based on angiographic findings. Before dipyridamole, flow, oxygen delivery lactate extraction both normal abnormal similar. Within 1...
Abstract —The mutant form of human apoA1, known as apoA1 Milano, is formed a result arginine 173 to cysteine substitution and inhibits experimental atherosclerosis in cholesterol-fed animals. This study was designed determine if Milano would modify arterial thrombogenesis. Sprague Dawley rats were intravenously administered the carrier alone (n=8) or (20 mg · kg −1 d for 4 10 days, n=17). The abdominal cavity opened, aorta isolated. Whatman paper impregnated with 35% FeCl 3 wrapped around...