A5053435021- High Temperature Alloys and Creep
- Cardiomyopathy and Myosin Studies
- Microstructure and Mechanical Properties of Steels
- Nuclear Materials and Properties
- Fatigue and fracture mechanics
- Adipokines, Inflammation, and Metabolic Diseases
- Adipose Tissue and Metabolism
- Calcium Carbonate Crystallization and Inhibition
- Metal Alloys Wear and Properties
- Fusion materials and technologies
- Refrigeration and Air Conditioning Technologies
- Neuroscience and Neuropharmacology Research
- Metal and Thin Film Mechanics
- Muscle Physiology and Disorders
- RNA Research and Splicing
- Engineering Applied Research
- Phase-change materials and chalcogenides
- Cholinesterase and Neurodegenerative Diseases
- Face and Expression Recognition
- Fire effects on concrete materials
- Wound Healing and Treatments
- Marine Bivalve and Aquaculture Studies
- Aerodynamics and Fluid Dynamics Research
- biodegradable polymer synthesis and properties
- Skin Protection and Aging
Shionogi (Japan)
1998-2025
Keio University
2025
Muroran Institute of Technology
2015-2024
Futaba (Japan)
1998-2020
Osaka University
2005-2019
Nippon Steel (Japan)
2006-2017
Nippon Steel (Germany)
2017
Mitsubishi Heavy Industries (Germany)
2005-2016
Tokyo University of Science
2015
Denso (United States)
2011
An all-optical network is identified as a promising infrastructure for fast and energy-efficient communication. Recently, it has been shown that its quantum version based on 'all-photonic repeaters'-inheriting, at least, the same advantages-expands possibility to realm, is, global internet with applications far beyond conventional Internet. Here we report proof-of-principle experiment key component all-photonic repeaters-called time-reversed adaptive (TRA) Bell measurement, proposal...
Novel supramolecular polymers have been prepared from a β-cyclodextrin dimer and ditopic guest having adamantyl groups. β-Cyclodextrins were bound to poly(ethylene glycol) (PEG, Mn 600). Adamantyl groups also PEG (Mn The ROESY NMR spectrum of 1:1 mixture the adamantane showed ROE correlations between protons substituents inner β-cyclodextrin. Molecular weights molecular sizes polymer constructed by investigated pulse field gradient spin echo (PFGSE) vapor pressure osmometry (VPO). results...
Lignosulfonic acid is a waste lignin produced from the sulfite pulping of softwood. We investigated effect lignosulfonic on α-glucosidase and found that reversible non-competitive inhibition enzyme activity. Moreover, in human colorectal adenocarcinoma cells, inhibited 2-deoxyglucose uptake, while vivo studies demonstrated significant reduction blood glycemic response to sucrose or glucose ingestion rats treated with acid. Feces fed diet supplemented 5% had higher sugar content compared...
Journal Article Role of 17-kDa Essential Light Chain Isoforms Aorta Smooth Muscle Myosin Get access Yasushi Hasegawa, Hasegawa Department Chemistiy, Faculty Science, Hokkaido UniversityKita-ku, Sapporo, 060 Search for other works by this author on: Oxford Academic PubMed Google Scholar Fumi Morita The Biochemistry, Volume 111, Issue 6, June 1992, Pages 804–809, https://doi.org/10.1093/oxfordjournals.jbchem.a123840 Published: 01 1992 history Received: 20 February
Pearl oysters have been extensively utilized in pearl production; however, most oyster shells are discarded as industrial waste. In a previous study, we demonstrated that the intraperitoneal administration of shell-derived nacre extract (NE) prevented d-galactose-induced brain and skin aging. this examined anti-aging effects orally administered NE senescence-accelerated mice (SAMP8). Feeding SAMP8 development aging-related characteristics, such coarse dull hair, which commonly observed aged...
Abstract Background A novel antifungal compound, COT-832 was created by SHIONOGI through modifying Amphotericin B (AmB). Marketed AmB formulations are often discontinued in clinical use due to nephrotoxicity. In this study, we investigated vivo efficacy of against Aspergillus fumigatus (A. fumigatus) and Candida albicans (C. albicans) mice rats infection models comparison with those Fungizone (FGZ) AmBisome (L-AMB) at each human clinically equivalent dose (CED) AUC. Methods CED; Mice (male...
Pearl and nacre have been used in traditional medicines for treating brain dysfunctions, such as epilepsy, myopia, palpitations convulsions. We previously showed that a pearl oyster extract improves scopolamine-induced memory impairments using the Y-maze, Banes maze object recognition tests. In this study, we aimed to isolate memory-improving substance ion-exchange column chromatography reverse-phase elucidate molecular mechanism underlying its activity. The isolated was found be sulfated...
To evaluate the neuroprotective effects of organic components scallop shells (scallop shell extract) on memory impairment and locomotor activity induced by scopolamine or 5-methyl-10,11-dihydro-5H-dibenzo (a,d) cyclohepten-5,10-imine (MK801).Effect extract was investigated using Y-maze test, Morris water maze open field test.Scallop significantly reduced scopolamine-induced short-term partially spatial in test. Scallop suppressed elevation acetylcholine esterase cerebral cortex. Treatment...
Pearl powder (nacreous layer) has been used in traditional Chinese medicine, as well functional foods and cosmetics. The present study was undertaken to investigate the beneficial effects of extract from nacreous layer pearl oyster shells (nacre extract) lipopolysaccharide (LPS)-induced depression anxiety mice. Nacre treatment improved depression-and anxiety-like behaviors prevented oxidative stress by increasing expression nuclear factor E2-related (Nrf2). We found that LPS decreased...
Aorta myosin contains two kinds of light chain, 20-kDa phosphorylatable chain and 17-kDa essential (LC17). Purified from porcine aorta media showed 3 distinct bands on polyacrylamide gel electrophoresis (PAGE) in the presence urea (urea-PAGE). The mobilities faster components did not change after incubation with a kinase. Gel slices containing were separately subjected to PAGE sodium dodecylsulfate. Both identical mobility that LC17. designated as LC17a LC17b increasing order urea-PAGE. They...
The microstructure of a Type IV damage, ductile and early creep failure at outer edge Heat Affected Zone weld, was precisely researched. rupture life simulated fine grain area HAZ the shortest compared with those other microstructures, coarse dual phase HAZ, according to temperature acceleration test 700°C. tensile strength room lowest around Ac1 transformation point, determined by rapid heating diratometry. Therefore, damage did not coincident conventional softening phenomenon often...
A small punch (SP) creep test was applied to the welded joint of a boiler header (1.0Cr–0.3Mo steel), which had been actually used for around 250 000 h, evaluate changes in properties. miniaturized plate-type specimen 10×10×0.5 mm taken from base metal, weld metal and heat affected zone (HAZ), respectively, SP microstructure observation. Experimental results revealed that rupture strength each portion decreased by long-term service exposure, especially high stress (load) conditions. The time...