Shamima Akhter

ORCID: 0000-0003-1960-9273
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About
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Research Areas
  • Agricultural Economics and Practices
  • Synthesis and biological activity
  • Inflammatory mediators and NSAID effects
  • Nanoplatforms for cancer theranostics
  • Cancer, Stress, Anesthesia, and Immune Response
  • Reproductive Health and Contraception
  • DNA Repair Mechanisms
  • Wheat and Barley Genetics and Pathology
  • Anaerobic Digestion and Biogas Production
  • Cancer, Lipids, and Metabolism
  • Rice Cultivation and Yield Improvement
  • Maternal and fetal healthcare
  • Computational Drug Discovery Methods
  • Anesthesia and Pain Management
  • PI3K/AKT/mTOR signaling in cancer
  • Psoriasis: Treatment and Pathogenesis
  • Plant Taxonomy and Phylogenetics
  • Syphilis Diagnosis and Treatment
  • Chemokine receptors and signaling
  • Pain Management and Treatment
  • Extracellular vesicles in disease
  • Global Educational Policies and Reforms
  • Salivary Gland Tumors Diagnosis and Treatment
  • Agricultural Systems and Practices
  • Respiratory Support and Mechanisms

National Institute of Traumatology & Orthopaedic Rehabilitation
2025

Dhaka Medical College and Hospital
2018-2025

University of Helsinki
2024

Dhaka University of Engineering & Technology
2023

The University of Texas MD Anderson Cancer Center
2009-2023

University of Dhaka
2023

Bangladesh Agricultural University
2013-2023

Shaheed Suhrawardy Medical College
2013-2022

Khulna Medical College
2021

University of Asia Pacific
2021

Diclofenac (DCF) is a non-steroidal anti-inflammatory drug (NSAID), commonly used for the treatment of pain. It can inhibit prostaglandin synthesis by blocking cyclooxygenase (COX). shows some crucial side effects like gastrointestinal, cardiovascular, renal, and liver injury. The gastrointestinal injury occurred due to presence carboxylic (COOH) group at core DCF. hydroxyl (OH) portion COOH was replaced inserting new functional groups (CH3, OCH3, CH2NH2, NH2, NHCOCH3, NHCONH2, Cl, CF3)...

10.1016/j.imu.2023.101159 article EN cc-by-nc-nd Informatics in Medicine Unlocked 2023-01-01

We identified ubiquitin-like with PHD and RING finger domain 1 (UHRF1) as a binding factor for DNA interstrand crosslink (ICL) lesions through affinity purification of ICL-recognition activities. UHRF1 is recruited to in vivo binds directly ICL-containing DNA. UHRF1-deficient cells display increased sensitivity variety damages. found that loss led retarded lesion processing reduced recruitment ICL repair nucleases the site damage. interacts physically both ERCC1 MUS81, two involved lesions....

10.1016/j.celrep.2015.03.038 article EN cc-by Cell Reports 2015-03-01

Akt is a critical mediator of the oncogenic PI3K pathway, and its activation regulated by kinases phosphatases acting in opposition. We report here existence novel protein complex that composed minimally Akt, PHLPP1, PHLPP2, FANCI, FANCD2, USP1 UAF1. Our studies show depletion but not FANCD2 or USP1, results increased phosphorylation Akt. This due to reduction interaction between PHLPP1 absence FANCI. In response DNA damage growth factor treatment, interactions FANCI are reduced consistent...

10.1080/15384101.2016.1158375 article EN Cell Cycle 2016-04-17

Background: Brachial plexus block is a widely used regional anesthesia technique for upper limb surgeries. Multidrug regimens incorporating lidocaine, bupivacaine, and dexamethasone aim to enhance efficacy while maintaining safety. This study evaluates the comparative safety of three brachial using in patients undergoing Methods: A retrospective cohort was conducted involving 150 Block assessed through onset duration sensory motor blockades, along with pain scores Visual Analog Scale (VAS)....

10.36347/sasjs.2025.v11i01.008 article EN SAS Journal of Surgery 2025-01-13

2057 Background: Glioblastoma (GBM), the most common primary brain tumor in adults, has a poor prognosis despite standard treatment. This meta-analysis evaluates efficacy and safety of Bevacizumab, VEGF inhibitor, when combined with radiotherapy Temozolomide terms progression-free survival (PFS), overall (OS), treatment-related adverse events. Methods: A systematic search PubMed, Cochrane Library, Embase, ClinicalTrials.gov identified randomized controlled trials (RCTs) evaluating...

10.1200/jco.2025.43.16_suppl.2057 article EN Journal of Clinical Oncology 2025-05-28

CONTEXT: Treatment of complications unsafe abortion can be a significant financial drain on health system resources,particularly in developing countries.In Bangladesh,menstrual regulation is provided by the government as backup to contraception.The comparison economic costs providing menstrual care with those treatment has implications for policy Bangladesh and internationally.METHODS: Data incremental were collected through surveys providers at 21 public-sector facilities Bangladesh.These...

10.1363/3619710 article EN International Perspectives on Sexual and Reproductive Health 2010-12-01

Introduction. Phyllodes tumors are rare fibroepithelial which constitute less than 1% of all known breast neoplasms. The importance recognizing these lies in the need to differentiate them from fibroadenomas and other benign lesions avoid inappropriate surgical management. We report a case large phyllodes tumor caused rupture presented as an external fungating mass, presentation is exceedingly rare. Case Presentation. A 32-year-old female with 1-year history mass her right eruption through...

10.1155/2013/871292 article EN cc-by Case Reports in Oncological Medicine 2013-01-01

The study investigated the distinct environmental impacts and economic viability of domestic biogas technology in countryside Bangladesh. was carried out by a survey through personal interviews with users. Seventy households were selected purposively conducted semi-structured questionnaires. mainly highlighted potential reduction greenhouse gas (GHG) emission benefits utilization which evaluated considering substitution traditional biomass fuels, saving Liquefied Petroleum Gas (LPG) cost...

10.5539/jsd.v14n5p44 article EN Journal of Sustainable Development 2021-08-20

This study was conducted to estimate the relative profitability of Maize production under different farm size groups. Data were collected from randomly selected 74 maize growing farmers which 25 small, 32 medium and 17 large considering scope potentials at Kishoregonj district. To achieve objectives study, descriptive statistical techniques such as sum, average, standard deviation etc, used. The major findings showed that per hectare average total costs Tk. 30,147.54, 31,892.00 34,059.00 for...

10.3329/pa.v21i1-2.16781 article EN Progressive Agriculture 2013-11-02

This observational study was carried out as a preliminary one to see the effectiveness and reliability of an easy noninvasive approach for confirmatory diagnosis Visceral Leishmaniasis (VL) by detection amastigote forms (LD bodies) parasite. Clinically suspected 73 febrile cases were investigated examination bone marrow/splenic aspirate detect LD bodies, whom 57 (41.61%) showed positive result on microscopy and/or culture in modified Novy, Nichole, MacNeal (NNN) medium. Blood buffy coat...

10.3329/bjmm.v1i2.21507 article EN Bangladesh Journal of Medical Microbiology 2016-05-25

This study was conducted to estimate the comparative profitability of Aftab Bahumukhi Farm Limited (ABFL) supervised broiler farms and farmers’ own managed farms. Data were collected from randomly selected 90 farmers which 45 ABFL farmers. Descriptive statistical techniques used cost returns farming. The revealed that on an average, total raising per batch 1000 birds estimated at Tk. 99,429.00 1,06,330.00 for respectively. respective average variable costs fixed calculated 96,218.00...

10.3329/pa.v20i1-2.16875 article EN Progressive Agriculture 2013-11-05

Abstract One of the performance indicators for assessment ongoing water floods is concept Voidage Replacement Ratio (VRR). Often, it has been experienced that VRR numbers are either used or abused during waterflood management leading to inconsistent decisions. Coupled with injection efficiency, becomes a powerful tool manage mega size flood in Kuwait. The paper an attempt examine various sources errors reporting VRRs and suggest deep-dive approach, rather than simplistic methodology. Amongst...

10.4043/34799-ms article EN 2024-02-22

Background: Now a day’s bacterial vaginosis is an extremely common health problem for women in the world which causes many complications both pregnancy and non-pregnancy states. G. vaginalis most important cause of vaginosis.Methods: A prospective observational study was conducted to detect their sensitivity patterns on patients attending at outpatient Department Gynaecology Obstetrics Chittagong Medical College Hospital, Chittagong. total 170 sexually active female age group 15-45 years,...

10.3329/cmoshmcj.v16i1.34987 article EN Chattagram Maa-O-Shishu Hospital Medical College Journal 2017-12-26

<title>Abstract</title> <italic>Chlamydomonas</italic> <italic>malina</italic> is a polar microalga with high PUFA production under phototrophic conditions. In this study, <italic>C. malina</italic>, strain RCC2488, was cultivated on glucose and potato peel hydrolysates (PPH), at 120 µmol photons m<sup>-2</sup> s<sup>-1</sup> of light intensity, to investigate the feasibility growing mixotrophic Potato peels were subjected an acid-hydrothermal pretreatment. The resulting material separated...

10.21203/rs.3.rs-5321861/v1 preprint EN cc-by Research Square (Research Square) 2024-11-06

&lt;p&gt;&lt;em&gt;Background:&lt;/em&gt; Dengue virus infections are a significant threat to human populations particularly in the tropical and subtropical regions. This is mainly transmitted by Aedes aegypti mosquito from humans humans. The main pathological mechanisms associated include thrombocytopenia, haemorrhagic diathesis with haemoconcentration. Ultrasonography used because of its ability detect plasma leakage signs prediction disease severity.&lt;/p&gt;...

10.3329/bmrcb.v47i1.55794 article EN Bangladesh Medical Research Council Bulletin 2022-05-17

Resorcinol with its two hydroxyl groups was derivatized in laboratory to observe the anti-inflammatory potential vitro. Subsequently silico docking analysis done for observing binding modes cyclooxygenase enzyme have idea about subsequent possible developments. At doses of 200 mg/ml and 400 mg/ml. compounds showed property, where 02 offered dose dependent 51% 70% inhibition heat induced hemolysis respectively. The scaffold thus poses as an interesting pharmacophore suitable lead generation...

10.22144/ctu.jen.2020.027 article EN cc-by-nc Can Tho University Journal of Science 2020-11-29

The purposes of the study were to determine extent training need rural women participating in IGAs supported by SUS (Sabalamby Unnayan Samity) and relate with their selected characteristics. Data collected from 105 respondents ten villages Sadar Upazila Netrokona district through interview schedule April 2007. Most high for better performance participation SUS. relationships between characteristics tested computing co-efficient correlation. Education, farm size, credit received found...

10.3329/pa.v18i2.18384 article EN Progressive Agriculture 2014-03-20

Hepatitis C infection is a serious health issue worldwide caused by hepatitis virus (HCV). There an urgent need of search for new direct acting antiviral drugs due to the rapid development drug resistance. The HCV NS5A protein involved in creating resistance against therapy and there are also many reports that vitamin A deficiency associated with non-responsiveness treatment infected patients. So present silico study was aimed find relation between protein's function Structure predicted...

10.4149/av_2017_02_11 article EN Acta Virologica 2017-01-01

Background: Diabetes mellitus is one of the most widespread endocrine disorders in female and its complications are increasing all over world, leading to life threatening medical problems like cardiovascular diseases, stroke end stage renal diseases. A correlation between hyperlipidemia type 2 diabetes has been identified. The study was carried out observe serum low density lipoprotein cholesterol (LDL-C) high (HDL-C) level with adult subjects.Method: This cross sectional conducted...

10.3329/jdmc.v26i2.38832 article EN Journal of Dhaka Medical College 2018-11-18
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