A5031135898- Retinal Imaging and Analysis
- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Retinal and Macular Surgery
- Retinal and Optic Conditions
- Intraocular Surgery and Lenses
- Retinal Development and Disorders
- Ocular Diseases and Behçet’s Syndrome
- Traumatic Ocular and Foreign Body Injuries
- Renal Diseases and Glomerulopathies
- Vascular Malformations Diagnosis and Treatment
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Sinusitis and nasal conditions
- Vasculitis and related conditions
- Intracranial Aneurysms: Treatment and Complications
- Ocular Infections and Treatments
- Retinopathy of Prematurity Studies
- Photoreceptor and optogenetics research
- Pituitary Gland Disorders and Treatments
- Facial Trauma and Fracture Management
- Ureteral procedures and complications
- Dermatological and Skeletal Disorders
- Biosensors and Analytical Detection
- Ophthalmology and Eye Disorders
- Corneal Surgery and Treatments
Instituto Mexicano de Oftalmología IAP
2017-2024
Universidad Nacional Autónoma de México
2020-2023
Institute of Ophthalmology
2020-2022
Institut de Chimie de Nice
1997
Purpose: High circulating levels of the hormone prolactin (PRL) protect against experimental diabetic retinopathy (DR) due to retinal accumulation vasoinhibin, a PRL fragment that inhibits blood vessel permeability and growth. A phase 2 clinical trial is investigating new therapy for DR based on elevating serum with levosulpiride, prokinetic dopamine D2 receptor blocker. Here, we tested whether levosulpiride-induced hyperprolactinemia elevates vasoinhibin in vitreous volunteer patients...
Given the ever-increasing prevalence of type 2 diabetes and obesity, pressure on global healthcare is expected to be colossal, especially in terms blindness. Electroretinogram (ERG) has long been perceived as a first-use technique for diagnosing eye diseases, some studies suggested its use preventable risk factors thereby diabetic retinopathy (DR). Here, we show that non-evoked mode, ERG signals contain spontaneous oscillations predict disease cases rodent models obesity people with...
The purpose of the study is to describe visual and anatomic outcomes 5774nm micropulse laser photocoagulation in eyes with either treatment-naïve or refractory diabetic macular edema (DME) at 3 months.This was a prospective case series that recruited 23 consecutive patients (33 eyes) center-involved DME had not responded prior treatment. Micropulse therapy performed Easy Ret 577 (Quantel Medical, Cournon d'Auvergne, France) diode high-density manner DME. primary outcome change best-corrected...
Abstract Background/Objective The prokinetic levosulpiride elevates vasoinhibin levels in the vitreous of patients with proliferative diabetic retinopathy (PDR) suggesting clinical benefits due to anti-vasopermeability and anti-angiogenic properties vasoinhibin. We investigated biological activity centre-involving macular oedema (DME). Patients/Methods Prospective, randomized, double-blinded, dual-centre, phase 2 trial DME orally treated placebo ( n = 17) or for 8 weeks PDR undergoing...
Objective: To determine normal macular thickness values in a healthy Mexican population and its variation by age gender using Huvitz spectral-domain optical coherence tomography (HOCT-1F). Methods: This cross-sectional study included 211 consecutive eyes from clinically subjects (66 men, 145 women) between October 2018 December 2018, with best-corrected visual acuities better than 20/30. One eye was selected for the scan OCT (Huvitz OCT-1F, HOCT-1F, Co., Ltd., Republic of Korea) an automated...
Abstract Diabetic Macular Edema (DME) is the most common sight-threatening complication of type 2 diabetes. Our goal was to develop an alternative method optical coherence tomography (OCT) for DME diagnosis by introducing spectral information derived from spontaneous electroretinogram (ERG) signals as a single input or combined with eye fundus. To this end, observational study completed (n = 233 participants). Basal ERGs were used generate scalograms and spectrograms via Wavelet Fourier...
It has been reported that intravitreal Ziv-aflibercept is a safe and effective drug for the treatment of diabetes macular edema (DME). The objective this study was to evaluate in real-life setting, efficacy DME after administration three consecutive monthly doses.A single arm, prospective cohort study. We included patients with who received doses Ziv-aflibercept. Data such as best corrected visual acuity (BCVA) tomographic biomarkers before month third dose were collected. staged using...
ABSTRACT Vision loss due to chronic-degenerative diseases is a primary cause of blindness worldwide. Deep learning architectures utilizing optical coherence tomography images have proven effective for the early diagnosis ocular pathologies. Nevertheless, most studies emphasized best outcomes using optimal hyperparameter combinations and extensive data availability. This focus has eclipsed exploration how model capacity varies with different volumes. The current study evaluates capabilities...
Abstract Given the ever-increasing prevalence of type 2 diabetes and obesity, pressure on global healthcare is expected to be colossal, especially in terms blindness. Electroretinogram (ERG) has long been perceived as a first-use technique for diagnosing eye diseases, some studies suggested its use preventable risk factors thereby diabetic retinopathy (DR). Here, we show that non-evoked mode, ERG signals contain spontaneous oscillations predict disease cases rodent models obesity people with...
Appropriate medical management can be an alternative in those patients with submacular cysticercosis whom achieving good visual outcome vitreoretinal surgery is not possible. We report the case of a 25-year-old female who presented complaining blurred vision her left eye associated photopsias and metamorphopsias 3 months duration. Initial acuity right was 20/20 20/100 eye. Upon indirect ophthalmoscopy eye, yellow-white, dome-shaped, elevated lesion foveal involvement observed. The rest...
Purpose: We present a case of hemorrhagic choroidal detachment associated with surgical induced diffuse scleritis (SIDS) following phacoemulsification surgery. Case report: A-49-year-old healthy male history high myopia and pars-plana vitrectomy 360° encircling buckle surgery years ago, who underwent in-the-bag intraocular lens implantation on the right eye developed an important first-day post-surgery, 10 days later, presented SIDS. First day after surgery, best-corrected visual acuity was...
We report 2 cases of an aggressive choroidal neovascularization phenotype. A 77-year-old hypertensive woman, with a 4-year history visual loss in her left eye, due to vitreous hemorrhage associated dome-shaped mass lesion underwent pars plana vitrectomy. An extensive subretinal was found, fibrosis, which treated endophotocoagulation and intravitreal injection anti-VEGF. Best-corrected acuity after surgery light perception. 74-year-old woman treatment for both eyes presented exudation the...
Abstract Given the ever-increasing prevalence of type 2 diabetes and obesity, pressure on global healthcare is expected to be colossal, especially in terms blindness. Electroretinogram (ERG) has long been perceived as a first-use technique for diagnosing eye diseases, but existing methods are insufficient screen early risk factors diabetic retinopathy (DR). Here, we introduce non-evoked ERG simple, fast modality record spontaneous activity, from which developed single random forest-based...
This work examines the relationship between first- and third-month anatomical visual response with antivascular endothelial growth factor for diabetic macular edema.We prospectively evaluated 58 eyes center-involved edema. Response was categorized upon status after 3 monthly doses based on reduction of central thickness (CMT) from baseline (≥20% or not). Correlation analysis status, gained letters, optical coherence tomography morphological features, other characteristics were...