- Clostridium difficile and Clostridium perfringens research
- Pharmacological Effects of Natural Compounds
- Peripheral Neuropathies and Disorders
- Respiratory viral infections research
- Viral gastroenteritis research and epidemiology
- Virology and Viral Diseases
- Animal Virus Infections Studies
- Microbial infections and disease research
- Animal health and immunology
- Vascular Malformations and Hemangiomas
- Pleural and Pulmonary Diseases
- Glioma Diagnosis and Treatment
- Lymphatic Disorders and Treatments
- Ear and Head Tumors
- Occupational and environmental lung diseases
- Tumors and Oncological Cases
- Ocular Oncology and Treatments
- Veterinary Oncology Research
- Tracheal and airway disorders
- Freshwater macroinvertebrate diversity and ecology
- Teratomas and Epidermoid Cysts
- Lepidoptera: Biology and Taxonomy
- Vitamin C and Antioxidants Research
- Neonatal Respiratory Health Research
- Species Distribution and Climate Change
University of Wisconsin–Madison
2023
The Ohio State University
2018-2022
Michigan State University
2015-2018
Hillsdale College
2018
Campylobacter jejuni is the leading antecedent infection to autoimmune neuropathy Guillain-Barré syndrome (GBS), which accompanied by an anti-ganglioside antibody attack on peripheral nerves. Previously, we showed that contrasting immune responses mediate C. induced colitis and autoimmunity in interleukin-10 (IL-10)-deficient mice, dependent upon infecting strain. Strains from patients elicited T helper 1 (TH1)-dependent inflammatory while strains GBS TH2-dependent autoantibody production....
Respiratory syncytial virus (RSV) has been reported to use CX3CR1 in vitro as a receptor on cultured primary human airway epithelial cultures. To evaluate the for RSV vivo, we used cotton rat animal model because of its high permissiveness infection. Sequencing gene revealed 91% amino acid similarity CX3CR1. Previous work found that binds via attachment glycoprotein (G protein) infect determine whether CX3CR1-G protein interaction is necessary infection, recombinant RSVs containing mutations...
We document 134 caddisfly species and their seasonal habitat affinities based on 93 samples collected from 26 sites throughout the Manistee River watershed in lower peninsula of Michigan May through September, 2010. Eleven these species: Banksiola dossuaria (Say), Cheumatopsyche aphanta Ross, pasella Hydroptila xera Ironoquia lyrata (Ross), Lepidostoma vernale (Banks), Neotrichia vibrans Nyctiophylax affinis Oxyethira aeola rivicola Blickle Morse, Polycentropus timesis (Denning) are reported...
A 9-year-old spayed female domestic shorthair cat with clinical signs suggestive of chronic recurrent otitis media and recent seizures was presented multifocal nervous system disease, including bilateral central and/or peripheral vestibular, cerebellar forebrain deficits. Prior to presentation, there inadequate improvement after 6 weeks treatment for middle ear effusion from which a highly susceptible Staphylococcus species cultured. This followed by the development seizures. Results...
Two unrelated bovine beef calves, aged 2 mo and 3 mo, were presented to The Ohio State University Veterinary Medical Center because of scrotal swelling abdominal distension. On postmortem examination, there was abundant peritoneal fluid numerous small friable masses covering all surfaces extending into the scrotum via tunica vaginalis, with no identifiable primary neoplasm. Based on light microscopy, differential diagnoses included malignant mesothelioma anaplastic carcinoma....
Even after decades of intensive research efforts, a safe and efficacious RSV vaccine remains elusive. Expression heterologous antigens from rVSV vectors has demonstrated several practical safety advantages over other virus vector systems live attenuated vaccines.
Abstract Spontaneous intraocular tumors are rarely reported in rabbits, despite their widespread use as laboratory animals. We describe two cases of neuroectodermal embryonal tumors, formerly primitive young rabbits. Histologically, both exhibited prominent rosette or pseudorosettes, consistent with the histomorphology seen human tumors. The subtype is supported by immunoreactivity for neuronal markers, SRY‐box transcription factor 2, microtubule‐associated protein nuclear protein, and...