Pınar Özçelik

ORCID: 0000-0003-1978-1874
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About
Contact & Profiles
Research Areas
  • Vestibular and auditory disorders
  • Migraine and Headache Studies
  • Ophthalmology and Eye Disorders
  • Peripheral Neuropathies and Disorders
  • Myasthenia Gravis and Thymoma
  • Glaucoma and retinal disorders
  • Multiple Sclerosis Research Studies
  • Dementia and Cognitive Impairment Research
  • Circular RNAs in diseases
  • Systemic Lupus Erythematosus Research
  • Cerebral Venous Sinus Thrombosis
  • MicroRNA in disease regulation
  • Retinal Imaging and Analysis
  • Sleep and Work-Related Fatigue
  • Islamic Thought and Society Studies
  • Diet and metabolism studies
  • Neuroblastoma Research and Treatments
  • Muscle Physiology and Disorders
  • Spatial Neglect and Hemispheric Dysfunction
  • Microbial infections and disease research
  • Parkinson's Disease and Spinal Disorders
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Inflammatory Myopathies and Dermatomyositis

Bezmiâlem Vakıf Üniversitesi
2023-2024

Dokuz Eylül University
2014-2023

Biruni University
2023

Bilkent University
2006

Alzheimer's disease (AD) dementia is a degenerative illness that characterized by gradual decline in cognitive abilities. Amnestic mild impairment (aMCI) seen as precursor to AD. The changes antisaccade performance can be MCI may provide important clues the early detection of Therefore, deficits AD and aMCI remain research question. This study aimed examine responses relationship between function AD, aMCI, healthy controls (HC). included 30 patients with early-stage 34 32 HC. Patients showed...

10.1080/13825585.2023.2198191 article EN Aging Neuropsychology and Cognition 2023-04-02

To compare acute nystagmus characteristics of posterior circulation stroke (PCS) and vestibular neuritis (AVN) in the emergency room (ER) within 24 h presentation.ER-based video-nystagmography (VNG) was conducted, recording ictal 101 patients with PCS (on imaging) 104 AVN, diagnosed on accepted clinical test criteria.Patients brainstem (38/101, affecting midbrain (n = 7), pons 19), medulla 12)), cerebellum (31/101), both (15/101) or other locations (17/101) were recruited. Common territories...

10.1007/s00415-022-11202-y article EN cc-by Journal of Neurology 2022-07-18

Objectives: Vestibular migraine (VM) is an under-recognized entity with substantial burden for the individual and society. The underlying mechanism of VM its distinction from other mechanisms still remain unclear. Inflammatory pathways have been suggested to contribute vestibular migraine. Our aim was further investigate possible role inflammation in pathophysiology VM.Methods: We recruited 30 patients diagnosed according ICHD-3 criteria 50 gender- age-matched controls. Blood samples were...

10.1080/00207454.2019.1681994 article EN International Journal of Neuroscience 2019-10-18

Immune checkpoint inhibitors (ICIs), such as pembrolizumab, have revolutionized cancer treatment by enhancing the immune system's response to malignancies. However, these therapies are associated with immune-related adverse events (irAEs), including neuromuscular complications myasthenia gravis, myositis, and myocarditis. We describe two male patients, aged 67 68, small cell non-small lung cancers, who developed progressive symptoms, ptosis, diplopia, generalized weakness, after receiving...

10.1097/cad.0000000000001665 article EN Anti-Cancer Drugs 2024-10-16

Purpose To find out clinical features associated with poor response to treatment in vestibular migraine (VM)Methods VM patients treated drugs recommended prophylaxis were included this multicenter study. Migraine including type, age of onset headache and vertigo attacks, attack frequency, intensity, symptoms, triggering factors, presence interictal dizziness/imbalance, anxiety, depression, history motion sickness, family noted. Amitriptyline, flunarizine, propranolol, topiramate venlafaxine...

10.1080/01616412.2022.2056341 article EN Neurological Research 2022-03-29

Prosaccade task is a widely used objective method to evaluate reflexive saccade and visual attention. The study aimed investigate prosaccade stimulus eccentricity, compare parameters in patients with Alzheimer's disease dementia (AD), amnestic mild cognitive impairment (aMCI), neurotypical adults (NA), examine the relationship between neuropsychological tests.Thirty AD, 34 aMCI, 32 NA were included study. Eye movements recorded EyeLink 1000 Plus task, this evaluated function comprehensive...

10.1080/13803395.2023.2183937 article EN Journal of Clinical and Experimental Neuropsychology 2022-11-26

AbstractBackground Vestibular Migraine (VM) is a frequent cause of recurrent spontaneous vertigo. While some report normal Video Head Impulse Test (vHIT) in VM, others observed abnormal results on this test. Whether or not methodological discrepancies could be the these differences known. There are 2 vHIT methods: subjects fixating an earth-fixed target (HIMP paradigm) head-fixed target, suppression head impulse test (SHIMP paradigm).Objectives The present study aimed to compare VM patients...

10.1080/00016489.2023.2284877 article EN Acta Oto-Laryngologica 2023-10-03

To find out if motion sickness susceptibility (MSS) of vestibular migraine (VM) patients and only (MO) can be reliably detected with a single simple question: "Can you read while travelling in car without getting sick?".

10.1016/j.bjorl.2023.101382 article EN cc-by Brazilian Journal of Otorhinolaryngology 2023-12-19

A female 27 presented with nausea and diplopia for 1 week. On examination she had normal vertical gaze but would develop convergence miosis whenever made horizontal saccades. Pupils were 6 mm unreactive to light. MRI showed extensive hyperintensity in the dorsal midbrain thalamus. Spinal CSF both normal. Serum aquaporin-4-antibody was positive. She treated steroids plasmapheresis after 3 months spasm resolved pupils remained unreactive. Neuromyelitis optica often presents brainstem signs,...

10.1016/j.ensci.2017.03.001 article EN cc-by-nc-nd eNeurologicalSci 2017-03-06

Objective: Multiple sclerosis (MS) is a heterogeneous disease with clinical and immunological features.Most MS cases occur sporadically, but considerable proportion of patients have family history MS.The etiology pathophysiology remain unclear.Recent epidemiological gene expression studies indicated that dysregulation microRNAs (miRNAs) may play role in pathogenesis.This study aimed to evaluate the differential miRNAs sporadic (sMS) familial (FMS) patients. Materials Methods:This...

10.4274/meandros.galenos.2023.71135 article EN Meandros Medical And Dental Journal 2023-12-28

Abstract Moraxella catarrhalis is one of the major pathogens respiratory and middle ear infections. Attachment this bacterium to surface human pharyngeal epithelial cells first step in pathogenesis This study revealed that sulfatide might act as a binding molecule for attachment M. cells. Furthermore, six different synthetic sulfatides were found inhibit significantly at an optimum concentration 10 μg/ml. Synthetic may have potential be used therapy prevent

10.1111/j.1348-0421.2006.tb03873.x article EN Microbiology and Immunology 2006-12-01

A temporal overlap between vestibular symptoms, such as vertigo and head movement intolerance, migraine headache, photophobia, phonophobia, is a requisite diagnostic criterion for the diagnosis of (VM). Diagnostic criteria VM have been proposed by an International Vestibular Research Group (the Bárány Society) headache research group (International Headache Society); however, in practice, it still acceptable to divide patients suspected into “definite VM” “probable groups. Here,...

10.4103/nsn.nsn_72_20 article EN cc-by-nc-sa Neurological Sciences and Neurophysiology 2020-01-01

Objective: The aim of study was to evaluate the differential expressions miRNAs in both sporadic and familial MS patients. Background: Multiple sclerosis (MS) is a heterogeneous disease terms clinical immunological features. Although most cases occur sporadically, considerable proportion patients are related by family. MicroRNA (miRNA)s small non-coding RNA that mediate mRNA translation repression or degradation. regulate more than 100 genes they could also have focused insight into diseases...

10.1212/wnl.88.16_supplement.p3.383 article EN Neurology 2017-04-18
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