Ruchika Sangani

ORCID: 0000-0003-1982-4408
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About
Contact & Profiles
Research Areas
  • Pulmonary Hypertension Research and Treatments
  • Systemic Sclerosis and Related Diseases
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Medical Imaging and Pathology Studies
  • Cardiovascular Function and Risk Factors
  • Asthma and respiratory diseases
  • Research on Leishmaniasis Studies
  • Sarcoidosis and Beryllium Toxicity Research
  • Venous Thromboembolism Diagnosis and Management
  • Vascular Anomalies and Treatments
  • Bacillus and Francisella bacterial research
  • Health disparities and outcomes
  • Acute Myocardial Infarction Research
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Inflammatory Bowel Disease
  • Infectious Diseases and Tuberculosis
  • Eosinophilic Esophagitis
  • Sepsis Diagnosis and Treatment
  • Inhalation and Respiratory Drug Delivery
  • Macrophage Migration Inhibitory Factor
  • Tuberculosis Research and Epidemiology
  • Health Systems, Economic Evaluations, Quality of Life
  • IL-33, ST2, and ILC Pathways
  • Galectins and Cancer Biology
  • Respiratory and Cough-Related Research

University of California, Los Angeles
2025

Boston University
2019-2024

Boston Medical Center
2019-2024

University Medical Center
2019

SUNY Upstate Medical University
2016

: Rationale The comparative effectiveness of biologics used as add-on therapy in the management difficult-to-control asthma is unclear. Objective To compare dupilumab, mepolizumab and benralizumab among patients with asthma. Methods Retrospective multicenter cohort study adult started on or from a electronic health record claims-based database between October 19, 2018 September 30, 2022. Propensity score matching was to minimize bias non-randomized treatment assignment; prespecified alpha...

10.1513/annalsats.202306-566oc article EN Annals of the American Thoracic Society 2024-01-19

Systemic sclerosis-related pulmonary hypertension (SSc-PH) is a common complication of SSc associated with accelerated mortality. The present study was undertaken to investigate whether cardiac axis deviation indicates abnormalities in function allowing for prognostication disease severity and mortality.This retrospective which electrocardiograms (ECGs) were reviewed their association echocardiography cardiopulmonary hemodynamics on right-sided heart catheterization. primary outcome observed...

10.1002/acr.24724 article EN Arthritis Care & Research 2021-06-04

Patients with systemic sclerosis complicated by both pulmonary hypertension (SSc-PH) and interstitial lung disease (SSc-PH-ILD) have poor prognosis compared to those SSc-PH or SSc-ILD alone. Little is known of how ILD severity affects outcomes in SSc-PH, PH SSc-ILD. Herein, we aimed delineate clinical features patients determine what degree contribute mortality SSc. We conducted parallel retrospective studies cohorts categorized function testing cardiopulmonary hemodynamics. Our primary...

10.1002/pul2.12117 article EN cc-by-nc Pulmonary Circulation 2022-07-16

Lung function declines over the course of adulthood; however, a consensus on normal range decline in an individual's lung is lacking.

10.1016/j.chpulm.2024.100058 article EN cc-by-nc-nd CHEST Pulmonary 2024-04-15

Diagnosis of pulmonary hypertension (PH) in systemic sclerosis (SSc) requires an invasive right heart catheterization (RHC), often based on elevated estimated artery systolic pressure screening echocardiography. However, because the poor specificity echocardiography, a greater number patients undergo RHC than necessary, exposing to potentially avoidable complication risks. The development improved prediction models for PH SSc may inform decision-making these patients.

10.1002/acr.24969 article EN Arthritis Care & Research 2022-06-09

Tumor necrosis factor (TNF) blockers have revolutionized the treatment of rheumatoid arthritis (RA) and inflammatory bowel disease (IBD). Various side effects occur, mainly infections. However, some unexpected rare events recently emerged: they are qualified as paradoxical because occur after initiation TNF blocker which is normally used to treat them. These include new onset or exacerbation psoriasis, sarcoidosis, uveitis, IBD. We present a case patient who developed quiescent IBD during...

10.14309/00000434-201610001-02670 article EN The American Journal of Gastroenterology 2016-10-01
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