- Reproductive Physiology in Livestock
- Reproductive Biology and Fertility
- Genetic and phenotypic traits in livestock
- Sperm and Testicular Function
- Reproductive System and Pregnancy
- Animal health and immunology
- Effects of Environmental Stressors on Livestock
- Veterinary Equine Medical Research
- Ruminant Nutrition and Digestive Physiology
- Ovarian function and disorders
- Animal Genetics and Reproduction
- Milk Quality and Mastitis in Dairy Cows
- Reproductive biology and impacts on aquatic species
- Animal Behavior and Welfare Studies
- Molecular Biology Techniques and Applications
- Endometriosis Research and Treatment
- Veterinary Medicine and Surgery
- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Selenium in Biological Systems
- Reproductive Health and Technologies
- Growth Hormone and Insulin-like Growth Factors
- Hormonal and reproductive studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genetic Mapping and Diversity in Plants and Animals
University of Zurich
2016-2025
Center for Pediatric Endocrinology Zurich
2016-2025
University of Veterinary Medicine Hannover, Foundation
2008-2024
Agroscope
2024
Reproduktionsmedizin München
2018-2020
Dicle University
2015
Kafkas University
2015
Ondokuz Mayıs University
2015
Near East University
2015
Ludwig-Maximilians-Universität München
1998-2012
Reactive oxygen species (ROS)-induced oxidative stress is well known to play a major role in male infertility. Sperm are sensitive ROS damaging effects because as germ cells form mature sperm they progressively lose the ability repair DNA damage. However, how lesions affect early embryonic development remains elusive. Using cattle model, we show that fertilization using exposed caused developmental arrest at time of genome activation. The levels damage response did not directly correlate...
Advantages of pangenomes over linear reference assemblies for genome research have recently been established. However, potential effects sequence platform and assembly approach, or combining created by different approaches, on pangenome construction not investigated. Here we generate haplotype-resolved from the offspring three bovine trios representing increasing levels heterozygosity that each demonstrate a substantial improvement in contiguity, completeness, accuracy current Bos taurus...
Clinical and subclinical endometritis are known to affect the fertility of dairy cows by inducing uterine inflammation. We hypothesized that clinical or could disturbing molecular milieu environment. Here we aimed investigate endometrial signatures pathways affected endometritis. For this, Holstein Frisian at 42-60 days postpartum were classified as healthy (HE), (SE) (CE) based on veterinary examination animals histological evaluation corresponding biopsies. Endometrial transcriptome...
Transition period is a critical time for dairy cows because large proportion of clinical and subclinical diseases are observed in the first month after parturition. Occurrence negative energy balance associated with depressed immunity these conditions can affect oocyte quality further embryonic development. The aim this study was to assess effects balance-associated disorders on vitro embryo production (IVP) cattle. We hypothesized that metabolic and/or inflammatory have effect developmental...
The objective of this flow cytometric study was to examine plasma membrane integrity, mitochondrial potential (MMP) and the degree DNA fragmentation cryopreserved bovine sperm immediately (0 h) 3 h after thawing compare results with each other fertility bulls. Cryopreserved spermatozoa from 4 consecutive ejaculates 20 bulls were examined. Percentages intact (PMI) showing a high MMP (HMMP), respectively, determined by SYBR14/PI- JC-1 assays. analysed standard deviation index (SD-DFI)...
When pregnancy is established, interferon tau (IFNT), a well-known recognition signal in ruminants, secreted by embryonic trophoblast cells and acts within the uterus to prepare for pregnancy. IFNT as an endocrine factor on corpus luteum (CL) induce refractory ability against luteolytic action of PGF2 α. Hypothesising that may influence not only uterine environment but also CL cows via local or peripheral circulation, we investigated qualitative changes pregnant during maternal period (day...