- Autoimmune Bullous Skin Diseases
- Urticaria and Related Conditions
- Dermatologic Treatments and Research
- Celiac Disease Research and Management
- Systemic Lupus Erythematosus Research
- Dermatology and Skin Diseases
- Autoimmune and Inflammatory Disorders
- Psoriasis: Treatment and Pathogenesis
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Skin Protection and Aging
- Eosinophilic Esophagitis
- Eosinophilic Disorders and Syndromes
- Inflammatory Myopathies and Dermatomyositis
- Peripheral Neuropathies and Disorders
- Monoclonal and Polyclonal Antibodies Research
- Laser Applications in Dentistry and Medicine
- Skin Diseases and Diabetes
- Cutaneous Melanoma Detection and Management
- Vasculitis and related conditions
- Dermatological and COVID-19 studies
- Acne and Rosacea Treatments and Effects
- Drug-Induced Adverse Reactions
- Lymphoma Diagnosis and Treatment
- Body Contouring and Surgery
- Dermatological and Skeletal Disorders
University of Florence
2015-2025
Azienda Usl Toscana Centro
2021-2025
Abstract Background Tirbanibulin 1% ointment is approved for the field treatment of Olsen grade I actinic keratoses (AKs) face and scalp. Methods We performed a multicenter retrospective study involving 15 dermatologic units in Italy to investigate efficacy tolerability tirbanibulin real‐life setting. 250 patients were enrolled. Tirbanibulin, ointment, was applied daily five consecutive days. The measured with modifications Actinic Keratosis Area Severity Index (AKASI). A satisfactory...
The association between psoriasis and streptococcal infection has been widely explored in both children adults. However, the exact impact of Streptococcus pharyngeal on course is not fully comprehended. This study investigated effectiveness systemic antibiotic therapy conjunction with standard topical treatment for psoriatic patients concomitant throat infection. research involved 115 mild-to-moderate psoriasis, clinically assessed using Psoriasis Area Severity Index (PASI). Patients active...
The dermatological manifestations associated with intestinal diseases are becoming more frequent, especially now when new clinical entities, such as Non-Celiac Gluten Sensitivity (NCGS), identified. existence of this entity is still debated. However, many patients diagnosed NCGS that present have skin lesions need appropriate characterization.We involved 17 affected by non-specific cutaneous who got much better after a gluten free diet. For histopathological and immunopathological...
Abstract Pemphigus is a group of blistering disorders characterized by the formation intraepithelial blisters in skin and mucous membranes induced binding circulating autoantibodies to intercellular adhesion molecules. The pathogenesis complex not fully understood; however, genetic predisposition various triggers are widely accepted as key factors pemphigus development. A few cases new‐onset following coronavirus disease 2019 (COVID‐19) vaccination have already been published. present paper...
Patients with melanoma are especially encouraged to have regular follow- up visits their dermatologist and perform total-body skin examination on a routine basis identify new pigmented lesions or detect significant changes in existing naevi.To main risk factors (sex, age, number of common atypical naevi, family history, phototype) associated multiple primary melanomas (MPM) investigate the association between follow tumour thickness second melanoma.We performed retrospective analysis...
Hailey-Hailey disease (HHD) is a chronic, recurrent blistering disorder characterized clinically by erosions occurring primarily in intertriginous regions and histologically suprabasal acantholysis.We report long standing case of HHD initially unresponsive to cyclosporin, multiple topical systemic steroids. Good response was achieved with methotrexate 7,5 mg weekly for 16 week, intramuscularly, steroids as needed.In conclusion, we suggest that could be considered therapeutic option the...
Abstract Background Anti‐nuclear antibodies ( ANA ), anti‐extractable nuclear antigens ENA ) and anti‐ds DNA are often associated with cutaneous lupus erythematosus CLE variable frequency depending on skin subtype. However, specific data based large case‐series the pathogenetic, diagnostic prognostic meaning of such autoantibodies still lacking. Objective To characterize correlations between subtypes as well LE ‐non‐specific lesions their autoantibody pattern. Methods Epidemiological,...
Linear IgA bullous dermatosis (LABD) is a mucocutaneous autoimmune blistering disease affecting both adults and children. It caused by antibodies targeting multiple antigens along the basement membrane zone, leading to disruption of dermoepidermal junction development lesions which often presents in characteristic arrangement. Although most LABD cases have been reported be idiopathic, different triggers described, including several drugs infection. However, occurrence vaccine-induced not...
A few studies on vaccination in patients with rheumatic diseases, including arthritis, connective tissue vasculitis, and psoriatic arthropathy (PsA), demonstrated reduced production of neutralizing antibodies to SARS-CoV-2 Spike RBD (receptor-binding domain contained the N-terminal S1 globular head region) when compared general population.The aim our study was observe whether different therapies for PsA [methotrexate, anti-TNF antibodies, soluble TNF receptor (etanercept) or IL-17...
Abstract Background Blepharoplasty is one of the most popular esthetic procedures with an acceptable risk profile and a relatively quick procedure. Methods The aim was to evaluate efficacy safety new CO 2 1540‐nm laser‐assisted blepharoplasty technique applied upper lower eyelids. A total 38 patients were enrolled. Photographs taken before treatment at 6‐month follow‐up. One “blind” observer assessed performance this by ranking results in four categories eyelid esthetic: 1 = no or poor...
Psoriasis is a chronic immune-mediated inflammatory cutaneous disease characterized by elevated levels of cytokines and adipokine Lipocalin-2 (LCN-2). Recently, natural plant-based products have been studied as new antipsoriatic compounds. We investigate the ability leaf extract marine plant