Geoffrey R. Tompkins

ORCID: 0000-0003-1996-6107
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About
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Research Areas
  • Oral microbiology and periodontitis research
  • Dental materials and restorations
  • Endodontics and Root Canal Treatments
  • Probiotics and Fermented Foods
  • Dental Implant Techniques and Outcomes
  • Antimicrobial Resistance in Staphylococcus
  • Dental Research and COVID-19
  • Rabies epidemiology and control
  • Streptococcal Infections and Treatments
  • Forensic and Genetic Research
  • Bacterial Identification and Susceptibility Testing
  • Laser Applications in Dentistry and Medicine
  • Genomics and Phylogenetic Studies
  • Scientific and Engineering Research Topics
  • Oral Health Pathology and Treatment
  • Dental Radiography and Imaging
  • Nanoparticles: synthesis and applications
  • Oral health in cancer treatment
  • Dental Erosion and Treatment
  • Antimicrobial Peptides and Activities
  • Forensic Anthropology and Bioarchaeology Studies
  • Immune Response and Inflammation
  • Dental Anxiety and Anesthesia Techniques
  • Muscle and Compartmental Disorders
  • Bacterial biofilms and quorum sensing

University of Otago
2015-2025

Fisheries and Oceans Canada
2018

Bedford Institute of Oceanography
2018

Dalhousie University
2018

Walsh University
2011

Augusta University
1994-2001

University of Minnesota
1991

University of California, Davis
1972-1973

Histochemical evaluation of muscles from piglets, lambs and calves allows the conclusion that in these species, as was previously reported for chick muscle (Ashmore Doerr, 1971), there are two basic fiber types. These have been termed a β based on myosin ATPase activity. Initially, fibers "red", but capacity to transform an aerobic state metabolism (aR) anerobic (aW). remain "red" throughout their lifespan. Transformation is primarily concerned with changes energy-producing enzymes,...

10.2527/jas1972.34137x article EN Journal of Animal Science 1972-01-01

"DARK-CUTTING" meat commonly results when cattle are subjected to prolonged stress just prior slaughter. Subcutaneous injections of epinephrine administered for 24 48 hr. slaughter has been shown mimic the condition produced by natural conditions. Epinephrine acts accelerate glycogen metabolism in muscle tissue. Low stores at preclude development a desirable pH after death. When remains elevated carcass, mitochondrial respiration high and myoglobin is deoxygenated. A dark red color results....

10.2527/jas1973.36133x article EN Journal of Animal Science 1973-01-01

Parmar D, Hauman CHJ, Leichter JW, McNaughton A, Tompkins GR. Bacterial localization and viability assessment in human ex vivo dentinal tubules by fluorescence confocal laser scanning microscopy. International Endodontic Journal, 44, 644–651, 2011. Aim To develop a convenient method for the quantification of live dead bacteria mineralized tubules. Methodology The roots from single-rooted teeth (n = 12) were infected with Enterococcus faecalis V583 either treated calcium hydroxide paste or...

10.1111/j.1365-2591.2011.01867.x article EN International Endodontic Journal 2011-02-26

A novel silver nanoparticle (AgNP) formulation was developed as a targeted application for the disinfection of carious dentine. Silver nitrate (AgNO 3 ) chemically reduced using sodium borohydrate (NaBH 4 in presence dodecyl sulfate (SDS) to form micelle aggregate structures containing monodisperse 6.7- 9.2-nm stabilized AgNPs. AgNPs were characterized by measurement electrical conductivity and dynamic light scattering, scanning electron microscopy, transmission inductively coupled plasma...

10.1177/0022034517736495 article EN Advances in Dental Research 2018-01-22

MEPS Marine Ecology Progress Series Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsTheme Sections 597:115-135 (2018) - DOI: https://doi.org/10.3354/meps12589 Sponge assemblages and predicted archetypes in eastern Canadian Arctic Francisco Javier Murillo1,*, Ellen Kenchington1, Gabrielle Tompkins1,2, Lindsay Beazley1, Emily Baker1, Anders Knudby3, Wojciech Walkusz4 1Department of Fisheries Oceans, Bedford...

10.3354/meps12589 article EN Marine Ecology Progress Series 2018-04-10

To establish how oral bacteria are related to cough sensitivity and pneumonia in a clinical stroke population.Stroke patients at risk of colonisation by respiratory pathogens due, part, sudden discontinuation effective hygiene. When combined with reduced reflex sensitivity, aspiration contaminated oropharyngeal contents can lead pneumonia. Relationships between bacteria, have not been established.A total 102 acute underwent saliva sampling testing admission hospital, discharge one month. A...

10.1111/joor.12903 article EN Journal of Oral Rehabilitation 2019-11-08

The focus of this symposium was to present new information on the morphogenesis Candida albicans, particularly how it relates signal transduction pathways and other genes involved in regulation morphogenesis. In addition, we discuss role adherence colonization oral cavity by organism mannan as an adhesin that recognizes human red blood cell. C. albicans utilizes at least two regulate its conversion from a yeast form filamentous growth (hyphae). One these is similar Saccharomyces cerevisiae...

10.1080/mmy.38.s1.125.137 article EN Medical Mycology 2000-01-01

The production of streptocins STH(1) and STH(2) by Streptococcus gordonii DL1 (Challis) is directly controlled the competence regulon, which requires intact comR comAB loci. streptocin (sth) locus comprises two functional genes, sthA sthB. Whereas activity alone, depends on both genes.

10.1128/jb.01174-06 article EN Journal of Bacteriology 2007-02-03

Background . Intraoral adjustment and polishing of dental ceramics often affect their surface characteristics, promoting increased roughness consequent biofilm growth. This study correlated to development with four commercially available ceramic materials. Methods Four materials (Vita Enamic®, Lava™ Ultimate, Vitablocs Mark II, Wieland Reflex®) were prepared as per manufacturer instructions. Seventeen specimens each material adjusted polished simulate clinical intraoral procedures another...

10.1155/2017/7627945 article EN cc-by International Journal of Dentistry 2017-01-01

Biofilm accumulation can lead to enamel decalcification, gingivitis, and periodontal disease. The objective of this study was compare the biofilm under in vivo conditions consequent ex acid production demineralization around material used for "off-the-shelf" conventional CAD/CAM orthodontics bands. design required both vitro approaches. An experimental model utilized combine exposure an formed cariogenic achieve objective. Twenty-one consenting participants took part study. Participants wore...

10.1002/jbm.b.35573 article EN cc-by-nc-nd Journal of Biomedical Materials Research Part B Applied Biomaterials 2025-04-01

Several recent studies have investigated the association between interleukin-1 genotype and periodontitis in clinical samples, where generalizability is an issue. The aim of this study was to investigate adult IL-1 a population-based sample 26-year-olds. Based on probing depth (PD) measurements, participants were divided into three disease groups: "Severe" (1+ teeth with 5+mm PD; N = 25), "Moderate" (2+ 4+mm 36), "Controls" (the remainder ; 800). "periodontitis-associated genotype" (PAG;...

10.1177/00220345010800080401 article EN Journal of Dental Research 2001-08-01

Background . Topical application of manuka honey is effective in the treatment burns and soft-tissue infections. The aim this study was to assess antibacterial activity against plaque-associated bacteria vitro order evaluate potential as an adjunct periodontal treatment. Materials Methods minimum bacteriostatic bactericidal concentrations (MIC MBC) were compared those white clover a variety bacteria, at natural neutral pH. Dissolved calcium measured following incubation honeys with...

10.1155/2017/9874535 article EN cc-by International Journal of Dentistry 2017-01-01

A radioligand assay was designed to detect and compare specific hemin binding by the periodontal anaerobic black-pigmenting bacteria (BPB) Porphyromonas gingivalis Prevotella intermedia. The included physiological concentrations of hemin-binding protein rabbit serum albumin (RSA) prevent self-aggregation nonspecific interaction with cellular components. Under these conditions, heme-starved P. intermedia cells (two strains) expressed a single site species (4,100 4,600 sites/cell) dissociation...

10.1128/jb.179.3.620-626.1997 article EN Journal of Bacteriology 1997-02-01

To assess the amount of contamination remaining on used healing abutments after autoclaving and to compare effectiveness two additional decontamination methods.After autoclaving, a total 120 were divided equally into three groups: only (group 1); air-flow polishing (Master Piezon, EMS) using erythritol powder (AIR-FLOW PLUS, 2); sodium hypochlorite (NaOCl; 25 g/L) treatment 3). Residual contaminants stained Phloxine B (400 g/mL), photographed light microscope with digital capture system...

10.11607/ijp.5881 article EN The International Journal of Prosthodontics 2018-07-30

Bite mark injuries often feature in violent crimes. Conventional morphometric methods for the forensic analysis of bite marks involve elements subjective interpretation that threaten credibility this field. Human DNA recovered from has highest evidentiary value, however recovery can be compromised by salivary components. This study assessed feasibility matching bacterial sequences amplified experimental to those obtained teeth responsible, with aim evaluating capability three genomic regions...

10.1371/journal.pone.0051757 article EN cc-by PLoS ONE 2012-12-19

This study assessed, for forensic purposes, the feasibility of genotypically matching oral streptococci recovered from recent human bite marks with those teeth biter.Streptococci were isolated incisors eight volunteers. Arbitrarily primed PCR (AP-PCR) distinguished 106 streptococcal genotypes among participants, each harbouring at least distinct strains. In a crime simulation, sample an experimental mark was analysed by experimenter unaware its origin. The bacteria unambiguously matched to...

10.1111/j.1365-2672.2005.02703.x article EN Journal of Applied Microbiology 2005-08-24

Objectives The objective of this scoping review was to map evidence electrolysed oxidising water (EOW) as a biocide for dental applications relevance older people and identify research gaps. Background EOW is an emerging, “green,” cost‐effective biocide. There are no reviews on the landscape either antiseptic or disinfectant in healthcare its suitability oral people. Materials Methods follows PRISMA Extension Scoping Reviews (PRISMA‐ScR) guidelines. Database searches (Google Scholar, PubMed,...

10.1111/ger.12712 article EN cc-by-nc-nd Gerodontology 2023-09-11
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