A5022835740- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Cardiac pacing and defibrillation studies
- Cardiac and Coronary Surgery Techniques
- Coronary Interventions and Diagnostics
- Aortic aneurysm repair treatments
- Cardiac Structural Anomalies and Repair
- Cardiac Arrhythmias and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Congenital Heart Disease Studies
- Cardiac Ischemia and Reperfusion
- Respiratory Support and Mechanisms
- Cardiovascular Function and Risk Factors
- Mechanical Circulatory Support Devices
- Infectious Aortic and Vascular Conditions
- Cardiac Imaging and Diagnostics
- Scientific Computing and Data Management
- Cardiac Arrest and Resuscitation
- Coronary Artery Anomalies
- Hip and Femur Fractures
- Vitamin C and Antioxidants Research
- Distributed and Parallel Computing Systems
- Anesthesia and Pain Management
- Management of metastatic bone disease
University Hospitals of Cleveland
2020-2025
Case Western Reserve University
2020-2024
University School
2022-2024
University of Chile
2009-2024
Hospital San Borja Arriarán
2013-2024
Valve (United States)
2022
Western University of Health Sciences
2022
University Hospitals Cleveland Medical Center
2021
Clínica Las Condes
2013-2019
Universitat Politècnica de València
2016
Abstract: Ischaemia reperfusion injury is a pathophysiological event that occurs after cardiac surgery with extracorporeal circulation. This clinical has been associated the induction of oxidative and inflammatory damage in atrial tissue. Here, we tested whether combined omega 3 polyunsaturated fatty acids (n‐3 PUFA)‐antioxidant vitamin protocol therapy reduces tissue damage. trial assigned 95 either‐sex patients to supplementation n‐3 PUFA (2 g/day), or matching placebo groups, 7 days...
Patients with isolated functional or recurrent tricuspid regurgitation are often denied surgery because they considered to be at high risk. Transcatheter valve therapy provides a less invasive alternative for associated right heart failure. We have evaluated the feasibility of transcatheter implantation NaviGate valved stent in long-term swine model. The was successfully implanted through transjugular and transatrial approaches on beating excellent hemodynamic performance. No conduction...
Patients who undergo permanent pacemaker (PPM) implantation after transcatheter aortic valve replacement (TAVR) have a worse outcome. The aim of this study was to identify risk factors outcomes in patients with post-TAVR PPM implantation.This is single-centre, retrospective consecutive underwent from 11 March 2011 9 November 2019. Clinical were evaluated by landmark analysis cut-off at 1 year the implantation. Of 1389 TAVR during duration and total 110 included final analysis. Right...
Objective: To report the short-term real-word clinical and hemodynamic performance from MANTRA study in patients undergoing minimally invasive mitral valve repair (MI-MVr) with MEMO 4D ring (Corcym S.r.l., Saluggia, Italy). Methods: is an ongoing prospective study, evaluating real-life safety data on Corcym devices. Clinical echocardiographic core lab–assessed outcomes were collected preoperatively, at discharge, follow-up, Kansas City Cardiomyopathy Questionnaire 12 (KCCQ-12) questionnaires...
Background: Transcatheter aortic valve replacement is approved for treatment of patients with severe stenosis across the spectrum risk. While considering broader indications use, transcatheter in large native annuli has become increasingly important. Methods: Patients tricuspid undergoing using Evolut R or PRO+ 34 mm valves (Medtronic, Minneapolis, MN) Society Thoracic Surgeons/American College Cardiology Valve Therapy Registry between October 2016 and September 2020 were stratified...
Objective Aortic dissection and aortic aneurysm rupture are emergencies their clinical outcomes have improved over the past two decades; however, whether this has translated into lower mortality across countries remains an open question. The purpose of study was to compare trends from between UK, Japan, USA Canada. Methods We analysed WHO database determine in four 2000 2019. Age-standardised rates per 100 000 persons were calculated, annual percentage change estimated using joinpoint...
The aim of this study is to report the preliminary real-word clinical and hemodynamic performance from MANTRA in patients undergoing aortic valve replacement with Perceval PLUS sutureless valve.
Abstract Background Transcatheter aortic valve replacement (TAVR) has become an established method of stenosis treatment but suffers from the risk heart block and pacemaker requirement. Risk stratification for patients who may develop remains imperfect. Simultaneously, myocardial fibrosis as measured by cardiac magnetic resonance imaging (CMR) been demonstrated a prognostic indicator ventricular recovery mortality following TAVR. However, association CMR‐based measures with post‐TAVR...
The MANTA vascular closure device (VCD) represents a novel approach to achieving hemostasis after large-bore femoral access procedures. Numerous clinical studies have evaluated the efficacy of across range patient populations undergoing different However, there is still paucity data available concerning use devices in aiding decannulation venoarterial extracorporeal membrane oxygenation (VA-ECMO).
Aims:The aim of this study was to test the feasibility transcatheter mitral valve implantation NaviGate device in acute and chronic preclinical models. Methods results:We evaluated valved stent position an swine model (n=24, ≤5 days) through three different approaches -transatrial, transapical, transseptal -and a (n=12, >10 transatrial approach.The procedures were successful 83% studies (n=20) (n=10).Echocardiographic assessment showed low gradient across (mean <3 mmHg) left ventricular...
Memo 4D is a semi-rigid ring with an exclusive saddle shape and progressive increased anteroposterior diameter. This preliminary analysis reports 30-day clinical haemodynamic outcomes of the MANTRA sub-study.
Background Transcatheter aortic valve replacement with supra-annular transcatheter heart valves has been adopted in patients degenerated surgical valves. The next generation self-expanding Evolut PRO not evaluated failure. Methods and Results Patients undergoing procedures using the R or Society of Thoracic Surgeons American College Cardiology Valve Therapy Registry between April 2015 June 2019 were evaluated. performance was by clinical site echocardiography. In-hospital, 30-day, 1-year...
Recent trends in climate modeling find GRID computing a powerful way to achieve results by sharing geographically distributed and storage resources. In particular, ensemble prediction experiments are based on the generation of multiple model simulations explore, statistically, existing uncertainties weather forecast. this paper, we present application consisting state-of-the-art model. The main goal is provide tool that can be used researcher run ensemble-based predictions for sensitivity...
Transcatheter mitral valve implantation (TMVI) is a novel technology for patients with severe disease but at high surgical risk. Imaging guidance during the procedure critical successful device deployment. Identification of annular plane (MAP) fluoroscopy limited by lack clearly defined landmarks. We hypothesized that left circumflex-right coronary arteries (LCX-RCA) would have consistent relationship to MAP.We studied 25 gated cardiac computed tomography. identified MAP and LCX-RCA in mid...
Introduction: Endocarditis is a rare disease in children, especially those without previous heart disease, and Kingella Kingae (KK) rarely identified as the cause. Extracorporeal membrane oxyge nation (ECMO) support for both respiratory failure.