A5090770824- Dialysis and Renal Disease Management
- Parathyroid Disorders and Treatments
- Pharmacological Effects and Toxicity Studies
- Renal Transplantation Outcomes and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Vasculitis and related conditions
- Cardiac Arrest and Resuscitation
- Acute Myocardial Infarction Research
- Electrolyte and hormonal disorders
- Cardiac Arrhythmias and Treatments
- Renal Diseases and Glomerulopathies
- Cardiac Structural Anomalies and Repair
- Renal and Vascular Pathologies
- Reproductive Biology and Fertility
- Acute Kidney Injury Research
- Ovarian function and disorders
- Hormonal Regulation and Hypertension
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Chronic Kidney Disease and Diabetes
- Heart Failure Treatment and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Antibiotics Pharmacokinetics and Efficacy
Lake Erie College of Osteopathic Medicine
2025
Chungbuk National University Hospital
2012-2024
Chungbuk National University
2012-2023
University of North Carolina at Chapel Hill
2019-2020
University of Kentucky
2012-2019
Lexington VA Health Care System
2018
Konyang University
2017
Konyang University Hospital
2017
Seoul National University Hospital
2006-2017
Johns Hopkins University
1995-2017
Patients with end-stage renal disease (ESRD) are at a high risk for hip fracture. Little is known about the for, and consequences of, fracture among patients non-dialysis-requiring chronic kidney (CKD). We examined incidence of fracture, in-hospital mortality, length stay, costs ESRD, CKD, normal or near function. Using Healthcare Cost Utilization Project's Nationwide Inpatient Sample, nationally representative database, we identified hospitalizations in 2010. incorporated data from United...
Secondary hyperparathyroidism is common among patients with ESRD. Although medical therapy for secondary has changed dramatically over the last decade, rates of parathyroidectomy across United States population are unknown. We examined temporal trends in parathyroidectomy, in-hospital mortality, length hospital stay, and costs hospitalization.Using Healthcare Cost Utilization Project's Nationwide Inpatient Sample, a representative national database on stay regardless age payer States, we...
Summary Background Non‐alcoholic fatty liver disease ( NAFLD ) is known to be associated with polycystic ovary syndrome PCOS ). However, most studies investigated the prevalence of in obese patients. Aim To compare non‐obese women or without , and assess an independent association between a Asian cohort. Methods This was case–control study using prospective After subjects other potential causes chronic were excluded, 275 892 controls enrolled. determined by hepatic ultrasonography. Main...
We evaluated the impact of serum uric acid (SUA) on mortality in patients with chronic dialysis. A total 4132 adult dialysis were enrolled prospectively between August 2008 and September 2014. Among them, we included 1738 who maintained for at least 3 months had available SUA database. categorized time averaged-SUA (TA-SUA) into 5 groups: <5.5, 5.5-6.4, 6.5-7.4, 7.5-8.4, ≥8.5 mg/dL. Cox regression analysis was used to calculate hazard ratio (HR) all-cause according group. The mean TA-SUA...
The objectives of this study were to define the distribution modified Ferriman-Gallwey (mF-G) score in a random group Korean women and any association(s) between hirsutism endocrine/metabolic markers.A single investigator assessed mF-G prospectively 1010 women, who consulted health-care center as part check-up for employment. Logistic regression models utilized test relationships presence levels markers.Subjects had scores ranging from 0 19, 505 subjects (50.0%) an zero. Of subjects, 95.1%...
Endothelial cell damage and impaired angiogenesis substantially contribute to the progression of chronic renal failure (CRF). The effect endothelial progenitor (EPC) treatment on CRF is yet be determined. We performed 5/6 nephrectomy induce in C57BL/6 mice. EPCs were isolated from bone marrow, grown conditioned medium, characterized with surface marker analysis. serial changes kidney function histological features scrutinized mice EPC-treated (EPC-CRF) Adoptively transferred present at...
AIMTo determine the prevalence of QT prolongation in a large series end stage liver disease (ESLD) patients and its association to clinical variables mortality. METHODSThe interval was measured corrected for heart rate each patient, with prolonged cutoff defined as > 450 ms males 470 females.
Anti-Müllerian hormone (AMH) has been suggested as a marker of ovarian reserve and predictor response to controlled hyperstimulation (COH). Several studies have demonstrated AMH changes during follicular luteal phases COH, but not after human chorionic gonadotrophin (hCG) administration. The objectives this study were investigate in levels the entire COH cycle clarify regulatory mechanism secretion. In addition, we analyzed outcome parameters determine optimal timing for measurement predict...
In osteoarthritis (OA), chondrocytes in cartilage undergo phenotypic changes and senescence, restricting regeneration favoring disease progression. Although senescence biomarker p16INK4a expression is known to induce aging by halting the cell cycle, therapeutic applications for targeting are limited. Here, we aimed reduce damage alleviate pain using nanoparticles OA. The of human OA synoviocytes from patients with knee was measured levels p16INK4a, tumor necrosis factor (TNF)-α, interleukin...
Ultraviolet (UV) irradiation affects the function and complexion of skin by inducing changes in physical properties through formation erythema, proliferation epithelial cells, DNA damage, activation or inactivation various enzymes proteins, free radical formation. In this study, authors intended to observe overall course barrier reflectance induced photodamage, healing reaction time, alteration complexion.The subjects were chosen from 15 healthy Korean men 20-35 age, that fall into category...
Ceftriaxone is widely used in patients for the treatment of serious gram-negative infections.Ceftriaxone can induce some potential side effects, including neurotoxicity, however, nonconvulsive status epilepticus has rarely been reported.We report a case acute reversible neurotoxicity associated with ceftriaxone.A 65-yr-old woman chronic kidney disease developed altered consciousness during ceftriaxone urinary tract infection.The electroencephalogram demonstrated continuous bursts...
Parathyroidectomy is the only curative therapy for patients with primary hyperparathyroidism. However, incidence, correlates and consequences of parathyroidectomy hyperparathyroidism across entire US population are unknown. We evaluated temporal trends in rates inpatient hyperparathyroidism, associated in-hospital mortality, length stay, costs. used Healthcare Cost Utilization Project Nationwide Inpatient Sample (NIS) from 2002-2011. Parathyroidectomies were identified using International...
Background The exponential increase in the incidence of Methicillin-resistant Staphylococcus aureus (MRSA) infections has imposed great burdens on hospital systems. Although there are vast antibiotic options for treatment MRSA, eradication is often tough. There not many studies highlighting post-discharge readmission rates MRSA patients. Objective primary aim study was to describe 30-day rate patients hospitalized with a positive culture from single center, secondary analyzing 90-day rates....
Increased risk of lung cancer has been associated with employment in the steel industry. This association is thought to be due part increased concentrations polycyclic aromatic hydrocarbons (PAHs) air found this work environment. Measurement PAH metabolites human urine provides a means assessing individual internal dose PAHs. study examined relative contribution occupation and smoking urinary concentration 1-hydroxypyrene glucuronide (1-OHPG) among group workers at plant.Concentrations...
Nephrotic syndrome is an unusual manifestation of IgA Nephropathy (IgAN). Some cases respond to steroid treatment. Here we describe a case-series IgAN patients with steroid-responsive nephrotic syndrome. Twelve were evaluated and followed up. All presented generalized edema. Renal insufficiency was found in two patients. The renal biopsy eight revealed wide foot process effacement addition the typical features IgAN. They showed complete remission after therapy. Seven relapses reported five...
Renin-angiotensin-system (RAS) blockade is thought to slow renal progression in patients with chronic kidney disease (CKD). However, it remains uncertain if the habitual use of RAS inhibitors affects and outcomes pre-dialysis advanced CKD. In this multicenter retrospective cohort study, we identified 2,076 CKD (stage 4 or 5) from a total 33,722 patients. users were paired non-users for analyses using inverse probability treatment-weighted (IPTW) propensity score (PS) matching. The death,...