- Musculoskeletal synovial abnormalities and treatments
- Orthopedic Surgery and Rehabilitation
- Hip disorders and treatments
- Advanced MRI Techniques and Applications
- Medical Imaging Techniques and Applications
- Shoulder Injury and Treatment
- Spine and Intervertebral Disc Pathology
- Radiation Dose and Imaging
- Advanced Radiotherapy Techniques
- Pancreatic function and diabetes
- Spinal Fractures and Fixation Techniques
- Tendon Structure and Treatment
- Orthopaedic implants and arthroplasty
- Advanced X-ray and CT Imaging
- Elbow and Forearm Trauma Treatment
- Cervical and Thoracic Myelopathy
- Peripheral Nerve Disorders
- Xenotransplantation and immune response
- Knee injuries and reconstruction techniques
- Bone health and osteoporosis research
- Diabetes and associated disorders
- Gastrointestinal disorders and treatments
- Hip and Femur Fractures
- Diabetes Management and Research
- Nutrition and Health in Aging
Chung-Ang University
2019-2025
Chung-Ang University Hospital
2016-2025
Pusan National University Yangsan Hospital
2024
Chonnam National University
2020
University of Ulsan
2018
Asan Medical Center
2018
Ulsan College
2018
Changwon National University
2016
Gyeongsang National University
2016
Seoul National University Bundang Hospital
2015
Glucose-dependent insulinotropic polypeptide (GIP) potentiates glucose-stimulated insulin secretion, biosynthesis, and beta-cell proliferation survival. In previous studies GIP was shown to promote survival by modulating the activity of multiple signaling modules regulating gene transcription pro- anti-apoptotic bcl-2 family proteins. We have now evaluated mechanisms which regulates dynamic interactions between cytoplasmic members mitochondria in INS-1 cells during apoptosis induced...
Objective:The purpose of this study was to evaluate the reliability a new magnetic resonance imaging (MRI) grading system for cervical neural foraminal stenosis (NFS).Materials and Methods: Cervical NFS at bilateral C4/5, C5/6, C6/7 classified into following three grades based on T2-weighted axial images: Grade 0 = absence NFS, with narrowest width foramen greater than extraforaminal nerve root (EFNR); 1 same or less (but more 50% of) EFNR; 2 EFNR.The MRIs 96 patients who were over 60 years...
Recently, laparoscopic resection for relatively small sized gastric gastrointestinal stromal tumors (GISTs) has been widely accepted as minimally invasive surgery. However, no report on the long-term safety and efficacy of this surgery large GISTs published to date.Between July 1998 January 2011, 104 consecutive patients who underwent were enrolled in retrospective study. We assessed clinicopathological characteristics, postoperative outcomes, patient survival, tumor recurrence.Of with...
The <i>Journal of Biomedical Optics</i> (JBO) is a Gold Open Access journal that publishes peer-reviewed papers on the use novel optical systems and techniques for improved health care biomedical research.
Purpose To evaluate the therapeutic effect of human embryonic stem cell (hESC)-derived multipotent mesenchymal cells (M-MSCs) on ketamine-induced cystitis (KC) in rats. Methods induce KC, 10-week-old female rats were injected with 25-mg/kg ketamine hydrochloride twice weekly for 12 weeks. In sham group, phosphate buffered saline (PBS) was instead ketamine. One week after final injection ketamine, indicated doses (0.25, 0.5, and 1×106 cells) M-MSCs (KC+M-MSC group) or PBS vehicle (KC directly...
Acute and chronic rotator cuff (RC) tears are common etiologies of shoulder disabilities. Despite the advanced surgical techniques graft materials available for tendon repair, high re-tear rate remains a critical challenge in RC healing. Inspired by highly organized nanotopography extracellular matrix (ECM) tissue shoulder, nanotopographic scaffolds developed using polycaprolactone repair regeneration tendons. The show appropriate flexibility mechanical properties application regeneration....
We analysed the association between extensor carpi ulnaris pathology and triangular fibrocartilage complex foveal tears. In total, 178 patients (58 120 controls) were retrospectively recruited. The patient group comprised individuals with Extensor was defined as presence of tenosynovitis, tendinosis high-grade tendon subluxation in magnetic resonance images. Tenosynovitis a high grade more prevalent than controls (43 vs. 23% 26 14%, respectively) whereas incidence did not significantly...
In recent years, wide beam computed tomography (CT) technique has become standard in radiation oncology whereas there is little information about dose assessments for the technique. A point measurement method was employed to assess doses of cone beams CT (CBCT) and multi detectors (MDCT). The both modalities were measured using thermoluminescence dosemeters (TLDs) head body phantoms. Four TLD chips placed at centre each peripheral channel measure doses. From measurements, weighted index CBCT...
We developed a new magnetic resonance indicator for necrotizing fasciitis (MRINEC) algorithm differentiating (NF) from severe cellulitis (SC). All adults with suspected NF between 2010 and 2018 in tertiary hospital South Korea were enrolled. Sixty-one patients diagnosed 28 SC. Among them, 34 15 SC underwent imaging (MRI). The MRINEC algorithm, two-step decision tree including T2 hyperintensity of intermuscular deep fascia diffuse peripheral fascia, 94% sensitivity (95% confidence interval...
We investigated sensitivity, specificity, and accuracy of magnetic resonance imaging (MRI) computed tomography arthrography (CTA), on the basis arthroscopic findings, to diagnose acetabular labral tears chondral lesions.We retrospectively reviewed results MRI subsequent CTA in 36 hips that underwent surgery (33 patients; 17 males [17 hips] 16 females [19 hips]; average age, 35 years). All patients had positive impingement test groin pain. analyzed by comparing with findings. Interobserver...
Journal Article Radiation dose from 3D rotational X-ray imaging: organ and effective with conversion factors Get access Sangroh Kim, Kim 1Medical Physics Graduate Program, Duke University, Durham 27705, NC, USA2Duke Dosimetry Laboratory, University Medical Center, 27710, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar David Sopko, Sopko 3Department of Radiology, Greta Toncheva, Toncheva 2Duke USA3Department Enterline, Enterline Bruno Keijzers, Keijzers...
In this study, we propose a generative data augmentation technique to overcome the challenges of severely limited when designing deep learning-based automated strabismus diagnosis system. We implement model based on StyleGAN2-ADA for system design and assess classification performance using two classifiers. evaluate capability our proposed method against traditional techniques confirm substantial enhancement in performance. Furthermore, conduct experiments explore relationship between...
Amid the deepening imbalance in supply and demand of allogeneic organs, xenotransplantation can be a practical alternative because it makes an unlimited organs possible. However, to perform on patients, source animals used must free from infectious agents. This requires breeding using assisted reproductive techniques, such as somatic cell nuclear transfer, embryo cesarean section, without colostrum derived designated pathogen-free (DPF) facilities. Most agents removed produced via these...
The purpose of this study was to establish a dose estimation tool with Monte Carlo (MC) simulations. A 5-y-old paediatric anthropomorphic phantom computed tomography (CT) scanned create voxelised and used as an input for the abdominal cone-beam CT in BEAMnrc/EGSnrc MC system. An X-ray tube model Varian On-Board Imager((R)) built To validate model, absorbed doses at each organ location standard-dose low-dose modes were measured physical MOSFET detectors; effective also calculated. In results,...
Although bismuth shields are frequently used in radiology to reduce radiation dose, its mechanism has not been fully investigated. Dosimetric characteristics of computed tomography (CT) were assessed with ion chamber and Monte Carlo (MC) simulations. Primary attenuation backscatter effects paediatric (2-ply) adult (4-ply) measured. Simulated CT beams for measurements. Radiation doses measured free-in-air the tissue-equivalent slabs. MC simulations same settings also performed. Mean dose...
The incretins, GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) are gastrointestinal hormones conferring a number of beneficial effects on β-cell secretion, survival proliferation. In previous study, it was demonstrated that delayed rectifier channel protein Kv2.1 contributes to apoptosis the prosurvival incretins involve PTMs (post-translational modifications), including phosphorylation acetylation. Since Kv1.5 overexpression also shown stimulate death,...
<b>Purpose:</b> To assess the clinical value of second-look ultrasound (US) examination for evaluation additional enhancing lesions detected on magnetic resonance (MR) imaging. <b>Materials and Methods:</b> Between May 2008 February 2011, 794 consecutive patients with histologically confirmed breast cancer underwent MR We included 101 132 imaging who US. The features lesion category according to Breast Imaging Reporting Data System (BI-RADS) were assessed US imaging, respectively....
To evaluate spine magnetic resonance imaging (MRI) inter-reader and intra-reader reliabilities using the thoracolumbar injury classification system severity score (TLICS) to analyze effects of reader experience on reliability possible reasons for discordant interpretations. Six radiologists (two senior, two junior radiologists, residents) independently scored 100 MRI examinations injuries assess morphology posterior ligamentous complex (PLC) integrity according TLICS. Inter-reader agreements...