Purpose: To evaluate the efficacy and safety of oral mineralocorticoid-receptor antagonist (MRa) therapy in three clinical presentations nonresolving central serous chorioretinopathy (CSCR) with chronic epitheliopathy. Methods: Retrospective case series consecutive patients CSCR treated eplerenone or spironolactone. Treatment criteria were: persistent subretinal fluid (SRF) lasting longer than 4 months; recurrent SRF 2 (SRF ≥ months) fundus autofluorescence gravitational tracks. Outcomes at...

A large series of silanes are proposed as new co-initiators for radical photopolymerization. Silanes in the presence benzophenone, isopropylthioxanthone, camphorquinone, or dyes (Eosin) found highly reactive and, many cases, even better than a reference amine co-initiator (ethyl dimethylaminobenzoate (EDB)). The ability to initiate polymerization process under air is excellent (better with amines), and inhibiting effect reduced eliminated. An enhancement rates Rp sometimes noted. For...

Chemically and topographically patterned surfaces have high potential as model for studying cell bacteria responses to surface chemistry topography at a nanoscale level. In this work, we demonstrated the possibility combine pulsed plasma polymerization UV-irradiation obtain topographical patterns chemical perfectly controlled microlateral resolution sub-micrometer depth Biological experiments were conducted using human osteoprogenitor cells Escherichia coli K12. Proliferation orientation of...

To suggest a clinical distinction between idiopathic polypoidal choroidal vasculopathy (PCV) and secondary polyps associated with neovascular age-related macular degeneration (NV-AMD).The study was retrospective case series of 52 eyes consecutive patients (31 females 21 males) diagnosed PCV. Initial diagnosis based on scanning laser ophthalmoscope-indocyanine green angiography (SLO-ICGA) in association fluorescein (FA) optical coherence tomography (OCT). All the data images were analyzed...

In Brief Purpose: To investigate the visual acuity results of eyes with neovascular age-related macular degeneration and refractory fluid despite monthly treatment ranibizumab, to differences between subretinal intraretinal cystic changes. Methods: Retrospective chart review consecutive treatment-refractory degeneration, defined as persistent or ranibizumab injections during 12 months more. Data were evaluated for baseline characteristics, type location fluid, mean change, number injections,...

Abstract In this article, germanes are presented as new coinitiators for both radical and cationic photopolymerization processes. For the free polymerization process, newly proposed structures characterized by efficiencies similar or better than reference amine. Germyl radicals also found to be excellent initiators promoted (FRPCP) of an epoxy resin. The associated reactivity is even under air. © 2008 Wiley Periodicals, Inc. J Polym Sci Part A: Chem 46: 3042–3047,

PURPOSE: To evaluate the safety and clinical outcome of phakic Visian toric implantable collamer lens (ICL) (STAAR Surgical, Monrovia, CA) insertion after corneal collagen cross-linking (CXL) in progressive keratoconus. METHODS: A retrospective study examined results two-step CXL ICL implantation 16 eyes 10 patients with The two procedures were done at an interval 6 months. Data collected preoperatively, 6-month follow-up visit CXL, implantation. RESULTS: induced a statistically significant...

The temperature-dependence of the volume and surface hydrophilicity a series water-swollen dense polymer brushes is measured by contact angle measurements in captive bubble configuration, ellipsometry, quartz crystal microbalance with dissipation monitoring (QCM-D). Thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) poly(di(methoxyethoxy)ethyl methacrylate) (PMEO2MA), strongly hydrophilic poly(N,N-dimethylacrylamide) (PDMA) poly(oligo(ethylene glycol) (POEGMA), weakly poly(2-hydroxyethyl...

Preparation of transparent and superhydrophobic coatings by co-deposition an aqueous solution amphiphilic fluorinated block copolymer with silica was developed.

Driven by an interest in developing a deeper understanding of stakeholder interests, this study undertakes dimensional analysis how different stakeholders assess project outcomes. Most importantly, our analysis, we take into consideration the largely unaccounted-for conceptual difference between success and failure. Data were collected over 2-year period (between 2013 2015) from 1631 nine countries. We analyzed survey data using three-way Multidimensional Scaling. found that most tend to be...

Background: The aim of this study was to evaluate the effects hemodialysis (HD) on visual acuity, intraocular pressure (IOP), and central foveal thickness (CFT) in patients with chronic kidney disease. Materials methods: Forty-nine eyes from 49 kidney-disease were analyzed. Causes disease included diabetes mellitus (n=9 patients), hypertensive nephrosclerosis (n=15 other causes (n=25 patients). All underwent HD Dialysis Unit Hôtel-Dieu de France Hospital. Best-corrected CFT, IOP evaluated...

Purpose . To evaluate the long-term safety and clinical outcome of phakic Visian toric implantable collamer lens (ICL) insertion after corneal collagen cross-linking (CXL) in progressive keratoconus. Methods This was a retrospective study 30 eyes (19 patients), with keratoconus, who underwent sequential CXL followed by ICL implantation 6 months. Results At baseline, had stage I, 14 II, 10 III keratoconus graded Amsler-Krumeich classification. months CXL, only K (steep) (max) decreased...

To evaluate the outer retinal layer (ellipsoid zone [EZ] and external limiting membrane [ELM]) changes following intravitreal aflibercept injections in eyes with treatment-naïve exudative age-related macular degeneration (eAMD) to correlate these fluid response visual improvement.A retrospective case series of 50 eAMD followed-up for 18 months. All patients underwent regular comprehensive ophthalmic examinations. The presence EZ disruption, ELM swelling, subretinal hyper-reflective exudation...

The purpose of this study was to assess the feasibility deep learning (DL) methods enhance prediction visual acuity (VA) improvement after macular hole (MH) surgery from a combined model using DL on high-definition optical coherence tomography (HD-OCT) B-scans and clinical features.We trained convolutional neural network (CNN) pre-operative HD-OCT macula with logistic regression features predict VA increase ≥15 Early Treatment Diabetic Retinopathy Study (ETDRS) letters at 6 months...

Purpose: To investigate the molecular composition of subretinal fluid (SRF) in central serous chorioretinopathy (CSCR) and rhegmatogenous retinal detachment (RRD) using proteomics metabolomics. Methods: SRF was obtained from one patient with severe nonresolving bullous CSCR requiring surgical fibrin removal, two patients long-standing RRD. Proteins were trypsin-digested, labeled Tandem-Mass-Tag fractionated according to their isoelectric point for identification quantification by tandem mass...

To analyze outcomes in recurrent rhegmatogenous retinal detachment (re-RRD) repair using pars plana vitrectomy (PPV) combined with scleral buckle (SB) at the first or second surgery. Patients primary uncomplicated RRD initial presentation who were operated for re-RRD between 2014 and 2018 included this retrospective cohort study (n = 127). compared based on surgery sequence: PPV then PPVSB (PPV-PPVSB: n 51, 40%), (PPVSB-PPV: 76, 60%). Anatomical functional evaluated success (2SS) defined as...