A5102002242- Circular RNAs in diseases
- Bariatric Surgery and Outcomes
- MicroRNA in disease regulation
- Smoking Behavior and Cessation
- Pancreatic function and diabetes
- Obesity and Health Practices
- School Health and Nursing Education
- Diabetes and associated disorders
- Endoplasmic Reticulum Stress and Disease
- Phytochemicals and Antioxidant Activities
- Cell death mechanisms and regulation
- Bioactive natural compounds
- Cardiovascular Disease and Adiposity
- Diet and metabolism studies
- Fatigue and fracture mechanics
- Cancer, Lipids, and Metabolism
- COVID-19 and Mental Health
- Patient Safety and Medication Errors
- Air Quality and Health Impacts
- Drug Transport and Resistance Mechanisms
- Genetics and Neurodevelopmental Disorders
- S100 Proteins and Annexins
- Curcumin's Biomedical Applications
- Diabetes Management and Research
- Hepatitis C virus research
Chongqing Medical University
2007-2025
Leipzig University
2025
Children's Hospital of Chongqing Medical University
2025
Second Hospital of Anhui Medical University
2018-2020
Anhui Medical University
2018-2020
Heilongjiang Bayi Agricultural University
2020
Northwest University
2019
China XD Group (China)
2019
Nanjing Medical University
2019
Mianyang Third People's Hospital
2007-2013
OBJECTIVE:To determine whether curcumin reverses the multidrug resistance of human colon cancer cells in vitro and vivo.METHODS: In a vincristine-resistant cell line cancer, viability curcumin-treated was determined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay.Rhodamine123 efflux evaluated to detect P-glycoprotein transporter activity, expression protein 1 survivin genes analyzed by reverse transcription polymerase chain reaction western blotting.In addition,...
Background: Medication safety is crucial in clinical care. Although many hospitals have implemented prospective prescription review systems to manage medication use, the impact of these on pediatric patients not yet fully understood. Objectives: We explore characteristics and economic impacts identify factors influencing intervention success rates. Design: This study adopted a cross-sectional design. Methods: Prospective tasks were compared outpatient our hospital between 2021 2023 assess...
Background This study aimed to investigate the associations between serum lipoprotein subclasses and long-term risk of gastrointestinal (GI) cancers enhance our understanding etiology GI cancers. Methods prospective cohort included 249,450 participants from UK Biobank. Cox proportional hazard models were used assess association 17 with Restricted cubic spline (RCS) analysis was employed corresponding dose–response relationships. Additionally, Mendelian randomization (MR) evaluate causal...
Mounting evidences reveal that circular RNAs (circRNAs) are critical to regulate biological behavior and process of tumor. Our objective is explore the role circRNA-PTN (circPTN) explain exact mechanism in hepatocellular carcinoma (HCC).Real-time polymerase chain reaction assay was used detect level circPTN miR-326. The proliferation cell measured by CCK-8 EdU assay. Western blot performed assess ErbB/PI3K expression. Luciferase RNA pull-down assays were carried out confirm interaction...
Since cellular uptake of PEG [poly(ethylene glycol)]-liposomal L-OHP (oxaliplatin) induces bioactive changes in CRC (colorectal cancer), we have investigated its apoptotic effect and anticancer mechanism. Human SW480 cells were treated with PEG-liposomal a caspase-8 inhibitor [Z-IETD-FMK (benzyloxycarbonyl-Ile-Glu-Thr-dl-Asp-fluoromethylketone)]. Apoptosis was measured by FCM (flow cytometry) TUNEL (terminal deoxynucleotidyl transferase-mediated dUTP nick-end labelling) assay. Expression...
Bariatric surgery has been used to reduce weight and shown be beneficial for hypertension control. However, little is known about the changes in blood pressure early stage after laparoscopic sleeve gastrectomy (LSG). We conducted a prospective study of 60 LSG patients with one year-follow-up. The was measured preoperatively from day 1 12 months postoperatively. use antihypertensives, body weight, ghrelin leptin levels were also recorded. Following LSG, excess loss (EWL) 72.6 ± 22.3% 83.1...
Polyphenols from mulberry roots possess antitumor activity and α-glucosidase, acetylcholinesterase tyrosinase inhibitory activities.
Hepatitis C virus (HCV) infection may lead to hepatic insulin resistance (IR), and endoplasmic reticulum (ER) stress has been found induce IR. In our previous study, naringenin (NGEN) had an sensitization effect on the HCV core protein (HCVCP) infected mouse livers. present we examined effects of NGEN HCVCP infection-induced ER investigated mechanism involved. We that XBP1s was up-regulated in livers HCV-infected patients, hepatocytes with infection, HCVCP-infected mice. induces liver by...
Background In China, people’s perceptions towards electronic cigarettes during Corona Virus Disease 2019 (COVID-19) pandemic compared with pre-pandemic conditions have not been explored. Exploring the of medical workers regarding e-cigarettes is crucial, as they serve a trusted source information and providers smoking cessation counselling for smokers. This cross-sectional study was designed to explore awareness among Chinese other groups in context COVID-19 pandemic. Methods A survey...
Medical students play an indispensable role in providing smoking cessation counseling. Despite the rapid increase tobacco use, there is little data on what Chinese medical know or are taught about it. This study aims to investigate relationship between students' education level, clinical experience, and counseling (TCC) provided by students.
Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in donor islets of different purity rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets isolated using digestion by ductal injection collagenase. Group Ⅰ (n=10): Separating cell preparations not purified, Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ and 11% Ficoll-400. The levels protein Nestin detected immunohistochemistry mRNA amplified RT-PCR. Results:...
Objective: To study the effects of α-enolase (ENO1) gene interference expression on proliferation, and cell cycle follicular granulosa cells from Zi geese. Methods: F1 were primary cultured (mixed culture), which divided into four groups: ENO1 group (RNAi), unrelated sequence (NC), culture (Control), transfection reagent (Lip). The apoptosis rate phase control detected by flow cytometry. Results:ENO1 slowed proliferation cells, increased apoptosis, proportion in G2/M phase. Conclusion:ENO1...
Background: Laparoscopic sleeve gastrectomy(LSG) has been widely used for treating severe obesity, but the recovery of epilepsy after surgery still remained unclear. Case presentation: We herein described a case 31-year-old female obese patient with who received laparoscopic gastrectomy in The Second Hospital Anhui Medical University 2018. After follow-up one year, her body mass index was dropped from 63.9 kg/m2 to 38.6 kg/m2. Besides she had complete seizure remission and freedom...